Search Results - "NASH, G. B."

Identification and angiogenic role of the novel tumor endothelial marker CLEC14A by Mura, M, Swain, R K, Zhuang, X, Vorschmitt, H, Reynolds, G, Durant, S, Beesley, J F J, Herbert, J M J, Sheldon, H, Andre, M, Sanderson, S, Glen, K, Luu, N-T, McGettrick, H M, Antczak, P, Falciani, F, Nash, G B, Nagy, Z S, Bicknell, R

“…Tumor endothelial markers (TEMs) that are highly expressed in human tumor vasculature compared with vasculature in normal tissue hold clear therapeutic…”
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Kaposi's Sarcoma-Associated Herpesvirus Inhibits Expression and Function of Endothelial Cell Major Histocompatibility Complex Class II via Suppressor of Cytokine Signaling 3 by BUTLER, L. M, JEFFERY, H. C, WHEAT, R. L, LONG, H. M, RAE, P. C, NASH, G. B, BLACKBOURN, D. J

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Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Inhibits Neutrophil Recruitment through an Interleukin-6-Dependent Mechanism: a New Paradigm for Viral Immune Evasion by BUTLER, L. M, JEFFERY, H. C, WHEAT, R. L, RAE, P. C, TOWNSEND, K, ALKHARSAH, K. R, SCHULZ, T. F, NASH, G. B, BLACKBOURN, D. J

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A stromal address code defined by fibroblasts by Parsonage, Greg, Filer, Andrew D., Haworth, Oliver, Nash, Gerard B., Rainger, G. Ed, Salmon, Michael, Buckley, Christopher D.

“…To navigate into and within tissues, leukocytes require guidance cues that enable them to recognize which tissues to enter and which to avoid. Such cues are…”
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Comparison of the pro-inflammatory potential of monocytes from healthy adults and those with peripheral arterial disease using an in vitro culture model by Luu, N.T, Madden, J, Calder, P.C, Grimble, R.F, Shearman, C.P, Chan, T, Tull, S.P, Dastur, N, Rainger, G.E, Nash, G.B

“…Abstract We adapted a monocyte:endothelial cell co-culture model to investigate the pro-inflammatory potential of monocytes from patients with peripheral…”
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Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells by Bruce, L J, Wrong, O, Toye, A M, Young, M T, Ogle, G, Ismail, Z, Sinha, A K, McMaster, P, Hwaihwanje, I, Nash, G B, Hart, S, Lavu, E, Palmer, R, Othman, A, Unwin, R J, Tanner, M J

“…We describe three mutations of the red-cell anion exchangerband 3 (AE1, SLC4A1) gene associated with distalrenal tubular acidosis (dRTA) in families from…”
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Endothelial-borne platelet-activating factor and interleukin-8 rapidly immobilize rolling neutrophils by Rainger, G E, Fisher, A C, Nash, G B

“…The kinetics of the response of integrins to activating signal(s) must be rapid to ensure that rolling neutrophils are localized at the sites of inflammation…”
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Adhesion of flowing neutrophils to cultured endothelial cells after hypoxia and reoxygenation in vitro by Rainger, G E, Fisher, A, Shearman, C, Nash, G B

“…Using a novel in-line deoxygenating system linked to an in vitro flow-based adhesion assay and video microscopy, we have studied neutrophil recruitment and…”
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Differential Binding of Clonal Variants of Plasmodium falciparum to Allelic Forms of Intracellular Adhesion Molecule 1 Determined by Flow Adhesion Assay by ADAMS, S, TURNER, G. D. H, NASH, G. B, MICKLEM, K, NEWBOLD, C. I, CRAIG, A. G

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Role of the cytoskeleton in rapid activation of CD11b/CD18 function and its subsequent downregulation in neutrophils by Anderson, S I, Hotchin, N A, Nash, G B

“…When rolling adherent neutrophils are stimulated, they rapidly immobilize through activation of integrin CD11b/CD18, and then modulate attachment through this…”
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Rolling and stationary cytoadhesion of red blood cells parasitized by Plasmodium falciparum: separate roles for ICAM-1, CD36 and thrombospondin by Cooke, B M, Berendt, A R, Craig, A G, MacGregor, J, Newbold, C I, Nash, G B

“…Adhesion of parasitized erythrocytes to microvascular endothelium is a central event in the pathogenesis of severe falciparum malaria. We have characterized…”
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Selectin-Mediated Rolling of Neutrophils on Immobilized Platelets by Buttrum, Stephen M., Hatton, Raymond, Nash, Gerard B.

“…Interaction between neutrophils and platelets at the site of vascular damage or in ischaemic tissue may promote thrombosis and/or vascular occlusion. To study…”
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Multiple adhesive phenotypes linked to rosetting binding of erythrocytes in Plasmodium falciparum malaria by FERNANDEZ, V, TREUTIGER, C. J, NASH, G. B, WAHLGREN, M

“…The cerebral form of severe malaria is associated with excessive intravascular sequestration of Plasmodium falciparum-infected erythrocytes (PRBC). Retention…”
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Effects of fluorescent dyes on selectin and integrin-mediated stages of adhesion and migration of flowing leukocytes by Abbitt, Katherine B, Rainger, G.Ed, Nash, Gerard B

“…Fluorescent dyes assist visualisation of leukocytes for intravital studies of adhesion or for in vitro studies utilising whole blood. We have used in vitro…”
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Natural Protection Against Severe Plasmodium falciparum Malaria Due to Impaired Rosette Formation by Carlson, Johan, Nash, Gerard B., Gabutti, Vilma, Al-Yaman, Fadwa, Wahlgren, Mats

“…Genes for two lethal diseases, thalassemia and sickle cell anemia, are favored by evolution because, in their heterozygous form, they protect against cerebral…”
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Perturbation of Red Blood Cell Membrane Rigidity by Extracellular Ligands by Paulitschke, M., Nash, G.B., Anstee, D.J., Tanner, M.J.A., Gratzer, W.B.

“…It is known that binding of extracellular antibodies against the major sialoglycoprotein, glycophorin A, reduces the deformability of the red blood cell…”
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Rheological Analysis of the Adhesive Interactions of Red Blood Cells Parasitized by Plasmodium falciparum by Nash, G.B., Cooke, B.M., Marsh, K., Berendt, A., Newbold, C., Stuart, J.

“…Adhesion of parasitized red blood cells (RBCs) to vascular endothelium is thought to be a key factor in the pathology of falciparum malaria. However,…”
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Adhesion between neutrophils and platelets: a modulator of thrombotic and inflammatory events? by Nash, G B

“…Recent studies have demonstrated that neutrophilic granulocytes and platelets have the capability to interact with each other. Either type of cell may release…”
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Rheological response of neutrophils to different types of stimulation by Buttrum, S M, Drost, E M, MacNee, W, Goffin, E, Lockwood, C M, Hatton, R, Nash, G B

“…The potential for neutrophils to obstruct microvessels was evaluated by measuring transit of individual neutrophils through 8-microns pores in an automated…”
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White cell accumulation in dependent legs of patients with venous hypertension: a possible mechanism for trophic changes in the skin by Thomas, P R S, Nash, G B, Dormandy, J A

“…The mechanism by which chronic venous insufficiency and venous hypertension are associated with ulceration of the legs is not yet understood. To investigate…”
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