Search Results - "NAKANUMA, Yasuni"

A novel approach to biliary tract pathology based on similarities to pancreatic counterparts: Is the biliary tract an incomplete pancreas? by Nakanuma, Yasuni

“…There are peribiliary glands around the biliary tract, and these glands drain into the bile duct lumen. Interestingly, small amounts of pancreatic exocrine…”
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Pathologic classification of cholangiocarcinoma: New concepts by Nakanuma, Yasuni, MD, Kakuda, Yuko, MD

“…Abstract Herein, we propose a new pathologic classification of cholangiocarcinoma (CCA) based on recent progress in studies of preinvasive CCA lesions and the…”
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Interferon-induced protein with tetratricopeptide repeats 3 may be a key factor in primary biliary cholangitis by Sasaki, Motoko, Sato, Yasunori, Nakanuma, Yasuni

“…Accumulating studies suggest that senescent biliary epithelial cells (BECs) produce senescence-associated secretory phenotypes (SASPs) and play various roles…”
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Bile duct adenoma and small‐sized small duct type intrahepatic cholangiocarcinoma show distinct differences in genetic alterations, expression of IMP3 and EZH2 and stromal and inflammatory components by Sasaki, Motoko, Sato, Yasunori, Nakanuma, Yasuni

“…Aims Given that bile duct adenoma was significantly more prevalent in the liver with small duct type intrahepatic cholangiocarcinoma (small duct iCCA),…”
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Mutational landscape of combined hepatocellular carcinoma and cholangiocarcinoma, and its clinicopathological significance by Sasaki, Motoko, Sato, Yasunori, Nakanuma, Yasuni

“…Aims Combined hepatocellular carcinoma and cholangiocarcinoma (cHC‐CC), which generally has a poor prognosis, comprises hepatocellular carcinoma (HCC),…”
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KRAS and GNAS mutations and p53 overexpression in biliary intraepithelial neoplasia and intrahepatic cholangiocarcinomas by Hsu, Maylee, Sasaki, Motoko, Igarashi, Saya, Sato, Yasunori, Nakanuma, Yasuni

“…BACKGROUND: Similar to the pancreatic intraepithelial neoplasia (PanIN)‐pancreatic carcinoma sequence model, intrahepatic cholangiocarcinoma (ICC) also…”
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Pathological classification of intrahepatic cholangiocarcinoma based on a new concept by Nakanuma, Yasuni, Sato, Yasunori, Harada, Kenichi, Sasaki, Motoko, Xu, Jing, Ikeda, Hiroko

“…Intrahepatic cholangiocarcinoma (ICC) arises from the lining epithelium and peribiliary glands of the intrahepatic biliary tree and shows variable…”
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Th2 and regulatory immune reactions are increased in immunoglobin G4‐related sclerosing pancreatitis and cholangitis by Zen, Yoh, Fujii, Takahiko, Harada, Kenichi, Kawano, Mitsuhiro, Yamada, Kazunori, Takahira, Masayuki, Nakanuma, Yasuni

“…Immunoglobin G (IgG) 4‐related sclerosing pancreatitis and cholangitis (autoimmune pancreato‐cholangitis [AIPC]) are recently recognized disease entities…”
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A statement by the Japan‐Korea expert pathologists for future clinicopathological and molecular analyses toward consensus building of intraductal papillary neoplasm of the bile duct through several opinions at the present stage by Nakanuma, Yasuni, Jang, Kee‐Taek, Fukushima, Noriyoshi, Furukawa, Toru, Hong, Seung‐Mo, Kim, Haeryoung, Lee, Kyung Bun, Zen, Yoh, Jang, Jin‐Young, Kubota, Keiichi

“…Intraductal papillary neoplasm of bile duct (IPNB) was described as a preinvasive neoplastic lesion of the biliary tract in the 2010 World Health Organization…”
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Hepatocarcinogenesis: multistep changes of drainage vessels at CT during arterial portography and hepatic arteriography--radiologic-pathologic correlation by Kitao, Azusa, Zen, Yoh, Matsui, Osamu, Gabata, Toshifumi, Nakanuma, Yasuni

“…To clarify the changes that occur in drainage vessels of dysplastic nodules and hepatocellular carcinoma (HCC) during hepatocarcinogenesis by using computed…”
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Characterization of Intraductal Papillary Neoplasm of the Bile Duct with Respect to the Histopathologic Similarities to Pancreatic Intraductal Papillary Mucinous Neoplasm by Nakanuma, Yasuni, Kakuda, Yuko, Uesaka, Katsuhiko

“…Intraductal papillary neoplasms of the bile duct (IPNBs) are known to show various pathologic features and biological behaviors. Recently, two categories of…”
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Clinical diagnostic criteria of IgG4-related sclerosing cholangitis 2012 by Ohara, Hirotaka, Okazaki, Kazuichi, Tsubouchi, Hirohito, Inui, Kazuo, Kawa, Shigeyuki, Kamisawa, Terumi, Tazuma, Susumu, Uchida, Kazushige, Hirano, Kenji, Yoshida, Hitoshi, Nishino, Takayoshi, Ko, Shigeru B.H., Mizuno, Nobumasa, Hamano, Hideaki, Kanno, Atsushi, Notohara, Kenji, Hasebe, Osamu, Nakazawa, Takahiro, Nakanuma, Yasuni, Takikawa, Hajime

“…Background IgG4-sclerosing cholangitis (IgG4-SC) patients have an increased level of serum IgG4, dense infiltration of IgG4-positive plasma cells with…”
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Chemokine–Chemokine Receptor CCL2–CCR2 and CX3CL1–CX3CR1 Axis May Play a Role in the Aggravated Inflammation in Primary Biliary Cirrhosis by Sasaki, Motoko, Miyakoshi, Masami, Sato, Yasunori, Nakanuma, Yasuni

“…Background and Aims Senescent cells can alter local tissue environments by secretion of various senescence-associated secretory phenotypes (SASP), such as…”
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Bile Acids and Deregulated Cholangiocyte Autophagy in Primary Biliary Cholangitis by Sasaki, Motoko, Nakanuma, Yasuni

“…Primary biliary cholangitis (PBC) is characterized by a high prevalence of serum anti-mitochondrial antibodies against the E2 subunit of the pyruvate…”
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Pathologies of Precursor Lesions of Biliary Tract Carcinoma by Nakanuma, Yasuni, Kakuda, Yuko, Sugino, Takashi, Sato, Yasunori, Fukumura, Yuki

“…Carcinomas and precursor lesions of the biliary tract belong to a spectrum of pancreatobiliary neoplasms that share common histology and cell lineages. Over…”
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Polypoid invasive carcinoma of the gallbladder‐Another challenging polypoid neoplasm by Nakanuma, Yasuni, Sugino, Takashi, Nomura, Yoshikatsu, Watanabe, Hiroyuki, Terada, Takuro

“…Background Invasive gallbladder carcinoma generally presents as nodular‐sclerosing growth. Recently, “polypoid invasive carcinoma (PICA)” showing grossly…”
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Report of the 17th Nationwide Follow-up Survey of Primary Liver Cancer in Japan by Ikai, Iwao, Arii, Shigeki, Okazaki, Masatoshi, Okita, Kiwamu, Omata, Masao, Kojiro, Masamichi, Takayasu, Kenichi, Nakanuma, Yasuni, Makuuchi, Masatoshi, Matsuyama, Yutaka, Monden, Morito, Kudo, Masatoshi

“…In the 17th Nationwide Follow‐up Survey of Primary Liver Cancer in Japan, 18 213 individuals were newly registered as patients with primary liver cancer at 645…”
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Autophagy mediates the process of cellular senescence characterizing bile duct damages in primary biliary cirrhosis by Sasaki, Motoko, Miyakoshi, Masami, Sato, Yasunori, Nakanuma, Yasuni

“…Recent studies disclosed that autophagy is induced during and facilitates the process of senescence. Given that biliary epithelial cells (BECs) in damaged…”
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Classification of biliary tract cancers established by the Japanese Society of Hepato-Biliary-Pancreatic Surgery: 3rd English edition by Miyazaki, Masaru, Ohtsuka, Masayuki, Miyakawa, Shuichi, Nagino, Masato, Yamamoto, Masakazu, Kokudo, Norihiro, Sano, Keiji, Endo, Itaru, Unno, Michiaki, Chijiiwa, Kazuo, Horiguchi, Akihiko, Kinoshita, Hisafumi, Oka, Masaaki, Kubota, Keiichi, Sugiyama, Masanori, Uemoto, Shinji, Shimada, Mitsuo, Suzuki, Yasuyuki, Inui, Kazuo, Tazuma, Susumu, Furuse, Junji, Yanagisawa, Akio, Nakanuma, Yasuni, Kijima, Hiroshi, Takada, Tadahiro

“…The 3rd English edition of the Japanese classification of biliary tract cancers was released approximately 10 years after the 5th Japanese edition and the 2nd…”
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IgG4-related Lung and Pleural Disease: A Clinicopathologic Study of 21 Cases by YOH ZEN, INOUE, Dai, KITAO, Azusa, ONODERA, Manabu, ABO, Hitoshi, MIYAYAMA, Shiro, GABATA, Toshifumi, MATSUI, Osamu, NAKANUMA, Yasuni

“…Immunoglobulin G4 (IgG4)-related disorders can occur in the respiratory system. However, the clinicopathologic characteristics have not been well clarified. In…”
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