Search Results - "NAKANE, Takahisa"
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Ecological and pharmacognostical characteristics in Ephedra saxatilis in the Yarlung Zangbo River Valley of southeastern Tibetan Plateau, China
Published in Journal of natural medicines (01-06-2023)“…In the Yarlung Zangbo River Valley of the southeastern Tibetan Plateau, China (29°07′49.5"N, 92°41′11.0"E, 3256 m above sea level), we found an Ephedra…”
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Impallidane skeleton as a novel triterpenoid methyl ether from rhizomes of Imperata cylindrica var. koenigii f. pallida
Published in Journal of natural medicines (01-03-2023)“…Abstruct n -Hexane extract of rhizomes of Imperata cylindrica var. koenigii f. pallida yielded five novel skeletal triterpenoids, designed as impallidin ( 1 ),…”
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Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein degrader
Published in Journal of biochemistry (Tokyo) (01-06-2022)“…Abstract Dysregulated yes-associated protein (YAP) is involved in several malignant cancers. However, discovering a druggable YAP inhibitor(s) is difficult…”
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Flavonoids from Sedum japonicum subsp. oryzifolium (Crassulaceae)
Published in Molecules (Basel, Switzerland) (07-11-2022)“…Twenty-two flavonoids were isolated from the leaves and stems of Sedum japonicum subsp. oryzifolium (Crassulaceae). Of these compounds, five flavonoids were…”
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Environmental and soil characteristics in Ephedra habitats of Uzbekistan
Published in Journal of natural medicines (2021)“…In Uzbekistan, Ephedra distachya L., E. equisetina Bunge, E. foliata Boiss. ex C. A. Mey., E. lomatolepis Schrenk, and E. strobilacea Bunge show species…”
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Relationship between ephedrine alkaloid profile in Ephedra gerardiana and soil characteristics of glacial landforms in southeastern Tibetan Plateau, China
Published in Journal of natural medicines (01-06-2022)“…In the Kaluxung River catchment of the southeastern Tibetan Plateau in China, we identified three Ephedra gerardiana communities on different soils and glacial…”
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Quality Testing of Tacrolimus Ointment Mixed with Various Type of Ointments or Creams
Published in Biological & pharmaceutical bulletin (01-11-2018)“…Tacrolimus ointment is used worldwide to treat atopic dermatitis. Although tacrolimus ointment is not suitable for clinical admixtures, it is often mixed with…”
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Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes
Published in Biochemical pharmacology (15-06-2007)“…Involvement of cytochrome P450 (P450 or CYP) 2C19, 2C9, and 3A4 in N-oxidation of voriconazole, a new triazole antifungal agent, has been demonstrated using…”
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Flavonoids and Phenolic Compounds From the Parasitic Gymnosperm Parasitaxus usta Endemic to New Caledonia
Published in Natural product communications (01-01-2022)“…Parasitaxus usta (Podocarpaceae) is the only parasitic gymnosperm and endemic to New Caledonia. In this survey, 11 flavonoids and 6 phenolic compounds were…”
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Three novel 14-epiarborane triterpenoids from Imperata cylindrica Beauv. var. major
Published in Phytochemistry letters (01-08-2018)“…[Display omitted] •Three novel triterpenoids were isolated from the rhizomes of Imperata cylindrica.•Their structures were determined using spectroscopic…”
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Dopamine modulation of chemotactic behavior in response to natural aroma substances in Drosophila melanogaster larvae
Published in Phytomedicine Plus : International journal of phytotherapy and phytopharmacology (01-02-2021)“…•We tested 37 types of essential oils on larval chemotactic behavior.•We identified attractive and aversive aromas of essential oils for larvae.•Dopamine…”
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Physical and chemical characteristics of soils in Ephedra gerardiana and E. pachyclada habitats of Kali Gandaki Valley in Central Nepal
Published in Journal of natural medicines (01-09-2020)“…In the Kali Gandaki Valley in Central Nepal, Ephedra gerardiana and E. pachyclada show species specificity for physical and chemical characteristics of soils…”
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Leishmanicidal Active Withanolides from a Pakistani Medicinal Plant, Withania coagulans
Published in Chemical & pharmaceutical bulletin (2012)“…In the course of screening for leishmanicidal constituents from Asian and South American medicinal plants, a Pakistani medicinal plant, Withania coagulans,…”
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Impallidane skeleton as a novel triterpenoid methyl ether from rhizomes of Imperata cylindrica var. koenigii f. pallida
Published in Journal of natural medicines (01-03-2023)Get full text
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A New Bis-seco-abietane Diterpenoid from Hyptis crenata Pohl ex Benth
Published in Organic letters (05-12-2014)“…A new, highly oxidized, bis-seco-abietane diterpenoid named hyptisolide A (1) was isolated from Hyptis crenata Pohl ex Benth. Its structure and stereochemistry…”
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Water-soluble undenatured type II collagen ameliorates collagen-induced arthritis in mice
Published in Journal of medicinal food (01-11-2013)“…Earlier studies have reported the efficacy of type II collagen (C II) in treating rheumatoid arthritis (RA). However, a few studies have investigated the…”
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Narciclasine is a novel YAP inhibitor that disturbs interaction between YAP and TEAD4
Published in BBA advances (01-01-2021)“…•Narciclasine binds to the N-terminal part of YAP•Narciclasine competes with TEAD4 for binding to YAP•Narciclasine suppresses mesothelioma cell…”
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Triterpene Glycosides from the Roots of Codonopsis lanceolata
Published in Chemical & Pharmaceutical Bulletin (01-03-2008)“…In the course of the development of new designer foods using the roots of Codonopsis lanceolata, we found that hot-water extracts of C. lanceolata recovered…”
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Polyprenylated Benzoylphloroglucinol-Type Derivatives Including Novel Cage Compounds from Hypericum erectum
Published in Chemical & pharmaceutical bulletin (01-03-2010)“…Hyperici erecti herba (Hypericum erectum THUNB.) showed a suppressive effect on generation of isovaleric acid by Corynebacterium xerosis. An ethyl acetate…”
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