Search Results - "NAKAJIMA, Yoshitsugu"

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  1. 1

    MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS by NAKAJIMA, Yoshitsugu, MIZOBUCHI, Minoru, NAKAMURA, Masahiro, TAKAGI, Hidetoshi, INAGAKI, Haruhisa, KOMINAMI, Goro, KOIKE, Masahiro, YAMAGUCHI, Toshiro

    Published in Drug metabolism and disposition (01-12-2004)
    “…The Ministry of Health and Welfare, Japan banned coadministration of carbapenems, such as panipenem/betamipron (PAPM), meropenem (MEPM), and valproic acid…”
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  2. 2

    DISTRIBUTION AND EXCRETION OF BORON AFTER INTRAVENOUS ADMINISTRATION OF DISODIUM MERCAPTOUNDECAHYDRO-CLOSO-DODECABORATE TO RATS by YAMAGUCHI, Toshiro, NAKAJIMA, Yoshitsugu, MIYAMOTO, Hiroyuki, MIZOBUCHI, Minoru, KANAZU, Takushi, KADONO, Kyoko, NAKAMOTO, Kayo, IKEUCHI, Isao

    Published in Journal of toxicological sciences (1998)
    “…Disodium mercaptoundecahydro-closo-dodecaborate (BSH) is an important compound for boron neutron capture therapy. The pharmacokinetics of boron by BSH were…”
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  3. 3

    Possible mechanism for species difference on the toxicity of pivalic acid between dogs and rats by Yamaguchi, Toshiro, Nakajima, Yoshitsugu, Nakamura, Yutaka

    Published in Toxicology and applied pharmacology (01-07-2006)
    “…In a high dose toxicity study of pivalic acid (PA), PA caused skeletal muscle disorder in dog, and a significant increase of pivaloyl carnitine (PC) was…”
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  4. 4

    Isolation of Perisoxal Glucuronides and Determination of Enantiomeric Ratios of d-and l-Perisoxal Metabolites excreted in Rabbit Urine by MIZOJIRI, KENJI, YAMAMOTO, ETSUKO, NAKAJIMA, YOSHITSUGU, OKABE, HIROSHI, SUGENO, KOICHI, WATANABE, JUN

    “…Perisoxal glucuronides were isolated from rabbit urine after repeated subcutaneous administration of dl-perisoxal citrate. Optical rotatory analysis of free…”
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  5. 5

    Determination of Perisoxal and Its Phenolic Metabolites in Rat, Rabbit and Human Urine by MIZOJIRI, KENJI, YAMAMOTO, ETSUKO, NAKAJIMA, YOSHITSUGU, OKABE, HIROSHI, SUGENO, KOICHI, WATANABE, JUN

    Published in Chemical & pharmaceutical bulletin (01-01-1980)
    “…After a single administration of perisoxal citrate to rats (21 mg/kg, i. v.), rabbits (15 mg/kg, i. v.) and humans (200 mg/man, p. o.), urinary excretion of…”
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  6. 6

    Absorption, Excretion, Distribution and Metabolism of Perisoxal in Rats by WATANABE, JUN, OKABE, HIROSHI, MIZOJIRI, KENJI, NAKAJIMA, YOSHITSUGU, SUGENO, KOICHI, YAMAMOTO, RYUICHI

    Published in Chemical & pharmaceutical bulletin (01-01-1979)
    “…The drug was well absorbed from the intestinal tract, and the bulk of it was excreted in the urine and feces. Biliary excretion was significant, and the…”
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  7. 7
  8. 8

    Disposition and metabolism of the new hypocholesterolemic compound S-8921 in rats and dogs by Yamaguchi, T, Nakajima, Y, Mizobuchi, M, Inazawa, K, Kanazu, T, Kadono, K, Ohkawa, T, Iwatani, K

    Published in Arzneimittel-Forschung (01-10-1998)
    “…S-8921 (methyl 1-(3,4-dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimeth oxy-2- naphthoate, CAS 151165-96-7) is a novel hypocholesterolemic agent…”
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