Search Results - "NATHAN, STEVEN"
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Progress in the Treatment of Pulmonary Hypertension Associated with Interstitial Lung Disease
Published in American journal of respiratory and critical care medicine (01-08-2023)“…Pulmonary hypertension, frequently complicating the course of patients with fibrotic interstitial lung disease, is associated with significantly increased…”
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Reply to Jin et al .: Inhaled Treprostinil after Initial Clinical Worsening: To Continue or Not to Continue, That's the Question
Published in American journal of respiratory and critical care medicine (15-05-2022)“…Nathan responds to comments from Jin et al regarding his study on whether to continue or not the use of inhaled treprostinil for pulmonary veno-occlusive…”
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Idiopathic pulmonary fibrosis: effects and optimal management of comorbidities
Published in The lancet respiratory medicine (01-01-2017)“…Summary Despite the development of pharmacological therapies that are effective in slowing the progression of idiopathic pulmonary fibrosis (IPF), it remains a…”
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Pulmonary hypertension in chronic lung disease and hypoxia
Published in The European respiratory journal (01-01-2019)“…Pulmonary hypertension (PH) frequently complicates the course of patients with various forms of chronic lung disease (CLD). CLD-associated PH (CLD-PH) is…”
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Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease
Published in The New England journal of medicine (28-01-2021)“…Patients with pulmonary hypertension due to interstitial lung disease were randomly assigned to inhaled treprostinil or placebo. At 16 weeks, there was a…”
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POINT: Should Every Patient With Idiopathic Pulmonary Fibrosis Be Referred for Transplant Evaluation? Yes
Published in Chest (01-06-2020)Get full text
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Nintedanib and Sildenafil in Patients with Idiopathic Pulmonary Fibrosis. Echoes of the Past, Lessons for the Future
Published in American journal of respiratory and critical care medicine (15-12-2019)“…Nathan reflects on the study by Behr and colleagues on the INSTAGE cohort, categorized by the presence or absence of echocardiographic evidence of right heart…”
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Pulmonary hypertension in interstitial lung disease: screening, diagnosis and treatment
Published in Current opinion in pulmonary medicine (01-09-2021)“…Purpose of review Pulmonary vascular disease resulting in pulmonary hypertension in the context of interstitial lung disease (PH-ILD) is a common complication…”
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High-Flow Nasal Cannula Therapy in COVID-19: Using the ROX Index to Predict Success
Published in Respiratory care (01-06-2021)“…Optimal timing of mechanical ventilation in COVID-19 is uncertain. We sought to evaluate outcomes of delayed intubation and examine the ROX index (ie,…”
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Inhaled Treprostinil in Group 3 Pulmonary Hypertension. Reply
Published in The New England journal of medicine (13-05-2021)Get full text
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The Value and Application of the 6-Minute-Walk Test in Idiopathic Pulmonary Fibrosis
Published in Annals of the American Thoracic Society (01-01-2018)“…The 6-minute-walk test is a commonly used assessment of performance ability in a variety of cardiopulmonary diseases. It provides important functional…”
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Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs
Published in PloS one (11-03-2020)“…The Wnt/β-catenin signaling pathway has been implicated in human proliferative diseases such as cancer and fibrosis. The functions of β-catenin and several…”
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Efficacy of Inhaled Treprostinil on Multiple Disease Progression Events in Patients with Pulmonary Hypertension due to Parenchymal Lung Disease in the INCREASE Trial
Published in American journal of respiratory and critical care medicine (15-01-2022)“…The INCREASE study of inhaled treprostinil met its primary endpoint of change in 6-minute-walk distance at Week 16. In addition, there were significantly fewer…”
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Long-term Course and Prognosis of Idiopathic Pulmonary Fibrosis in the New Millennium
Published in Chest (01-07-2011)“…The American Thoracic Society and European Respiratory Society guidelines for the diagnosis and treatment of idiopathic pulmonary fibrosis (IPF) have been…”
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Lung Transplantation for Patients With COVID-19
Published in Chest (01-01-2022)“…The COVID-19 pandemic has caused acute lung injury in millions of individuals worldwide. Some patients develop COVID-related acute respiratory distress…”
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Treatment of Idiopathic Pulmonary Fibrosis With Ambrisentan: A Parallel, Randomized Trial
Published in Annals of internal medicine (07-05-2013)“…Idiopathic pulmonary fibrosis (IPF) is characterized by formation and proliferation of fibroblast foci. Endothelin-1 induces lung fibroblast proliferation and…”
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Pirfenidone for idiopathic pulmonary fibrosis: analysis of pooled data from three multinational phase 3 trials
Published in The European respiratory journal (01-01-2016)“…Pirfenidone is an antifibrotic agent that has been evaluated in three multinational phase 3 trials in patients with idiopathic pulmonary fibrosis (IPF). We…”
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The Future of Lung Transplantation
Published in Chest (01-02-2015)“…Lung transplantation has been the last of the solid organs to gain traction as a viable therapeutic option. Due to differing standards of care and the…”
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