Search Results - "NAKAMURA, Yusuke"

Dual Complex of Log Fano Pairs and Its Application to Witt Vector Cohomology by Nakamura, Yusuke

“…Abstract We prove the contractibility of the dual complexes of weak log Fano pairs. As applications, we obtain a vanishing theorem of Witt vector cohomology of…”
Get full text

Critical roles of non-histone protein lysine methylation in human tumorigenesis by Hamamoto, Ryuji, Saloura, Vassiliki, Nakamura, Yusuke

“…Key Points Lysine methylation is widely recognized as a fundamental post-translational modification. Most protein lysine methyltransferases (PKMTs) contain the…”
Get full text

SARS-CoV-2 genomic variations associated with mortality rate of COVID-19 by Toyoshima, Yujiro, Nemoto, Kensaku, Matsumoto, Saki, Nakamura, Yusuke, Kiyotani, Kazuma

“…The coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, has rapidly expanded to a global pandemic. However, numbers of infected cases, deaths,…”
Get full text

Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy by Deng, Xiaolan, Nakamura, Yusuke

“…With the accelerating progress in basic and clinical cancer research, a huge body of new discoveries and powerful technologies has allowed us to implement a…”
Get full text

Overview of the BioBank Japan Project: Study design and profile by Nagai, Akiko, Hirata, Makoto, Kamatani, Yoichiro, Muto, Kaori, Matsuda, Koichi, Kiyohara, Yutaka, Ninomiya, Toshiharu, Tamakoshi, Akiko, Yamagata, Zentaro, Mushiroda, Taisei, Murakami, Yoshinori, Yuji, Koichiro, Furukawa, Yoichi, Zembutsu, Hitoshi, Tanaka, Toshihiro, Ohnishi, Yozo, Nakamura, Yusuke, Shiono, Masaki, Misumi, Kazuo, Kaieda, Reiji, Harada, Hiromasa, Minami, Shiro, Emi, Mitsuru, Emoto, Naoya, Daida, Hiroyuki, Miyauchi, Katsumi, Murakami, Akira, Asai, Satoshi, Moriyama, Mitsuhiko, Takahashi, Yasuo, Fujioka, Tomoaki, Obara, Wataru, Mori, Seijiro, Ito, Hideki, Nagayama, Satoshi, Miki, Yoshio, Masumoto, Akihide, Yamada, Akira, Nishizawa, Yasuko, Kodama, Ken, Kutsumi, Hiromu, Sugimoto, Yoshihisa, Koretsune, Yukihiro, Kusuoka, Hideo, Yanai, Hideki, Kubo, Michiaki

“…The BioBank Japan (BBJ) Project was launched in 2003 with the aim of providing evidence for the implementation of personalized medicine by constructing a…”
Get full text

Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy by Hamamoto, Ryuji, Nakamura, Yusuke

“…Protein methylation is one of the important post‐translational modifications. Although its biological and physiological functions were unknown for a long time,…”
Get full text

Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2 by Kiyotani, Kazuma, Toyoshima, Yujiro, Nemoto, Kensaku, Nakamura, Yusuke

“…To control and prevent the current COVID-19 pandemic, the development of novel vaccines is an emergent issue. In addition, we need to develop tools that can…”
Get full text

A cross-population atlas of genetic associations for 220 human phenotypes by Sakaue, Saori, Kanai, Masahiro, Tanigawa, Yosuke, Karjalainen, Juha, Kurki, Mitja, Koshiba, Seizo, Narita, Akira, Konuma, Takahiro, Yamamoto, Kenichi, Akiyama, Masato, Ishigaki, Kazuyoshi, Suzuki, Akari, Suzuki, Ken, Obara, Wataru, Yamaji, Ken, Takahashi, Kazuhisa, Asai, Satoshi, Takahashi, Yasuo, Suzuki, Takao, Shinozaki, Nobuaki, Yamaguchi, Hiroki, Minami, Shiro, Murayama, Shigeo, Yoshimori, Kozo, Nagayama, Satoshi, Obata, Daisuke, Higashiyama, Masahiko, Masumoto, Akihide, Koretsune, Yukihiro, Ito, Kaoru, Terao, Chikashi, Yamauchi, Toshimasa, Komuro, Issei, Kadowaki, Takashi, Tamiya, Gen, Yamamoto, Masayuki, Nakamura, Yusuke, Kubo, Michiaki, Murakami, Yoshinori, Yamamoto, Kazuhiko, Kamatani, Yoichiro, Palotie, Aarno, Rivas, Manuel A., Daly, Mark J., Matsuda, Koichi, Okada, Yukinori

“…Current genome-wide association studies do not yet capture sufficient diversity in populations and scope of phenotypes. To expand an atlas of genetic…”
Get full text

Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens by Kiyotani, Kazuma, Chan, Hiu Ting, Nakamura, Yusuke

“…Utilizing the host immune system to eradicate cancer cells has been the most investigated subject in the cancer research field in recent years. However, most…”
Get full text

Breast cancer: The translation of big genomic data to cancer precision medicine by Low, Siew‐Kee, Zembutsu, Hitoshi, Nakamura, Yusuke

“…Cancer is a complex genetic disease that develops from the accumulation of genomic alterations in which germline variations predispose individuals to cancer…”
Get full text

Clonal Hematopoiesis in Liquid Biopsy: From Biological Noise to Valuable Clinical Implications by Chan, Hiu Ting, Chin, Yoon Ming, Nakamura, Yusuke, Low, Siew-Kee

“…The use of blood liquid biopsy is being gradually incorporated into the clinical setting of cancer management. The minimally invasive nature of the usage of…”
Get full text

Myasthenic crisis and polymyositis induced by one dose of nivolumab by Kimura, Toshihiro, Fukushima, Satoshi, Miyashita, Azusa, Aoi, Jun, Jinnin, Masatoshi, Kosaka, Takayuki, Ando, Yukio, Matsukawa, Masakazu, Inoue, Hiroyuki, Kiyotani, Kazuma, Park, Jae‐Hyun, Nakamura, Yusuke, Ihn, Hironobu

“…An 80‐year‐old man, who developed multiple lymph node and skin metastasis of malignant melanoma, received nivolumab monotherapy. Two weeks after the first…”
Get full text

Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies by Choudhury, Noura, Nakamura, Yusuke

“…In the last 5 years, immune checkpoint antibodies have become established as anticancer agents for various types of cancer. These antibody drugs, namely…”
Get full text

Personalized immunotherapy in cancer precision medicine by Kiyotani, Kazuma, Toyoshima, Yujiro, Nakamura, Yusuke

“…With the significant advances in cancer genomics using next-generation sequencing technologies, genomic and molecular profiling-based precision medicine is…”
Get full text

Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy? by Pittella-Silva, Fabio, Chin, Yoon Ming, Chan, Hiu Ting, Nagayama, Satoshi, Miyauchi, Eisaku, Low, Siew-Kee, Nakamura, Yusuke

“…Abstract Background Blood-based analysis of circulating tumor DNA (ctDNA) is a promising tool for cancer screening, monitoring relapse/recurrence and…”
Get full text

Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors by Kiyotani, Kazuma, Mai, Tu H, Nakamura, Yusuke

“…Accurate human leukocyte antigen (HLA) genotyping is critical in studies involving the immune system. Several algorithms to estimate HLA genotypes from…”
Get full text

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism by Ariyoshi, Mariko, Shirakawa, Masahiro, Arita, Kyohei, Tochio, Hidehito, Nakamura, Yusuke

“…DNA methylation of CpG dinucleotides is an important epigenetic modification of mammalian genomes and is essential for the regulation of chromatin structure,…”
Get full text

Genetic variations in medical research in the past, at present and in the future by KAMATANI, Yoichiro, NAKAMURA, Yusuke

“…As we look so different, our genomic sequences vary enormously. The differences in our genome, genetic variations, have played very significant roles in…”
Get full text

Three-Dimensional Evaluation of Internal Structure of Coke Made by Blending Non-coking Coal Using X-ray Computed Tomography by Matsukawa, Yoshiya, Nakamura, Yusuke, Igawa, Daisuke, Matsui, Takashi, Aoki, Hideyuki

“…Image analysis was performed on the analytical objects constructed by X-ray computed tomography images of coke with anthracite as low swelling and…”
Get full text

Genome-wide association study of hematological and biochemical traits in a Japanese population by Nakamura, Yusuke, Matsuda, Koichi, Daigo, Yataro, Kamatani, Yoichiro, Okada, Yukinori, Kamatani, Naoyuki, Kubo, Michiaki, Hosono, Naoya

“…Naoyuki Kamatani and colleagues report genome-wide association studies for 8 hematological traits and 12 biochemical traits in a Japanese population. We report…”
Get full text