Search Results - "NAKAYAMA, Tetsuo"

An inflammatory response is essential for the development of adaptive immunity-immunogenicity and immunotoxicity by Nakayama, Tetsuo

“…Highlights • All effective vaccines stimulate innate immunity with induction of cytokines. • G-CSF was produced three hours after vaccination in muscle…”
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Vaccine chronicle in Japan by Nakayama, Tetsuo

“…Abstract The concept of immunization was started in Japan in 1849 when Jenner’s cowpox vaccine seed was introduced, and the current immunization law was…”
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Comparison of cytokine production in mice inoculated with messenger RNA vaccines BNT162b2 and mRNA‐1273 by Nakayama, Tetsuo, Sawada, Akihito, Ito, Takeshi

“…Two messenger RNA (mRNA) vaccines of BNT162b2 and mRNA‐1273 were licensed. The most common adverse event is regional pain at the injection site in 80%. As…”
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Long‐term regulation of local cytokine production following immunization in mice by Nakayama, Tetsuo, Kashiwagi, Yasuyo, Kawashima, Hisashi

“…ABSTRACT Vaccines based on pathogen components require adjuvants to enhance the antigen‐specific adaptive immune response. Intramuscular injection of…”
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Trisaccharide containing α2,3-linked sialic acid is a receptor for mumps virus by Kubota, Marie, Takeuchi, Kaoru, Watanabe, Shumpei, Ohno, Shinji, Matsuoka, Rei, Kohda, Daisuke, Nakakita, Shin-ichi, Hiramatsu, Hiroaki, Suzuki, Yasuo, Nakayama, Tetsuo, Terada, Tohru, Shimizu, Kentaro, Shimizu, Nobutaka, Shiroishi, Mitsunori, Yanagi, Yusuke, Hashiguchi, Takao

“…Mumps virus (MuV) remains an important pathogen worldwide, causing epidemic parotitis, orchitis, meningitis, and encephalitis. Here we show that MuV…”
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Experimental animal model for analyzing immunobiological responses following vaccination with formalin-inactivated respiratory syncytial virus by Sawada, Akihito, Nakayama, Tetsuo

“…ABSTRACT Formalin‐inactivated respiratory syncytial virus (FI‐RSV) vaccine was developed in the 1960s. However, this vaccine does not prevent infection in…”
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Cytokine and Chemokine Production in Mice Inoculated with NVX-CoV2373 (Nuvaxovid®) in Comparison with Omicron BA.4/5 Bivalent BNT162b2 (Comirnaty®) by Nakayama, Tetsuo, Ito, Takashi, Ishiyama, Ryoka, Katayama, Kazuhiko

“…A recombinant SARS-CoV-2 spike protein vaccine (NVX-CoV2373) has been licensed and has a lesser incidence of adverse events. To know the immunological…”
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Development of Acquired Immunity following Repeated Respiratory Syncytial Virus Infections in Cotton Rats by Yamaji, Yoshiaki, Yasui, Yosuke, Nakayama, Tetsuo

“…Respiratory syncytial virus (RSV) infections occur every year worldwide. Most infants are infected with RSV by one year of age and are reinfected because…”
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Booster vaccination using bivalent DS-5670a/b is safe and immunogenic against SARS-CoV-2 variants in children aged 5-11 years: a phase 2/3, randomized, active-controlled study by Suzuki, Rino, Suda, Miharu, Ishida, Katsuyasu, Furihata, Kei, Ota, Aisaku, Takahashi, Kaori, Sakakibara, Sachiko, Nakayama, Tetsuo, Takeshita, Fumihiko

“…DS-5670 is a messenger ribonucleic acid (mRNA) vaccine platform targeting the receptor-binding domain (RBD) of the spike protein derived from severe acute…”
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Recombinant Measles AIK-C Vaccine Strain Expressing the prM-E Antigen of Japanese Encephalitis Virus by Higuchi, Akira, Toriniwa, Hiroko, Komiya, Tomoyoshi, Nakayama, Tetsuo

“…An inactivated Japanese encephalitis virus (JEV) vaccine, which induces neutralizing antibodies, has been used for many years in Japan. In the present study,…”
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Vaccine adverse events reported in post-marketing study of the Kitasato Institute from 1994 to 2004 by Nakayama, Tetsuo, Onoda, Kazumasa

“…Abstract General physicians, pediatricians and parents realize that serious adverse events occur with an extremely rare incidence, but have no information on…”
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Immunogenicity of recombinant measles vaccine expressing fusion protein of respiratory syncytial virus in cynomolgus monkeys by Sawada, Akihito, Yunomae, Kiyokazu, Nakayama, Tetsuo

“…ABSTRACT Respiratory syncytial virus (RSV) is a common cause of respiratory infections in infants. Effective vaccines are currently being sought, but no…”
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Genomic diversity of mumps virus and global distribution of the 12 genotypes by Jin, Li, Örvell, Claes, Myers, Richard, Rota, Paul A., Nakayama, Tetsuo, Forcic, Dubravko, Hiebert, Joanne, Brown, Kevin E.

“…Summary The WHO recently proposed an updated nomenclature for mumps virus (MuV). WHO currently recognizes 12 genotypes of MuV, assigned letters from A to N…”
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Increased Production of Inflammatory Cytokines after Inoculation with Recombinant Zoster Vaccine in Mice by Nakayama, Tetsuo, Sawada, Akihito, Ito, Takeshi

“…Increasing numbers of patients with zoster were reported recently, and recombinant zoster vaccine (Shingrix®) was licensed using the AS01B adjuvant system…”
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Persistence of Antibodies against Diphtheria, Tetanus, Pertussis, and Poliovirus Types I, II, and III Following Immunization with DTaP Combined with Inactivated Wild-Type Polio Vaccine (DTaP-wIPV) by Nakayama, Tetsuo, Suga, Shigeru, Okada, Kenji, Okabe, Nobuhiko

“…A follow-up serological study was conducted involving 47 subjects who received 4 doses of diphtheria and tetanus toxoids, combined with the acellular pertussis…”
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Vaccine acquired pertussis immunity was weakened at 4 years of age and asymptomatic pertussis infection was suspected based on serological surveillance by Nakayama, Tetsuo, Suzuki, Eitaro, Noda, Atsuya

“…Serological surveillance of pertussis antibodies was performed in 118 children aged 1–12 years. The positivity of pertussis toxin (PT) antibodies was low at…”
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Epidemiological study on Japanese encephalitis virus distribution in Ishikawa prefecture, Japan, by serological investigation using wild boar sera by KOMIYA, Tomoyoshi, TORINIWA, Hiroko, MATSUMURA, Takahiro, TAKEGAMI, Tsutomu, NAKAYAMA, Tetsuo

“…Thirty-seven specimens of wild boar sera were collected from August 2016 to March 2018 in Ishikawa prefecture, Japan. Thirty-two specimens (86.5%) were…”
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Clinical Features and Characteristics of Hand, Foot, and Mouth Disease Caused by Recent Coxsackievirus A6: Five Cases in Japan from 2019 to 2022 by Naomiya, Kyohei, Ito, Takashi, Saito, Ayumi, Igarashi, Tsukasa, Nakayama, Tetsuo, Katayama, Kazuhiko, Ishikura, Kenji

“…Hand, foot, and mouth disease (HFMD) is a common infectious disease caused by enteroviruses. Coxsackievirus A6 (CV-A6)-associated HFMD has recently emerged as…”
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Persistence of Immunity Acquired after a Single Dose of Rubella Vaccine in Japan by Okafuji, Takao, Okafuji, Teruo, Nakayama, Tetsuo

“…To date, Takahashi, Matsuura, and TO-336 strains of live-attenuated rubella vaccine have been used in Japan. Japan implemented a single-dose rubella…”
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Appropriate Needle Length Determined by Ultrasonic Echography for Intramuscular Injection in Japanese Elderly over 50 Years by Nakayama, Tetsuo, Sekino, Hisakuni, Aihara, Hirokazu, Kino, Minoru

“…Adjuvanted vaccines are administered through intramuscular injection. To perform appropriate injection using an appropriate needle in different age groups or…”
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