Search Results - "NAKADA, Tsutomu"
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Virchow-Robin space and aquaporin-4: new insights on an old friend
Published in Croatian medical journal (01-08-2014)“…Recent studies have strongly indicated that the classic circulation model of cerebrospinal fluid (CSF) is no longer valid. The production of CSF is not only…”
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Fluid Dynamics Inside the Brain Barrier: Current Concept of Interstitial Flow, Glymphatic Flow, and Cerebrospinal Fluid Circulation in the Brain
Published in The Neuroscientist (01-04-2019)“…The discovery of the water specific channel, aquaporin, and abundant expression of its isoform, aquaporin-4 (AQP-4), on astrocyte endfeet brought about…”
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The Molecular Mechanisms of Neural Flow Coupling: A New Concept
Published in Journal of neuroimaging (01-11-2015)“…ABSTRACT The phenomenon known as neural flow coupling (NFC) occurs at the capillary level where there are no known pressure controlling structures. Recent…”
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Physical interaction of junctophilin and the CaV1.1 C terminus is crucial for skeletal muscle contraction
Published in Proceedings of the National Academy of Sciences - PNAS (24-04-2018)“…Close physical association of CaV1.1 L-type calcium channels (LTCCs) at the sarcolemmal junctional membrane (JM) with ryanodine receptors (RyRs) of the…”
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Aquaporin-4 Functionality and Virchow-Robin Space Water Dynamics: Physiological Model for Neurovascular Coupling and Glymphatic Flow
Published in International journal of molecular sciences (18-08-2017)“…The unique properties of brain capillary endothelium, critical in maintaining the blood-brain barrier (BBB) and restricting water permeability across the BBB,…”
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Clinical application of high and ultra high-field MRI
Published in Brain & development (Tokyo. 1979) (01-07-2007)“…The 21st century ushered in the century of human beings. The previous era characterized by the chase after super technology has been replaced by a new era…”
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Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke
Published in Brain (London, England : 1878) (01-07-2015)“…In the central nervous system, progranulin, a glycoprotein growth factor, plays a crucial role in maintaining physiological functions, and progranulin gene…”
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Automaticity of pitch class-color synesthesia as revealed by a Stroop-like effect
Published in Consciousness and cognition (01-05-2019)“…•Pitch classes evoke color sensations in pitch class-color synesthesia.•We observed a Stroop-like effect between pitch class and color.•Thus, the color…”
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Rh glycoprotein expression is modulated in pufferfish (Takifugu rubripes) during high environmental ammonia exposure
Published in Journal of experimental biology (15-09-2010)“…Rhesus (Rh) protein involvement in ammonia transport processes in freshwater fish has received considerable attention; however, parallel investigations in…”
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Increase in phospholamban content in mouse skeletal muscle after denervation
Published in Journal of muscle research and cell motility (01-12-2018)“…It is well-known that denervation of motor nerves induces atrophy and decreases contractile force of the skeletal muscle. However, it is not completely…”
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Musical pitch classes have rainbow hues in pitch class-color synesthesia
Published in Scientific reports (19-12-2017)“…Synesthesia, an anomalous blending of senses in which stimulation of one sensory modality produces sensation in a different modality, provides a unique…”
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Developmental abnormalities of the brain exposed to childhood maltreatment detected by diffusion tensor imaging
Published in Neurological research (New York) (02-01-2019)“…Objective: This study aimed to investigate brain developmental alterations in individuals exposed to childhood maltreatment (CM) with dissociative experiences…”
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A reconstituted depolarization-induced Ca2+ release platform for validation of skeletal muscle disease mutations and drug discovery
Published in The Journal of general physiology (05-12-2022)“…In skeletal muscle excitation-contraction (E-C) coupling, depolarization of the plasma membrane triggers Ca2+ release from the sarcoplasmic reticulum (SR),…”
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14
Abnormal distribution of GABAA receptors in brain of duchenne muscular dystrophy patients
Published in Muscle & nerve (01-04-2017)“…ABSTRACT Introduction: In this study we sought to: (1) determine the distribution of GABAA receptors (GABAA‐Rs) in the brain of Duchenne muscular dystrophy…”
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Identification of intestinal bicarbonate transporters involved in formation of carbonate precipitates to stimulate water absorption in marine teleost fish
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-04-2008)“…Marine teleost fish precipitate divalent cations as carbonate deposits in the intestine to minimize the potential for excessive Ca2+ entry and to stimulate…”
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Expression and Clinical Significance of Spi-B in B-cell Acute Lymphoblastic Leukemia
Published in The journal of histochemistry and cytochemistry (01-10-2022)“…Spi-B, a member of the E26 transformation-specific (ETS) family of transcription factors, plays an important role in B cell differentiation. Spi-B also…”
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Ammonia secretion from fish gill depends on a set of Rh glycoproteins
Published in The FASEB journal (01-04-2007)“…ABSTRACT Ammonia excretion from the gill in teleost fish is essential for nitrogen elimination. Although numerous physiological studies have measured ammonia…”
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Identification of Aquaporin 4 inhibitors using in vitro and in silico methods
Published in Bioorganic & medicinal chemistry (2009)“…Eighteen compounds were studied for Aquaporin 4 inhibition using in vitro and in silico methods, of which 10 were found to clearly inhibit its water transport…”
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Neural mechanisms underlying the orienting response to subject's own name: An event-related potential study
Published in Psychophysiology (01-06-2012)“…Neural processes underlying the orienting response (OR) to subject's own name (SON) were investigated using the oddball paradigm. Subjects were presented with…”
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Localization of ammonia transporter Rhcg1 in mitochondrion-rich cells of yolk sac, gill, and kidney of zebrafish and its ionic strength-dependent expression
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-10-2007)“…Members of the Rh glycoprotein family have been shown to be involved in ammonia transport in a variety of species. Here we show that zebrafish Rhcg1, a member…”
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