Search Results - "NAKAMURA, MASAYA"

Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells by Nakamura, Masaya, Okano, Hideyuki

“…Stimulated by the 2012 Nobel Prize in Physiology or Medicine awarded for Shinya Yamanaka and Sir John Gurdon, there is an increasing interest in the induced…”
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Steps Toward Safe Cell Therapy Using Induced Pluripotent Stem Cells by Okano, Hideyuki, Nakamura, Masaya, Yoshida, Kenji, Okada, Yohei, Tsuji, Osahiko, Nori, Satoshi, Ikeda, Eiji, Yamanaka, Shinya, Miura, Kyoko

“…The enthusiasm for producing patient-specific human embryonic stem cells using somatic nuclear transfer has somewhat abated in recent years because of ethical,…”
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Automatic measurement of the Cobb angle for adolescent idiopathic scoliosis using convolutional neural network by Maeda, Yoshihiro, Nagura, Takeo, Nakamura, Masaya, Watanabe, Kota

“…This study proposes a convolutional neural network method for automatic vertebrae detection and Cobb angle (CA) measurement on X-ray images for scoliosis. 1021…”
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Cell therapy for spinal cord injury using induced pluripotent stem cells by Nagoshi, Narihito, Tsuji, Osahiko, Nakamura, Masaya, Okano, Hideyuki

“…For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology,…”
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The 5-Item Modified Frailty Index Is Predictive of Severe Adverse Events in Patients Undergoing Surgery for Adult Spinal Deformity by Yagi, Mitsuru, Michikawa, Takehiro, Hosogane, Naobumi, Fujita, Nobuyuki, Okada, Eijiro, Suzuki, Satoshi, Tsuji, Osahiko, Nagoshi, Narihito, Asazuma, Takashi, Tsuji, Takashi, Nakamura, Masaya, Matsumoto, Morio, Watanabe, Kota

“…STUDY DESIGN.A retrospective review of 281 consecutive cases of adult spine deformity (ASD) surgery (age 55 ± 19 yrs, 91% female, follow-up 4.3 ± 1.9 yrs) from…”
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High-level production of 2-pyrone-4,6-dicarboxylic acid from vanillic acid as a lignin-related aromatic compound by metabolically engineered fermentation to realize industrial valorization processes of lignin by Otsuka, Yuichiro, Araki, Takuma, Suzuki, Yuzo, Nakamura, Masaya, Kamimura, Naofumi, Masai, Eiji

“…[Display omitted] •Improvement of the production efficiency of PDC from vanillic acid was investigated.•The maintenance of primary metabolic activity is…”
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Comparison of three artificial intelligence algorithms for automatic cobb angle measurement using teaching data specific to three disease groups by Kato, Shuzo, Maeda, Yoshihiro, Nagura, Takeo, Nakamura, Masaya, Watanabe, Kota

“…Spinal deformities, including adolescent idiopathic scoliosis (AIS) and adult spinal deformity (ASD), affect many patients. The measurement of the Cobb angle…”
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Prevalence and characteristics of chronic musculoskeletal pain in Japan by Nakamura, Masaya, Toyama, Yoshiaki, Nishiwaki, Yuji, Ushida, Takahiro

“…This cross-sectional study was conducted to obtain epidemiologic data on chronic musculoskeletal pain in the Japanese people, and with it a better…”
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Impact of Frailty and Comorbidities on Surgical Outcomes and Complications in Adult Spinal Disorders by Yagi, Mitsuru, Fujita, Nobuyuki, Okada, Eijiro, Tsuji, Osahiko, Nagoshi, Narihito, Tsuji, Takashi, Asazuma, Takashi, Nakamura, Masaya, Matsumoto, Morio, Watanabe, Kota

“…STUDY DESIGN.Retrospective review of surgically treated 481 adult patients with spinal disorders OBJECTIVE.To elucidate the effect of frailty and comorbidities…”
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Concise Review: Laying the Groundwork for a First‐In‐Human Study of an Induced Pluripotent Stem Cell‐Based Intervention for Spinal Cord Injury by Tsuji, Osahiko, Sugai, Keiko, Yamaguchi, Ryo, Tashiro, Syoichi, Nagoshi, Narihito, Kohyama, Jun, Iida, Tsuyoshi, Ohkubo, Toshiki, Itakura, Go, Isoda, Miho, Shinozaki, Munehisa, Fujiyoshi, Kanehiro, Kanemura, Yonehiro, Yamanaka, Shinya, Nakamura, Masaya, Okano, Hideyuki

“…There have been numerous attempts to develop stem cell transplantation approaches to promote the regeneration of spinal cord injury (SCI). Our multicenter team…”
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Mechanisms of Stem Cell Therapy in Spinal Cord Injuries by Shinozaki, Munehisa, Nagoshi, Narihito, Nakamura, Masaya, Okano, Hideyuki

“…Every year, 0.93 million people worldwide suffer from spinal cord injury (SCI) with irretrievable sequelae. Rehabilitation, currently the only available…”
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Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice by Nori, Satoshi, Okada, Yohei, Yasuda, Akimasa, Tsuji, Osahiko, Takahashi, Yuichiro, Kobayashi, Yoshiomi, Fujiyoshi, Kanehiro, Koike, Masato, Uchiyama, Yasuo, Ikeda, Eiji, Toyama, Yoshiaki, Yamanaka, Shinya, Nakamura, Masaya, Okano, Hideyuki

“…Once their safety is confirmed, human-induced pluripotent stem cells (hiPSCs), which do not entail ethical concerns, may become a preferred cell source for…”
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Reliability of Trapezius Muscle Hardness Measurement: A Comparison between Portable Muscle Hardness Meter and Ultrasound Strain Elastography by Sawada, Tomonori, Okawara, Hiroki, Nakashima, Daisuke, Iwabuchi, Shuhei, Matsumoto, Morio, Nakamura, Masaya, Nagura, Takeo

“…Prolonged computer work and smartphone use can cause stiffness of the neck and shoulder muscles, including the trapezius muscle. Hence, muscle hardness…”
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Regenerative therapy for spinal cord injury using iPSC technology by Nagoshi, Narihito, Okano, Hideyuki, Nakamura, Masaya

“…Spinal cord injury (SCI) is a devastating event that causes permanent neurologic impairments. Cell transplantation therapy using neural precursor cells (NPCs)…”
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A study on the use of the Osstell apparatus to evaluate pedicle screw stability: An in-vitro study using micro-CT by Nakashima, Daisuke, Ishii, Ken, Matsumoto, Morio, Nakamura, Masaya, Nagura, Takeo

“…Pull-out force and insertion torque have not been generally used as intraoperative measures for the evaluation of pedicle screw stability because of their…”
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First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol by Sugai, Keiko, Sumida, Miho, Shofuda, Tomoko, Yamaguchi, Ryo, Tamura, Takashi, Kohzuki, Tsuneo, Abe, Takayuki, Shibata, Reo, Kamata, Yasuhiro, Ito, Shuhei, Okubo, Toshiki, Tsuji, Osahiko, Nori, Satoshi, Nagoshi, Narihito, Yamanaka, Shinya, Kawamata, Shin, Kanemura, Yonehiro, Nakamura, Masaya, Okano, Hideyuki

“…Our group has conducted extensive basic and preclinical studies of the use of human induced pluripotent cell (iPSC)-derived neural stem/progenitor cell…”
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Plasticity and regeneration in the injured spinal cord after cell transplantation therapy by Nori, Satoshi, Nakamura, Masaya, Okano, Hideyuki

“…Spinal cord injury (SCI) typically damages the long axonal tracts of the spinal cord which results in permanent disability. However, regeneration of the…”
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Laser resonance frequency analysis of pedicle screw stability: A cadaveric model bone study by Nakashima, Daisuke, Mikami, Katsuhiro, Kikuchi, Shunsuke, Nishikino, Masaharu, Kitamura, Toshiyuki, Hasegawa, Noboru, Matsumoto, Morio, Nakamura, Masaya, Nagura, Takeo

“…There is no evaluation method currently available to assess intraoperative pedicle screw fixation (PSF) strength. In this study, we established a laser‐based…”
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Treadmill training based on the overload principle promotes locomotor recovery in a mouse model of chronic spinal cord injury by Shibata, Takahiro, Tashiro, Syoichi, Shinozaki, Munehisa, Hashimoto, Shogo, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki, Nagoshi, Narihito

“…Rehabilitative treatment, including treadmill training, is considered an important strategy for restoring motor function after spinal cord injury (SCI)…”
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Enhancement of protocatechuate decarboxylase activity for the effective production of muconate from lignin-related aromatic compounds by Sonoki, Tomonori, Morooka, Miyuki, Sakamoto, Kimitoshi, Otsuka, Yuichiro, Nakamura, Masaya, Jellison, Jody, Goodell, Barry

“…•Protocatechuate decarboxylation is a rate-limiting step in muconate production.•We identified a way to enhance protocatechuate decarboxylase…”
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