Search Results - "NAKAZAWA, S"
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Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
Published in Clinical cancer research (15-11-2013)“…Neuroblastoma is a pediatric cancer that continues to exact significant morbidity and mortality. Recently, a number of cell-cycle proteins, particularly those…”
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Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis
Published in Cancer discovery (01-10-2013)“…Intratumoral hypoxia and expression of hypoxia-inducible factor-1α (HIF-1α) correlate with metastasis and poor survival in patients with sarcoma. We show here…”
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An Extremely Low Methanol Crossover and Highly Durable Aromatic Pore-Filling Electrolyte Membrane for Direct Methanol Fuel Cells
Published in Advanced materials (Weinheim) (19-02-2007)“…A highly durable pore‐filling‐type electrolyte membrane for direct methanol fuel cells has been developed from a porous polyimide substrate and a wholly…”
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Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis
Published in Proceedings of the National Academy of Sciences - PNAS (30-06-2015)“…Genetic aberrations responsible for soft-tissue sarcoma formation in adults are largely unknown, with targeted therapies sorely needed for this complex and…”
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Scientific Objectives of Small Carry-on Impactor (SCI) and Deployable Camera 3 Digital (DCAM3-D): Observation of an Ejecta Curtain and a Crater Formed on the Surface of Ryugu by an Artificial High-Velocity Impact
Published in Space science reviews (01-07-2017)“…The Small Carry-on Impactor (SCI) equipped on Hayabusa2 was developed to produce an artificial impact crater on the primitive Near-Earth Asteroid (NEA) 162173…”
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Electric field control of magnetic anisotropy in a Co/Pt bilayer deposited on a high-κ SrTiO3
Published in Applied physics letters (06-02-2017)“…The perpendicular magnetic anisotropy (PMA) of a Co (0.5 nm)/Pt (2.4 nm) bilayer film was electrostatically tuned using a high-κ dielectric, SrTiO3, with a…”
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Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth
Published in Nature communications (03-02-2016)“…In soft tissue sarcomas (STS), low intratumoural O 2 (hypoxia) is a poor prognostic indicator. HIF-1α mediates key transcriptional responses to hypoxia, and…”
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Plasmodium knowlesi and human malaria parasites in Khan Phu, Vietnam: Gametocyte production in humans and frequent co-infection of mosquitoes
Published in Parasitology (01-04-2017)“…Four species of malaria parasite, Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae and Plasmodium knowlesi infect humans living in the Khanh Phu…”
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MYC Degradation under Low O2 Tension Promotes Survival by Evading Hypoxia-Induced Cell Death
Published in Molecular and Cellular Biology (01-09-2013)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability
Published in Blood (21-05-2015)“…Hypoxia-inducible factors (HIFs) are master regulators of the transcriptional response to low oxygen and play essential roles in embryonic development, tissue…”
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Particle size distributions inside and around the artificial crater produced by the Hayabusa2 impact experiment on Ryugu
Published in Earth, planets, and space (17-10-2022)“…Japanese Hayabusa2 spacecraft has successfully carried out an impact experiment using a small carry-on impactor (SCI) on an asteroid (162173) Ryugu. We examine…”
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Ryugu’s Anhydrous Ingredients and Their Spectral Link to Primitive Dust from the Outer Solar System
Published in Astrophysical journal. Letters (01-07-2023)“…Abstract Ryugu is a second-generation C-type asteroid formed by the reassembly of fragments of a previous larger body in the main asteroid belt. While the…”
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A comprehensive study of apatite grains in Ryugu rock fragments
Published in Meteoritics & planetary science (01-08-2024)“…Apatite is present as an accessory phase in many meteorites and is often formed as a secondary product of aqueous alteration. Its propensity to incorporate…”
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MicroRNA-124 expression counteracts pro-survival stress responses in glioblastoma
Published in Oncogene (23-04-2015)“…Glioblastomas are aggressive adult brain tumors, characterized by inadequately organized vasculature and consequent nutrient and oxygen (O 2 )-depleted areas…”
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Constraints on Solar System early evolution by MicrOmega analysis of Ryugu carbonates
Published in Nature astronomy (01-04-2023)“…The samples returned from a C-type asteroid (Ryugu) by the Hayabusa2 mission constitute unprecedented access to carbonaceous material never exposed to Earth’s…”
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Oxygen availability and metabolic adaptations
Published in Nature reviews. Cancer (01-10-2016)“…Key Points Tumour microenvironments harbour multiple microdomains whereby cells experience limited (and highly variable) access to oxygen and nutrients. Oxygen…”
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Functional Status of Centenarians in Tokyo, Japan: Developing Better Phenotypes of Exceptional Longevity
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-03-2006)“…Background. Centenarians are sometimes said to be representative of lifelong healthy aging. Whether they are, in fact, examples of healthy aging remains a…”
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IMPACT ON ABSORBED DOSE RATE IN AIR IN KANTO REGION BY FUKUSHIMA DAIICHI NUCLEAR POWER PLANT ACCIDENT
Published in Radiation protection dosimetry (01-10-2019)“…Abstract Absorbed dose rates in air were measured for the whole area of the Kanto region in 2015, 2016 and 2017 (n = 31 147). The mean absorbed dose rates in…”
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Simulation of Seismic Wave Propagation on Asteroid Ryugu Induced by The Impact Experiment of The Hayabusa2 Mission: Limited Mass Transport by Low Yield Strength of Porous Regolith
Published in Journal of geophysical research. Planets (01-02-2021)“…Seismic shaking has been regarded as an essential source of resurfacing on asteroids. The Small Carry‐on Impactor (SCI) operation on Hayabusa2 has been…”
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