Search Results - "NAIR, Sujit S"

A Core Chromatin Remodeling Factor Instructs Global Chromatin Signaling through Multivalent Reading of Nucleosome Codes by Nair, Sujit S., Li, Da-Qiang, Kumar, Rakesh

“…ATP-dependent NuRD repressor complexes involve combinatorial assembly of its subunits. However, the mechanism of gene transcription by MTA1/NuRD remains…”
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Chromatin remodeling in Cancer: A Gateway to regulate gene Transcription by Nair, Sujit S., Kumar, Rakesh

“…Cancer cells are remarkably adaptive to diverse survival strategies, probably due to its ability to interpret signaling cues differently than the normal cells…”
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Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer by Chakravarty, Dimple, Nair, Sujit S., Hammouda, Nada, Ratnani, Parita, Gharib, Yasmine, Wagaskar, Vinayak, Mohamed, Nihal, Lundon, Dara, Dovey, Zachary, Kyprianou, Natasha, Tewari, Ashutosh K.

“…The recent outbreak of infections and the pandemic caused by SARS-CoV-2 represent one of the most severe threats to human health in more than a century…”
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Metastasis-Associated Protein 1/Nucleosome Remodeling and Histone Deacetylase Complex in Cancer by LI, Da-Qiang, PAKALA, Suresh B, NAIR, Sujit S, ESWARAN, Jeyanthy, KUMAR, Rakesh

“…Cancer cells frequently exhibit deregulation of coregulatory molecules to drive the process of growth and metastasis. One such group of ubiquitously expressed…”
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MORC2 Signaling Integrates Phosphorylation-Dependent, ATPase-Coupled Chromatin Remodeling during the DNA Damage Response by Li, Da-Qiang, Nair, Sujit S., Ohshiro, Kazufumi, Kumar, Anupam, Nair, Vasudha S., Pakala, Suresh B., Reddy, Sirigiri Divijendra Natha, Gajula, Rajendra P., Eswaran, Jeyanthy, Aravind, L., Kumar, Rakesh

“…Chromatin dynamics play a central role in maintaining genome integrity, but how this is achieved remains largely unknown. Here, we report that microrchidia…”
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Leveraging 5G technology for robotic surgery and cancer care by Pandav, Krunal, Te, Austen G., Tomer, Nir, Nair, Sujit S., Tewari, Ashutosh K.

“…Background The field of robotic surgery has seen significant advancements in the past few years and it has been adopted in many large hospitals in the United…”
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Racial disparity in prostate cancer in the African American population with actionable ideas and novel immunotherapies by Dovey, Zachary S., Nair, Sujit S., Chakravarty, Dimple, Tewari, Ashutosh K.

“…Background African Americans (AAs) in the United States are known to have a higher incidence and mortality for Prostate Cancer (PCa). The drivers of this…”
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A transcriptomic signature of tertiary Gleason 5 predicts worse clinicopathological outcome by Martini, Alberto, Wang, Joanna, Brown, Nicholas M., Cumarasamy, Shivaram, Sfakianos, John P., Rastinehad, Ardeshir R., Haines, Kenneth G., Wiklund, Nils Peter, Nair, Sujit S., Tewari, Ashutosh K.

“…Objective To investigate the genomic features of tertiary pattern 5 (TP5) on radical prostatectomy specimens in an effort to explain the poor clinical outcomes…”
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Extranuclear Functions of ER Impact Invasive Migration and Metastasis by Breast Cancer Cells by CHAKRAVARTY, Dimple, NAIR, Sujit S, LEE, Francis Y, RAO TEKMAL, Rajeshwar, KUMAR, Rakesh, VADIAMUDI, Ratna K, SANTHAMMA, Bindu, NAIR, Binoj C, LONG WANG, BANDYOPADHYAY, Abhik, AGYIN, Joseph K, BRANN, Darrell, SUN, Lu-Zhe, YEH, I-Tien

“…The molecular basis of breast cancer progression to metastasis and the role of estrogen receptor (ER) signaling in this process remain poorly understood…”
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Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells by YUN ZHU, SULLIVAN, Lacey L, NAIR, Sujit S, WILLIAMS, Christopher C, PANDEY, Arvind K, MARRERO, Luis, VADLAMUDI, Ratna K, JONES, Frank E

“…Although crosstalk between cell-surface and nuclear receptor signaling pathways has been implicated in the development and progression of endocrine-regulated…”
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The Rapid Coronavirus Antibody Test: Can We Improve Accuracy? by Pavlova, Ina P, Nair, Sujit S, Kyprianou, Natasha, Tewari, Ash K

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Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A by Molli, Poonam R, Li, Da-Qiang, Bagheri-Yarmand, Rozita, Pakala, Suresh B, Katayama, Hiroshi, Sen, Subrata, Iyer, Jyoti, Chernoff, Jonathan, Tsai, Ming-Ying, Nair, Sujit S, Kumar, Rakesh

“…Here we provide evidence in support of an inherent role for Arpc1b, a component of the Arp2/3 complex, in regulation of mitosis and demonstrate that its…”
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Cyclin-Dependent Kinase―Mediated Phosphorylation Plays a Critical Role in the Oncogenic Functions of PELP1 by NAIR, Binoj C, NAIR, Sujit S, CHAKRAVARTY, Dimple, CHALLA, Rambabu, MANAVATHI, Bramanandam, RENEE YEW, P, KUMAR, Rakesh, RAO TEKMAL, Rajeshwar, VADLAMUDI, Ratna K

“…Estrogen receptor (ER) signaling plays an important role in breast cancer progression, and ER functions are influenced by coregulatory proteins. PELP1…”
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Impact of COVID-19 on Prostate Cancer Management: Guidelines for Urologists by Dovey, Zachary, Mohamed, Nihal, Gharib, Yasmine, Ratnani, Parita, Hammouda, Nada, Nair, Sujit S., Chakravarty, Dimple, Sobotka, Stanislaw, Lantz, Anna, Wiklund, Peter, Kyprianou, Natasha, Tewari, Ash

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has resulted in a global health emergency, the like of which has never been seen…”
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Functional implications of altered subcellular localization of PELP1 in breast cancer cells by VADLAMUDI, Ratna K, MANAVATHI, Bramanandam, BALASENTHIL, Seetharaman, NAIR, Sujit S, ZHIBO YANG, SAHIN, Aysegul A, KUMAR, Rakesh

“…It is increasingly accepted that steroidal receptor co-regulators may also function in the cytoplasmic compartment. Proline-, glutamic acid-, and leucine-rich…”
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Regulation of rDNA transcription by proto-oncogene PELP1 by Gonugunta, Vijay K, Nair, Binoj C, Rajhans, Rajib, Sareddy, Gangadhara R, Nair, Sujit S, Vadlamudi, Ratna K

“…Proline-, glutamic acid-, and leucine-rich protein (PELP1) is a novel nuclear receptor coregulator with a multitude of functions. PELP1 serves as a scaffolding…”
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The Tumor Microenvironment and Immunotherapy in Prostate and Bladder Cancer by Nair, Sujit S., Weil, Rachel, Dovey, Zachary, Davis, Avery, Tewari, Ashutosh K.

“…Bladder cancer has been successfully treated with immunotherapy, whereas prostate cancer is a cold tumor with inadequate immune-related treatment response. A…”
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The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer by Chakravarty, Dimple, Sboner, Andrea, Nair, Sujit S., Giannopoulou, Eugenia, Li, Ruohan, Hennig, Sven, Mosquera, Juan Miguel, Pauwels, Jonathan, Park, Kyung, Kossai, Myriam, MacDonald, Theresa Y., Fontugne, Jacqueline, Erho, Nicholas, Vergara, Ismael A., Ghadessi, Mercedeh, Davicioni, Elai, Jenkins, Robert B., Palanisamy, Nallasivam, Chen, Zhengming, Nakagawa, Shinichi, Hirose, Tetsuro, Bander, Neil H., Beltran, Himisha, Fox, Archa H., Elemento, Olivier, Rubin, Mark A.

“…The androgen receptor (AR) plays a central role in establishing an oncogenic cascade that drives prostate cancer progression. Some prostate cancers escape…”
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Potential role of a novel transcriptional coactivator PELP1 in histone H1 displacement in cancer cells by NAIR, Sujit S, MISHRA, Sandip K, ZHIBO YANG, BALASENTHIL, Seetharaman, KUMAR, Rakesh, VADLAMUDI, Ratna K

“…The estrogen receptor plays an important role in breast cancer progression. Proline-, glutamic acid-, and leucine-rich protein 1 (PELP1), also called modulator…”
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Combining alpha radiation-based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor-specific long-term immune response by Domankevich, Vered, Cohen, Adi, Efrati, Margalit, Schmidt, Michael, Rammensee, Hans-Georg, Nair, Sujit S., Tewari, Ashutosh, Kelson, Itzhak, Keisari, Yona

“…Diffusing alpha-emitters radiation therapy (DaRT) is the only known method for treating solid tumors with highly destructive alpha radiation. More importantly,…”
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