Search Results - "NANASI, Peter P"

Dynamics of the late Na+ current during cardiac action potential and its contribution to afterdepolarizations by Horvath, Balazs, Banyasz, Tamas, Jian, Zhong, Hegyi, Bence, Kistamas, Kornel, Nanasi, Peter P, Izu, Leighton T, Chen-Izu, Ye

“…Abstract The objective of this work is to examine the contribution of late Na+ current ( INa,L ) to the cardiac action potential (AP) and arrhythmogenic…”
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Selective Na+/Ca2+ exchanger inhibition prevents Ca2+ overload‐induced triggered arrhythmias by Nagy, Norbert, Kormos, Anita, Kohajda, Zsófia, Szebeni, Áron, Szepesi, Judit, Pollesello, Piero, Levijoki, Jouko, Acsai, Károly, Virág, László, Nánási, Péter P, Papp, Julius Gy, Varró, András, Tóth, András

“…Background and Purpose Augmented Na+/Ca2+ exchanger (NCX) activity may play a crucial role in cardiac arrhythmogenesis; however, data regarding the…”
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Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium by SZENTADRASSY, Norbert, BANYASZ, Tamas, BIRO, Tamas, SZABO, Gergely, TOTH, Balazs I, MAGYARA, Janos, LAZAR, Jozsef, VARRO, Andras, KOVACS, Laszlo, NANASI, Peter P

“…The aim of the present study was to compare the apico-basal distribution of ion currents and the underlying ion channel proteins in canine and human…”
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Potential therapeutic effects of Na+/Ca2+ exchanger inhibition in cardiac diseases by Tóth, András, Kiss, Loránd, Varró, András, Nánási, Péter P

“…The Na+/Ca2+ exchanger (NCX) has a pivotal role in cardiac Na+ and Ca2+ homeostasis and is an essential pathway for Ca2+ extrusion from cardiomyocytes. Altered…”
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Antiarrhythmic and Inotropic Effects of Selective Na+/Ca2+ Exchanger Inhibition: What Can We Learn from the Pharmacological Studies? by Nagy, Norbert, Tóth, Noémi, Nánási, Péter P.

“…Life-long stable heart function requires a critical balance of intracellular Ca2+. Several ion channels and pumps cooperate in a complex machinery that…”
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Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs by Jost, Norbert, Virág, László, Comtois, Philippe, Ördög, Balázs, Szuts, Viktória, Seprényi, György, Bitay, Miklós, Kohajda, Zsófia, Koncz, István, Nagy, Norbert, Szél, Tamás, Magyar, János, Kovács, Mária, Puskás, László G., Lengyel, Csaba, Wettwer, Erich, Ravens, Ursula, Nánási, Péter P., Papp, Julius Gy, Varró, András, Nattel, Stanley

“…Key points •  Cardiac repolarization, through which heart‐cells return to their resting state after having fired, is a delicate process, susceptible to…”
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A Multiscale Investigation of Repolarization Variability and Its Role in Cardiac Arrhythmogenesis by Pueyo, Esther, Corrias, Alberto, Virág, László, Jost, Norbert, Szél, Tamás, Varró, András, Szentandrássy, Norbert, Nánási, Péter P., Burrage, Kevin, Rodríguez, Blanca

“…Enhanced temporal and spatial variability in cardiac repolarization has been related to increased arrhythmic risk both clinically and experimentally. Causes…”
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Calcium Handling Defects and Cardiac Arrhythmia Syndromes by Kistamás, Kornél, Veress, Roland, Horváth, Balázs, Bányász, Tamás, Nánási, Péter P, Eisner, David A

“…Calcium ions (Ca ) play a major role in the cardiac excitation-contraction coupling. Intracellular Ca concentration increases during systole and falls in…”
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Relationship between ion currents and membrane capacitance in canine ventricular myocytes by Horváth, Balázs, Kovács, Zsigmond, Dienes, Csaba, Barta, Zalán, Óvári, József, Szentandrássy, Norbert, Magyar, János, Bányász, Tamás, Nánási, Péter P.

“…Current density, the membrane current value divided by membrane capacitance (C m ), is widely used in cellular electrophysiology. Comparing current densities…”
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Late Sodium Current Inhibitors as Potential Antiarrhythmic Agents by Horváth, Balázs, Hézső, Tamás, Kiss, Dénes, Kistamás, Kornél, Magyar, János, Nánási, Péter P, Bányász, Tamás

“…Based on recent findings, an increased late sodium current (I ) plays an important pathophysiological role in cardiac diseases, including rhythm disorders. The…”
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Astrocyte- and NMDA receptor-dependent slow inward currents differently contribute to synaptic plasticity in an age-dependent manner in mouse and human neocortex by Csemer, Andrea, Kovács, Adrienn, Maamrah, Baneen, Pocsai, Krisztina, Korpás, Kristóf, Klekner, Álmos, Szücs, Péter, Nánási, Péter P, Pál, Balázs

“…Slow inward currents (SICs) are known as excitatory events of neurons elicited by astrocytic glutamate via activation of extrasynaptic NMDA receptors. By using…”
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Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth by Borbíró, István, Lisztes, Erika, Tóth, Balázs I., Czifra, Gabriella, Oláh, Attila, Szöllősi, Attila G., Szentandrássy, Norbert, Nánási, Péter P., Péter, Zoltán, Paus, Ralf, Kovács, László, Bíró, Tamás

“…In the current study, we aimed at identifying the functional role of transient receptor potential vanilloid-3 (TRPV3) ion channel in the regulation of human…”
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Therapeutic Approaches of Ryanodine Receptor-Associated Heart Diseases by Szentandrássy, Norbert, Magyar, Zsuzsanna É, Hevesi, Judit, Bányász, Tamás, Nánási, Péter P, Almássy, János

“…Cardiac diseases are the leading causes of death, with a growing number of cases worldwide, posing a challenge for both healthcare and research. Therefore, the…”
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Safety Concerns of Diamide Insecticides by Almássy, János, Csernoch, László, Nánási, Péter P

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TRPM4 links calcium signaling to membrane potential in pancreatic acinar cells by Diszházi, Gyula, Magyar, Zsuzsanna É., Lisztes, Erika, Tóth-Molnár, Edit, Nánási, Péter P., Vennekens, Rudi, Tóth, Balázs I., Almássy, János

“…Transient receptor potential cation channel subfamily M member 4 (TRPM4) is a Ca2+-activated nonselective cation channel that mediates membrane depolarization…”
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The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments by Kohajda, Zsófia, Farkas-Morvay, Nikolett, Jost, Norbert, Nagy, Norbert, Geramipour, Amir, Horváth, András, Varga, Richárd S, Hornyik, Tibor, Corici, Claudia, Acsai, Károly, Horváth, Balázs, Prorok, János, Ördög, Balázs, Déri, Szilvia, Tóth, Dániel, Levijoki, Jouko, Pollesello, Piero, Koskelainen, Tuula, Otsomaa, Leena, Tóth, András, Baczkó, István, Leprán, István, Nánási, Péter P, Papp, Julius Gy, Varró, András, Virág, László

“…In this study the effects of a new, highly selective sodium-calcium exchanger (NCX) inhibitor, ORM-10962 were investigated on cardiac NCX current, Ca2+…”
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Ion current profiles in canine ventricular myocytes obtained by the “onion peeling” technique by Horváth, Balázs, Kiss, Dénes, Dienes, Csaba, Hézső, Tamás, Kovács, Zsigmond, Szentandrássy, Norbert, Almássy, János, Magyar, János, Bányász, Tamás, Nánási, Péter P.

“…The profiles of ion currents during the cardiac action potential can be visualized by the action potential voltage clamp technique. To obtain multiple ion…”
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Editorial: Perspectives of Antiarrhythmic Drug Therapy: Disappointing Past, Current Efforts, and Faint Hopes by Nánási, Péter P., Pueyo, Esther, Virág, László

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Beat-to-beat variability of cardiac action potential duration: underlying mechanism and clinical implications by Nánási, Péter P, Magyar, János, Varró, András, Ördög, Balázs

“…Beat-to-beat variability of cardiac action potential duration (short-term variability, SV) is a common feature of various cardiac preparations, including the…”
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Electrophysiological Effects of the Transient Receptor Potential Melastatin 4 Channel Inhibitor (4-Chloro-2-(2-chlorophenoxy)acetamido) Benzoic Acid (CBA) in Canine Left Ventricular Cardiomyocytes by Dienes, Csaba, Hézső, Tamás, Kiss, Dénes Zsolt, Baranyai, Dóra, Kovács, Zsigmond Máté, Szabó, László, Magyar, János, Bányász, Tamás, Nánási, Péter P., Horváth, Balázs, Gönczi, Mónika, Szentandrássy, Norbert

“…Transient receptor potential melastatin 4 (TRPM4) plays an important role in many tissues, including pacemaker and conductive tissues of the heart, but much…”
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