Search Results - "NAKANO, Toshiaki"

Atherosclerotic Diseases in Chronic Kidney Disease by Nakano, Toshiaki

“…Patients with chronic kidney disease (CKD) have a high incidence of atherosclerotic diseases, such as ischemic heart disease, cerebrovascular disease, and…”
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Role of Chronic Kidney Disease (CKD)–Mineral and Bone Disorder (MBD) in the Pathogenesis of Cardiovascular Disease in CKD by Yamada, Shunsuke, Nakano, Toshiaki

“…Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney disease (CKD). Multiple factors account for the increased incidence…”
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The Ankle–Brachial Index and Risk of Chronic Kidney Disease by Nakano, Toshiaki

“…Accumulating evidences have indicated that chronic kidney disease (CKD) is associated with increased risk of cardiovascular disease and death. Patients with…”
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Time to Shift our Mindset to a Phosphate-Centric Approach for Prevention of Cardiovascular Calcification in the Dialysis Population by Yamada, Shunsuke, Nakano, Toshiaki

“…[See article vol.30: 1568-1579] Cardiovascular disease is the leading cause of death in patients with chronic kidney disease (CKD). One of the major reasons…”
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Geriatric Nutritional Risk Index (GNRI) and Creatinine Index Equally Predict the Risk of Mortality in Hemodialysis Patients: J-DOPPS by Yamada, Shunsuke, Yamamoto, Shungo, Fukuma, Shingo, Nakano, Toshiaki, Tsuruya, Kazuhiko, Inaba, Masaaki

“…The geriatric nutritional risk index (GNRI) and creatinine (Cr) index are indexes often used as nutritional surrogates in patients receiving hemodialysis…”
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Low intake of β carotene and dietary fiber from vegetables and fruits in patients with chronic kidney disease by Nakano, Toshiaki, Tanaka, Shigeru, Tsuruya, Kazuhiko, Kitazono, Takanari

“…Patients with chronic kidney disease (CKD) occasionally need to restrict their consumption of vegetables and fruits. However, recent evidence suggests that…”
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Emerging cross-talks between chronic kidney disease–mineral and bone disorder (CKD–MBD) and malnutrition–inflammation complex syndrome (MICS) in patients receiving dialysis by Yamada, Shunsuke, Tsuruya, Kazuhiko, Kitazono, Takanari, Nakano, Toshiaki

“…Chronic kidney disease–mineral and bone disorder (CKD–MBD) is a systemic disorder that affects multiple organs and systems and increases the risk of morbidity…”
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Formation of clustered DNA damage in vivo upon irradiation with ionizing radiation: Visualization and analysis with atomic force microscopy by Nakano, Toshiaki, Akamatsu, Ken, Tsuda, Masataka, Tujimoto, Ayane, Hirayama, Ryoichi, Hiromoto, Takeshi, Tamada, Taro, Ide, Hiroshi, Shikazono, Naoya

“…SignificanceDNA damage causes loss of or alterations in genetic information, resulting in cell death or mutations. Ionizing radiations produce local, multiple…”
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Mechanisms of Tolerance Induction in Liver Transplantation: Lessons Learned from Fetomaternal Tolerance, Autoimmunity and Tumor Immunity by Nakano, Toshiaki, Goto, Shigeru, Chen, Chao-Long

“…Since the first published report of experimental kidney transplantation in dogs in 1902, there were many experimental and clinical trials of organ…”
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Causes of death in patients undergoing maintenance hemodialysis in Japan: 10-year outcomes of the Q-Cohort Study by Hiyamuta, Hiroto, Yamada, Shunsuke, Taniguchi, Masatomo, Nakano, Toshiaki, Tsuruya, Kazuhiko, Kitazono, Takanari

“…Background Although the mortality rate in patients on hemodialysis remains extremely high, detailed information on causes of death over long-term periods is…”
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Phosphate overload directly induces systemic inflammation and malnutrition as well as vascular calcification in uremia by Yamada, Shunsuke, Tokumoto, Masanori, Tatsumoto, Narihito, Taniguchi, Masatomo, Noguchi, Hideko, Nakano, Toshiaki, Masutani, Kosuke, Ooboshi, Hiroaki, Tsuruya, Kazuhiko, Kitazono, Takanari

“…Hyperphosphatemia contributes to increased cardiovascular mortality through vascular calcification (VC) in patients with chronic kidney disease (CKD)…”
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Association between Multimorbidity and Kidney Function among Patients with Non-Dialysis-Dependent CKD: The Fukuoka Kidney Disease Registry Study by Tanaka, Shigeru, Nakano, Toshiaki, Hiyamuta, Hiroto, Tsuruya, Kazuhiko, Kitazono, Takanari

“…Aim: Individuals with chronic kidney disease (CKD) have a high prevalence of comorbidities, including cardiovascular disease (CVD) and its risk factors…”
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Direct and indirect effects of fibroblast growth factor 23 on the heart by Nakano, Toshiaki, Kishimoto, Hiroshi, Tokumoto, Masanori

“…Fibroblast growth factor (FGF)23 is a bone-derived phosphotropic hormone that regulates phosphate and mineral homeostasis. Recent studies have provided…”
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SGLT2 inhibition mitigates transition from acute kidney injury to chronic kidney disease by suppressing ferroptosis by Hirashima, Yutaro, Nakano, Toshiaki, Torisu, Kumiko, Aihara, Seishi, Wakisaka, Masanori, Kitazono, Takanari

“…Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been shown to be renoprotective in ischemia-reperfusion (I/R) injury, with several proposed mechanisms,…”
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Radiation-induced DNA–protein cross-links: Mechanisms and biological significance by Nakano, Toshiaki, Xu, Xu, Salem, Amir M.H., Shoulkamy, Mahmoud I., Ide, Hiroshi

“…Ionizing radiation produces various DNA lesions such as base damage, DNA single-strand breaks (SSBs), DNA double-strand breaks (DSBs), and DNA–protein…”
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The Incidence and Associated Factors of Sudden Death in Patients on Hemodialysis: 10-Year Outcome of the Q-Cohort Study by Hiyamuta, Hiroto, Tanaka, Shigeru, Taniguchi, Masatomo, Tokumoto, Masanori, Fujisaki, Kiichiro, Nakano, Toshiaki, Tsuruya, Kazuhiko, Kitazono, Takanari

“…Aim: The incidence of sudden death and its risk factors in patients on hemodialysis remain unclear. This study aimed to clarify the incidence of sudden death…”
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Delta-Like Ligand 4-Notch Signaling in Macrophage Activation by Nakano, Toshiaki, Fukuda, Daiju, Koga, Jun-ichiro, Aikawa, Masanori

“…The Notch signaling pathway regulates the development of various cell types and organs, and also contributes to disease mechanisms in adults. Accumulating…”
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Clinical epidemiological analysis of cohort studies investigating the pathogenesis of kidney disease by Tanaka, Shigeru, Nakano, Toshiaki, Tsuruya, Kazuhiko, Kitazono, Takanari

“…In recent years, large cohort studies of patients with chronic kidney disease (CKD) have been established all over the world. These studies have attempted to…”
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Vascular endothelial growth factor-C ameliorates renal interstitial fibrosis through lymphangiogenesis in mouse unilateral ureteral obstruction by Hasegawa, Shoko, Nakano, Toshiaki, Torisu, Kumiko, Tsuchimoto, Akihiro, Eriguchi, Masahiro, Haruyama, Naoki, Masutani, Kosuke, Tsuruya, Kazuhiko, Kitazono, Takanari

“…Renal fibrosis is the final common pathway of chronic kidney diseases. Lymphatic vessel (LV) proliferation is found in human renal diseases and other fibrotic…”
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Arginase 2 is a mediator of ischemia-reperfusion injury in the kidney through regulation of nitrosative stress by Hara, Masatoshi, Torisu, Kumiko, Tomita, Keigo, Kawai, Yasuhiro, Tsuruya, Kazuhiko, Nakano, Toshiaki, Kitazono, Takanari

“…Kidney ischemia-reperfusion injury is a major cause of acute kidney injury (AKI). Following reduced kidney perfusion, the pathological overproduction of…”
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