Search Results - "NAM, R. K"

The impact of a BRCA2 mutation on mortality from screen-detected prostate cancer by Akbari, M R, Wallis, C J D, Toi, A, Trachtenberg, J, Sun, P, Narod, S A, Nam, R K

“…Background: Men with a BRCA2 mutation face an increased risk of prostate cancer. These cancers tend to have an aggressive nature and it has not yet been…”
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Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer by NAM, R. K, SUGAR, L, TRACHTENBERG, J, NAROD, S. A, SETH, A, YANG, W, SRIVASTAVA, S, KLOTZ, L. H, YANG, L-Y, STANIMIROVIC, A, ENCIOIU, E, NEILL, M, LOBLAW, D. A

“…The prostate-specific gene, TMPRSS2 is fused with the gene for the transcription factor ERG in a large proportion of human prostate cancers. The prognostic…”
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Adverse event profile for immunotherapy agents compared with chemotherapy in solid organ tumors: a systematic review and meta-analysis of randomized clinical trials by Magee, D.E., Hird, A.E., Klaassen, Z., Sridhar, S.S., Nam, R.K., Wallis, C.J.D., Kulkarni, G.S.

“…Immunotherapy agents are an innovative oncological treatment modality and as a result their use has expanded widely. Understanding the treatment-related…”
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Prevalence and patterns of the use of complementary therapies among prostate cancer patients: an epidemiological analysis by Nam, R K, Fleshner, N, Rakovitch, E, Klotz, L, Trachtenberg, J, Choo, R, Morton, G, Danjoux, C

“…We determine the prevalence and patterns of the use of complementary therapies among patients with and those at high risk for prostate cancer. A…”
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Complications following surgery with or without radiotherapy or radiotherapy alone for prostate cancer by Wallis, C J D, Cheung, P, Herschorn, S, Saskin, R, Su, J, Klotz, L H, Kulkarni, G S, Lee, Y, Kodama, R T, Narod, S A, Nam, R K

“…Background: Men undergoing treatment of clinically localised prostate cancer may experience a number of treatment-related complications, which affect their…”
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V89L polymorphism of type-2, 5-alpha reductase enzyme gene predicts prostate cancer presence and progression by Nam, R.K, Toi, A, Vesprini, D, Ho, M, Chu, W, Harvie, S, Sweet, J, Trachtenberg, J, Jewett, M.A.S, Narod, S.A

“…Objectives. The valine (V) to leucine (L) polymorphism of the SRD5A2 gene is associated with 5-alpha reductase-2 activity; patients with the V allele have high…”
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MicroRNAs in prostate cancer: from biomarkers to molecularly-based therapeutics by Gordanpour, A, Nam, R K, Sugar, L, Seth, A

“…MicroRNAs (miRNAs) are effective regulators of gene expression that have a significant role in the pathogenesis of prostate and various other cancers. The high…”
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Serum Human Glandular Kallikrein-2 Protease Levels Predict the Presence of Prostate Cancer Among Men With Elevated Prostate-Specific Antigen by NAM, R. K, DIAMANDIS, E. P, TOI, A, TRACHTENBERG, J, MAGKLARA, A, SCORILAS, A, PAPNASTASIOU, P. A, JEWETT, M. A. S, NAROD, S. A

“…We hypothesize that serum human glandular kallikrein-2 (hK2) levels predict the presence of prostate cancer among men prescreened by prostate-specific antigen…”
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Significance of the CAG repeat polymorphism of the androgen receptor gene in prostate cancer progression by Nam, R K, Elhaji, Y, Krahn, M D, Hakimi, J, Ho, M, Chu, W, Sweet, J, Trachtenberg, J, Jewett, M A, Narod, S A

“…The CAG repeat polymorphism of the androgen receptor gene has been associated with an increased prostate cancer risk, and the repeat length correlated with…”
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A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer by Nam, R K, Zhang, W W, Loblaw, D A, Klotz, L H, Trachtenberg, J, Jewett, M A S, Stanimirovic, A, Davies, T O, Toi, A, Venkateswaran, V, Sugar, L, Siminovitch, K A, Narod, S A

“…We conducted a genome-wide association study of 3090 sporadic prostate cancer patients and controls using the Affymetrix 10 000 SNP GeneChip. Initial screening…”
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Prostate specific antigen velocity as a measure of the natural history of prostate cancer: defining a ‘rapid riser’ subset by NAM, R. K, KLOTZ, L. H, JEWETT, M. A. S, DANJOUX, C, TRACHTENBERG, J

“…Objective  To study the rate of change in prostate specific antigen (PSA velocity) in patients with prostate cancer initially managed by ‘watchful waiting’…”
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Influence of initial semen quality on the integrity of human sperm DNA following semen processing by Zini, A, Nam, R K, Mak, V, Phang, D, Jarvi, K

“…To examine and compare the effects of density-gradient centrifugation on the integrity of sperm DNA from the semen of both fertile and infertile men…”
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HPC2 Variants and Screen-Detected Prostate Cancer by Vesprini, Danny, Nam, Robert K., Trachtenberg, John, Jewett, Michael A.S., Tavtigian, Sean V., Emami, Marjan, Ho, Minnie, Toi, Ants, Narod, Steven A.

“…Two studies have reported significant associations between susceptibility to prostate cancer and two common missense variants of the HPC2/ELAC2 gene, with…”
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Reply by Authors by Matta, R., Hird, A. E., Saskin, R., Radomski, S. B., Carr, L., Kodama, R. T., Nam, R. K., Herschorn, S.

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Comparison of molecular and conventional strategies for followup of superficial bladder cancer using decision analysis by Nam, R K, Redelmeier, D A, Spiess, P E, Sampson, H A, Fradet, Y, Jewett, M A

“…Patients with superficial bladder cancer require long-term surveillance for recurrence. We compared the cost of cystoscopy and cytology (standard care) to that…”
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Association Between Germline HOXB13 G84E Mutation and Risk of Prostate Cancer by AKBARI, Mohammad R, TRACHTENBERG, John, LEE, Justin, TAM, Stephanie, BRISTOW, Robert, LOBLAW, Andrew, NAROD, Steven A, NAM, Robert K

“…Recently, a G84E mutation in HOXB13, a gene involved in prostate development, was shown to be strongly associated with an increased risk of prostate cancer. To…”
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Relapse and cure rates of prostate cancer patients after radical prostatectomy and 5 years of follow-up by Vassilikos, Evyenia J.K., Yu, He, Trachtenberg, John, Nam, Robert K., Narod, Steven A., Bromberg, Irving L., Diamandis, Eleftherios P.

“…Objectives: We have compared the ability of an ultrasensitive prostate specific antigen assay and a regular PSA assay to identify relapse and cure rates of…”
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miR-221 Is Down-regulated in TMPRSS2:ERG Fusion-positive Prostate Cancer by GORDANPOUR, Aida, STANIMIROVIC, Aleksandra, NAM, Robert K, MORENO, Carlos S, SHERMAN, Christopher, SUGAR, Linda, SETH, Arun

“…Expression profiling studies using microarrays and other methods have shown that microRNAs (miRNAs) are dysregulated in a wide variety of human cancers. The…”
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Reply by Authors by Matta, R, Hird, A E, Saskin, R, Radomski, S B, Carr, L, Kodama, R T, Nam, R K, Herschorn, S

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Re: Is There an Association between Urinary Incontinence and Mortality? A Retrospective Cohort Study by Matta, R, Hird, A E, Saskin, R, Radomski, S B, Carr, L, Kodama, R T, Nam, R K, Herschorn, S

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