Search Results - "NAICKER, Kirsha"

NEPTUNE: Phase 3 Study of First-Line Durvalumab Plus Tremelimumab in Patients With Metastatic NSCLC by de Castro, Jr, Gilberto, Rizvi, Naiyer A, Schmid, Peter, Syrigos, Konstantinos, Martin, Claudio, Yamamoto, Nobuyuki, Cheng, Ying, Moiseyenko, Vladimir, Summers, Yvonne, Vynnychenko, Ihor, Lee, Sung Yong, Bryl, Maciej, Zer, Alona, Erman, Mustafa, Timcheva, Constanta, Raja, Rajiv, Naicker, Kirsha, Scheuring, Urban, Walker, Jill, Mann, Helen, Chand, Vikram, Mok, Tony

“…NEPTUNE, a phase 3, open-label study, evaluated first-line durvalumab plus tremelimumab versus chemotherapy in metastatic NSCLC (mNSCLC). Eligible patients…”
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NEPTUNE China cohort: First-line durvalumab plus tremelimumab in Chinese patients with metastatic non-small-cell lung cancer by Cheng, Ying, Zhou, Qing, Han, Baohui, Fan, Yun, Shan, Li, Chang, Jianhua, Sun, Si, Fang, Jian, Chen, Yuan, Sun, Jianguo, Wu, Gang, Mann, Helen, Naicker, Kirsha, Shire, Norah, Mok, Tony, de Castro, Gilberto

“…•We report prespecified exploratory analyses of an mNSCLC cohort in China (NEPTUNE). 85 chars.•First-line durvalumab + tremelimumab showed a trend of improved…”
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Abstract 5033: The role of the epigenetic regulator SATB2 in colon cancer progression by Brennan, Donal J., Naicker, Kirsha, Das, Sudipto, Moran, Bruce, Klinger, Rut, Ponten, Fredrik, Hewitt, Stephen, Jirström, Karin, Byrne, Annette T., O'Sullivan, Jacintha, Gallagher, William M., O'Connor, Darran P.

“…SATB2 is a nuclear matrix-associated transcription factor that orchestrates gene expression by regulating higher-order chromatin structure. Using…”
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SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas by MAGNUSSON, Kristina, DE WIT, Meike, WESTER, Kenneth, GRY, Marcus, BJARTELL, Anders, GALLAGHER, William M, REXHEPAJ, Elton, KILPINEN, Sami, KALLIONIEMI, Olli-Pekka, BELT, Eric, GOOS, Jeroen, MEIJER, Gerrit, BRENNAN, Donal J, BIRGISSON, Helgi, GLIMELIUS, Bengt, BORREBAECK, Carl A. K, NAVANI, Sanjay, UHLEN, Mathias, O'CONNOR, Darran P, JIRSTRÖM, Karin, PONTEN, Fredrik, JOHNSON, Louis B, MCGEE, Sharon F, LUNDBERG, Emma, NAICKER, Kirsha, KLINGER, Rut, KAMPF, Caroline, ASPLUND, Anna

“…The special AT-rich sequence-binding protein 2 (SATB2), a nuclear matrix-associated transcription factor and epigenetic regulator, was identified as a tissue…”
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Abstract 698: The loss of SATB2 promotes ulcerative colitis-related colon cancer progression through altered localized inflammatory response by Das, Sudipto, Naicker, Kirsha, Klinger, Rut, Fan, Yue, Mallya, Girish, Ponten, Fredrick, Jirström, Karin, O'Sullivan, Jacintha, Gallagher, William M., Brenan, Donal J., O'Connor, Darran P.

“…SATB2 is a member of a family of special AT-rich binding proteins and a novel transcription factor that orchestrates gene expression in a tissue-specific…”
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SATB2 loss and the immune milieu of colorectal cancer (CRC) by O'Connor, Darran, Brennan, Donal J., Naicker, Kirsha, Das, Sudipto, Moran, Bruce, Klinger, Rut, Ponten, Fredrik, Hewitt, Stephen M., Jirstrom, Karin, Byrne, Annette T., O'Sullivan, Jacintha, Gallagher, William M.

“…Abstract only…”
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Abstract LB-444: SATB2 is a novel prognostic factor in colorectal cancer by Naicker, Kirsha, Brennan, Donal, Klinger, Rut, Ponten, Fredrik, Jirstrom, Karin, O'Sullivan, Jacintha, Gallagher, William M., O'Connor, Darran P.

“…SATB2 is a nuclear matrix-associated transcription factor that orchestrates gene expression in a tissue-specific manner by regulating higher order chromatin…”
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