Search Results - "NAKATA, Tadashi"

Total Synthesis of Marine Polycyclic Ethers by Nakata, Tadashi

“…Since the first isolation of BTX-B in 1981, the unprecedented structure and potent bioactivity of marine polycyclic ethers have attracted much attention of…”
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SmI2-induced cyclizations and their applications in natural product synthesis by Nakata, Tadashi

“…Since the isolation of brevetoxin‐B, a red tide toxin, many bioactive marine natural products featuring synthetically challenging trans‐fused polycyclic ether…”
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Stereoselective Synthesis of trans-Fused 7,6,6,7-Membered Tetracyclic Ether, Corresponding to the EFGH-Ring of Gambierol and the BCDE-Ring of Gambieric Acids by Saito, Tatsuo, Nakata, Tadashi

“…Stereoselective synthesis of a trans-fused 7,6,6,7-membered tetracyclic ether, corresponding to the EFGH-ring of gambierol and the BCDE-ring of gambieric…”
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C2-Symmetric Chiral Pentacyclic Guanidine: A Phase-Transfer Catalyst for the Asymmetric Alkylation of tert-Butyl Glycinate Schiff Base by Kita, Tetsuya, Georgieva, Angelina, Hashimoto, Yuichi, Nakata, Tadashi, Nagasawa, Kazuo

“…The enantioselective alkylation of the Schiff base 2 was carried out in the presence of a novel phase‐transfer catalyst, the guanidine‐containing pentacyclic…”
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Synthetic Studies on Maitotoxin. 1. Stereoselective Synthesis of the C′D′E′F′-Ring System Having a Side Chain by Morita, Masayuki, Ishiyama, Seishi, Koshino, Hiroyuki, Nakata, Tadashi

“…The stereoselective synthesis of the maitotoxin C′D′E′F′-ring system having a side chain has been accomplished through a convergent strategy. The key reactions…”
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Synthetic Studies on Maitotoxin. 2. Stereoselective Synthesis of the WXYZA′-Ring System by Morita, Masayuki, Haketa, Tasuku, Koshino, Hiroyuki, Nakata, Tadashi

“…The stereoselective synthesis of the WXYZA′-ring system of maitotoxin has been accomplished via a linear synthetic approach, in which key reactions were…”
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Discovery of novel antiviral agents directed against the influenza A virus nucleoprotein using photo-cross-linked chemical arrays by Hagiwara, Kyoji, Kondoh, Yasumitsu, Ueda, Atsushi, Yamada, Kazunori, Goto, Hideo, Watanabe, Toshiki, Nakata, Tadashi, Osada, Hiroyuki, Aida, Yoko

“…The nucleoprotein (NP) of the influenza virus is expressed in the early stage of infection and plays important roles in numerous steps of viral replication. NP…”
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Synthetic Studies on Maitotoxin. 3. Stereoselective Synthesis of the BCDE-Ring System by Satoh, Masanori, Koshino, Hiroyuki, Nakata, Tadashi

“…The stereoselective synthesis of the BCDE-ring system of maitotoxin has been accomplished through a two-directional strategy for the construction of polycyclic…”
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Pheromone Gland-Specific Fatty-Acyl Reductase of the Silkmoth, Bombyx mori by Moto, Ken'ichi, Yoshiga, Toyoshi, Yamamoto, Masanobu, Takahashi, Shunya, Okano, Kazuhiro, Ando, Tetsu, Nakata, Tadashi, Matsumoto, Shogo

“…The C10-C18unsaturated, acyclic, aliphatic compounds that contain an oxygenated functional group (alcohol, aldehyde, or acetate ester) are a major class of sex…”
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New synthetic method for 2,3- trans-2-methyl-tetrahydropyran-3-ol and oxepan-3-ol by unique insertion of a methyl group by Kimishima, Atsushi, Nakata, Tadashi

“…Treatment of tetrahydropyran-3-ol and oxepan-3-ol derivatives, which have a 1′-mesyloxy group at the C-2 side chain, with Me 3Al effected removal of the…”
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Stereoselective Synthesis of 2,6-syn-Dimethyl-tetrahydropyran Derivatives, Important Segments of Marine Polycyclic Ethers, by Unique Insertion of the Methyl Group by Maemoto, Michihiro, Kimishima, Atsushi, Nakata, Tadashi

“…Treatment of 6-methyl-tetrahydropyran derivatives, which have a 1′-mesyloxy group at the C2-side chain, with Me3Al effected stereoselective insertion of a…”
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Total Synthesis of an Antitumor Agent, Mucocin, Based on the “Chiron Approach” by Takahashi, Shunya, Nakata, Tadashi

“…The total synthesis of a powerful antitumor acetogenin, mucocin (1), was achieved through a palladium-catalyzed cross-coupling reaction of the THP−THF fragment…”
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Total Synthesis of the Proposed Structure for Pyragonicin by Takahashi, Shunya, Ogawa, Narihito, Koshino, Hiroyuki, Nakata, Tadashi

“…The total synthesis of acetogenin 1 reported for pyragonicin and its 10-epimer 32 is described. The common THP ring system was stereoselectively constructed…”
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Efficient strategy for the iterative synthesis of trans-fused polycyclic ether via SmI2-induced reductive intramolecular cyclization by Hori, Nobuyuki, Matsukura, Hiroko, Matsuo, Goh, Nakata, Tadashi

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Total Synthesis of a Cytotoxic Acetogenin, Pyranicin by Takahashi, Shunya, Kubota, Akemi, Nakata, Tadashi

“…The first total synthesis of a new cytotoxic acetogenin, pyranicin (1), is described. SmI2-induced reductive cyclization of β-alkoxy acrylate 4 proceeded…”
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Convergent Synthesis of the ABCDEF-Ring System of Yessotoxin and Adriatoxin by Suzuki, Keisuke, Nakata, Tadashi

“…The convergent synthesis of the ABCDEF-ring system of yessotoxin and adriatoxin was accomplished. This efficient convergent strategy was performed on the basis…”
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Stereoselective Synthesis of Maitotoxin GHI-Ring System Having a 1,2-Diol Side Chain by Nakata, Tadashi, Nagatomo, Masanori

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Efficient Synthesis of trans-Fused Polycyclic Ethers Including Tetrahydropyrans and Oxepanes Based on SmI2-Induced Reductive Cyclization by Hori, Nobuyuki, Matsukura, Hiroko, Nakata, Tadashi

“…An efficient method for the synthesis of trans-fused polycyclic ether ring systems including tetrahydropyrans and oxepanes, i.e., six−seven−six-,…”
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An efficient strategy for the iterative synthesis of a trans-fused polytetrahydropyran ring system via SmI2-induced reductive intramolecular cyclization by Hori, Nobuyuki, Matsukura, Hiroko, Matsuo, Goh, Nakata, Tadashi

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Stereoselective Syntheses of the C‘D‘E‘F‘-Ring System of Maitotoxin and the FG-Ring System of Gambierol by Sakamoto, Yasuharu, Matsuo, Goh, Matsukura, Hiroko, Nakata, Tadashi

“…The stereoselective syntheses of the C‘D‘E‘F‘-ring system of maitotoxin and the FG-ring system of gambierol were accomplished. The key steps involve…”
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