Search Results - "NAKANISHI Megumi"

Efficacy and pharmacokinetics of ozoralizumab, an anti-TNFα NANOBODY ® compound, in patients with rheumatoid arthritis: 52-week results from the OHZORA and NATSUZORA trials by Takeuchi, Tsutomu, Chino, Yukihiro, Kawanishi, Masafumi, Nakanishi, Megumi, Watase, Hirotaka, Mano, Yoko, Sato, Yuri, Uchida, Saeko, Tanaka, Yoshiya

“…Ozoralizumab (OZR), a tumor necrosis factor alpha (TNFα) inhibitor, is a NANOBODY compound that binds to TNFα and human serum albumin. The main objective of…”
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Relevance of distinct monocyte subsets to clinical course of ischemic stroke patients by Kaito, Muichi, Araya, Shin-Ichi, Gondo, Yuichiro, Fujita, Michiyo, Minato, Naomi, Nakanishi, Megumi, Matsui, Makoto

“…The most common strategy for treating patients with acute ischemic stroke is thrombolytic therapy, though only a few patients receive benefits because of the…”
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Pregnancy‐induced hemorrhagic degeneration of adenomyosis by Nakanishi, Megumi, Iriyama, Takayuki, Sayama, Seisuke, Hanaoka, Shouhei, Toshimitsu, Masatake, Seyama, Takahiro, Sone, Kenbun, Kumasawa, Keiichi, Nagamatsu, Takeshi, Osuga, Yutaka

“…Uterine fibroids are known to degenerate during pregnancy, but it is unknown if similar pathologic condition occurs in adenomyosis. A 38‐year‐old para 1 woman…”
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Sporadic Late-onset Nemaline Myopathy Associated with Sjögren's Syndrome: A Case Report by Hamaguchi, Tsuyoshi, Nishino, Ichizo, Hirano, Yasuki, Uchida, Nobuaki, Fujita-Nakata, Michiyo, Nakanishi, Megumi, Sakai, Tomoyuki, Asahina, Masato

“…We report the case of a 46-year-old female patient who developed a subacute progression of axial and proximal muscle weakness. Laboratory findings revealed…”
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Systemic cellular immunity and neuroinflammation during acute flare-up in multiple sclerosis and neuromyelitis optica spectrum disorder patients by Uchida, Nobuaki, Mori, Kentaro, Fujita-Nakata, Michiyo, Nakanishi, Megumi, Sanada, Mitsuru, Nagayama, Shigemi, Sugiyama, Hiroshi, Matsui, Makoto

“…Twenty-seven treatment-naïve patients with relapsing-remitting multiple sclerosis (MS) and 13 with neuromyelitis optica spectrum disorder (NMOSD) were enrolled…”
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Rheumatoid meningitis developed in patient with stable rheumatoid arthritis and myasthenia gravis-detailed analysis of intracranial inflammation using flow cytometry by Oono, Miki, Fujita, Yoshimasa, Uchida, Nobuaki, Kawai, Ukichiro, Fujita-Nakata, Michiyo, Nakanishi, Megumi, Sanada, Mitsuru, Nagayama, Shigemi, Matsui, Makoto

“…Rheumatoid meningitis (RM) is a rare disorder that often develops during a remission phase of rheumatoid arthritis (RA). This is the first study to demonstrate…”
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Subclinical cancer cell dissemination in peritoneal lavage fluid detected by reverse-transcription polymerase chain reaction identifies patients at high risk for peritoneal recurrence and consequent impaired survival in the setting of preoperative chemoradiation therapy for pancreatic cancer by Takahashi, Hidenori, Akita, Hirofumi, Wada, Hiroshi, Tomokuni, Akira, Asukai, Kei, Takahashi, Yusuke, Yanagimoto, Yoshitomo, Matsunaga, Tomoyuki, Sugimura, Keijiro, Yamamoto, Kazuyoshi, Nishimura, Junichi, Yasui, Masayoshi, Omori, Takeshi, Miyata, Hiroshi, Yamamoto, Takashi, Nakanishi, Megumi, Shirayanagi, Maasa, Yamasaki, Tomoyuki, Ohue, Masayuki, Yano, Masahiko, Sakon, Masato, Ishikawa, Osamu

“…Preoperative chemoradiation therapy is a promising strategy for pancreatic cancer. Peritoneal recurrence is a major recurrence pattern after surgery for…”
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Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis by Satoh, Jun-ichi, Nakanishi, Megumi, Koike, Fumiko, Miyake, Sachiko, Yamamoto, Toshiyuki, Kawai, Mitsuru, Kikuchi, Seiji, Nomura, Kyouichi, Yokoyama, Kazumasa, Ota, Kohei, Kanda, Takashi, Fukazawa, Toshiyuki, Yamamura, Takashi

“…To clarify the molecular mechanisms underlying multiple sclerosis (MS)-promoting autoimmune process, we have investigated a comprehensive gene expression…”
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Relationship of systemic inflammation and cellular immunity with advancement of cognitive decline in patients with Alzheimer's disease by Kawai, Ukichiro, Uchida, Nobuaki, Oono, Miki, Fujita‐Nakata, Michiyo, Nakanishi, Megumi, Sanada, Mitsuru, Nagayama, Shigemi, Matsui, Makoto

“…Objective Systemic inflammation is known to be associated with Alzheimer's disease (AD) advancement. The aim of the present study was to examine the…”
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A Case of Single Hole Ileal Resection for Ascendiry Colon Cancer with Ureterocutaneous Fistula in the Right Lower Abdomen by Hayashi, Nobutaka, Nishizawa, Yujiro, Kagawa, Yoshinori, Inoue, Akira, Kawabe, Yusuke, Sindo, Miki, Suzuki, Ken, Nakanishi, Megumi, Komatsu, Hisateru, Hirota, Masashi, Miyazaki, Yasuhiro, Tomokuni, Akira, Motoori, Masaaki, Iwase, Kazuhiro, Fujitani, Kazumasa

“…The patient is a 70s woman. She underwent cystectomy for bladder cancer 6 years ago and had a ureterocutaneous fistula in the right lower abdomen. After…”
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Phase II/III Results of a Trial of Anti–Tumor Necrosis Factor Multivalent NANOBODY Compound Ozoralizumab in Patients With Rheumatoid Arthritis by Takeuchi, Tsutomu, Kawanishi, Masafumi, Nakanishi, Megumi, Yamasaki, Hironori, Tanaka, Yoshiya

“…Objective To assess the efficacy and safety of subcutaneous administration of 30 mg or 80 mg of ozoralizumab plus methotrexate (MTX) in patients with…”
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Inhibition of Self-Renewal and Induction of Neural Differentiation by PACAP in Neural Progenitor Cells by HIROSE, MEGUMI, HASHIMOTO, HITOSHI, IGA, JUNKO, SHINTANI, NORIHITO, NAKANISHI, MEGUMI, ARAKAWA, NAOHISA, SHIMADA, TAKESHI, BABA, AKEMICHI

“…:  Several lines of evidence have suggested roles for pituitary adenylate cyclase‐activating polypeptide (PACAP) in the developing nervous system. Previously,…”
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Efficacy and safety of the anti-TNF multivalent NANOBODY® compound ozoralizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: A 52-week result of a Phase II/III study (OHZORA trial) by Tanaka, Yoshiya, Kawanishi, Masafumi, Nakanishi, Megumi, Yamasaki, Hironori, Takeuchi, Tsutomu

“…ABSTRACT Objective To assess the efficacy and safety through a 52-week treatment with subcutaneous ozoralizumab at 30 or 80 mg in patients with active…”
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Efficacy and safety of anti-TNF multivalent NANOBODY® compound ‘ozoralizumab’ without methotrexate co-administration in patients with active rheumatoid arthritis: A 52-week result of phase III, randomised, open-label trial (NATSUZORA trial) by Tanaka, Yoshiya, Kawanishi, Masafumi, Nakanishi, Megumi, Yamasaki, Hironori, Takeuchi, Tsutomu

“…ABSTRACT Objectives The aim is to assess the efficacy and safety of a 52-week subcutaneous ozoralizumab treatment at 30 and 80 mg without methotrexate (MTX) in…”
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Effect of the extended dosing interval of anti-TNF-α NANOBODY® compound ozoralizumab in patients with low disease activity rheumatoid arthritis by Takeuchi, Tsutomu, Nakanishi, Megumi, Kawanishi, Masafumi, Yamasaki, Hironori, Tanaka, Yoshiya

“…This article aims to evaluate the effect of the extended dosing interval on the efficacy and safety of ozoralizumab in patients with rheumatoid arthritis (RA)…”
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Oligoclonal IgG bands revealed to be constituted with NMDAR autoantibodies in a patient with anti-NMDA receptor encephalitis by Fujita-Nakata, Michiyo, Minato, Naomi, Nakanishi, Megumi, Nagayama, Shigemi, Asahina, Masato, Tanaka, Keiko

“…•Oligoclonal IgG bands (OCBs) in cerebrospinal fluid (CSF) are markers of central nervous system (CNS) inflammation, though their specific components remain…”
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Moyamoya Disease Presenting with an Acute Confusional State in an Elderly Patient by Nakanishi, Megumi, MD, PhD, Kaito, Muichi, MD, Gondo, Yuichiro, MD, Takada, Hisashi, MD, PhD, Matsui, Makoto, MD, PhD, Hirose, Genjiro, MD, PhD

“…Moyamoya disease is the angiographic diagnosis of a clinical syndrome showing bilateral stenosis or occlusion of the distal internal carotid arteries and their…”
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Induction of humoral responses specific for paraneoplastic cerebellar degeneration-associated antigen by whole recombinant yeast immunization by Saiki, Misuzu, Sakai, Koichiro, Saiki, Shinji, Kitagawa, Yoko, Nakanishi, Megumi, Hirose, Genjiro

“…Paraneoplastic cerebellar degeneration (PCD) is a potent autoimmune disorder in which antigen-driven responses toward the onconeural antigen are assumed to…”
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Differential expression of mRNAs for PACAP and its receptors during neural differentiation of embryonic stem cells by Hirose, Megumi, Hashimoto, Hitoshi, Shintani, Norihito, Nakanishi, Megumi, Arakawa, Naohisa, Iga, Junko, Niwa, Hitoshi, Miyazaki, Jun-ichi, Baba, Akemichi

“…The expressions of mRNAs for pituitary adenylate cyclase-activating polypeptide (PACAP), vasoactive intestinal peptide (VIP), and their receptors (PAC 1, VPAC…”
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2D-01 8-Oxoguanine increases the frequency of meiotic homologus recombination via DNA strand breaks in mouse tissues by OHNO Mizuki, SAKUMI Kunihiko, FURUICHI Masato, NAKANISHI Megumi, TSUZUKI Teruhisa, NAKABEPPU Yusaku

“…To evaluate the contribution of 8-oxoguanine (8-oxoG) in meiotic homologous recombination, we compared the frequency of meiotic recombination in spermatocytes…”
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