Search Results - "NAKAJIMA, Yoshitsugu"
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MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS
Published in Drug metabolism and disposition (01-12-2004)“…The Ministry of Health and Welfare, Japan banned coadministration of carbapenems, such as panipenem/betamipron (PAPM), meropenem (MEPM), and valproic acid…”
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DISTRIBUTION AND EXCRETION OF BORON AFTER INTRAVENOUS ADMINISTRATION OF DISODIUM MERCAPTOUNDECAHYDRO-CLOSO-DODECABORATE TO RATS
Published in Journal of toxicological sciences (1998)“…Disodium mercaptoundecahydro-closo-dodecaborate (BSH) is an important compound for boron neutron capture therapy. The pharmacokinetics of boron by BSH were…”
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Possible mechanism for species difference on the toxicity of pivalic acid between dogs and rats
Published in Toxicology and applied pharmacology (01-07-2006)“…In a high dose toxicity study of pivalic acid (PA), PA caused skeletal muscle disorder in dog, and a significant increase of pivaloyl carnitine (PC) was…”
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Isolation of Perisoxal Glucuronides and Determination of Enantiomeric Ratios of d-and l-Perisoxal Metabolites excreted in Rabbit Urine
Published in Chemical & pharmaceutical bulletin (1981)“…Perisoxal glucuronides were isolated from rabbit urine after repeated subcutaneous administration of dl-perisoxal citrate. Optical rotatory analysis of free…”
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Determination of Perisoxal and Its Phenolic Metabolites in Rat, Rabbit and Human Urine
Published in Chemical & pharmaceutical bulletin (01-01-1980)“…After a single administration of perisoxal citrate to rats (21 mg/kg, i. v.), rabbits (15 mg/kg, i. v.) and humans (200 mg/man, p. o.), urinary excretion of…”
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Absorption, Excretion, Distribution and Metabolism of Perisoxal in Rats
Published in Chemical & pharmaceutical bulletin (01-01-1979)“…The drug was well absorbed from the intestinal tract, and the bulk of it was excreted in the urine and feces. Biliary excretion was significant, and the…”
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Disposition and metabolism of the new hypocholesterolemic compound S-8921 in rats and dogs
Published in Arzneimittel-Forschung (01-10-1998)“…S-8921 (methyl 1-(3,4-dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimeth oxy-2- naphthoate, CAS 151165-96-7) is a novel hypocholesterolemic agent…”
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