Search Results - "NAGAO, Seigo"

Prolonged mild therapeutic hypothermia versus fever control with tight hemodynamic monitoring and slow rewarming in patients with severe traumatic brain injury: a randomized controlled trial by Maekawa, Tsuyoshi, Yamashita, Susumu, Nagao, Seigo, Hayashi, Nariyuki, Ohashi, Yasuo

“…Although mild therapeutic hypothermia is an effective neuroprotective strategy for cardiac arrest/resuscitated patients, and asphyxic newborns, recent…”
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Edaravone Attenuates Brain Edema and Neurologic Deficits in a Rat Model of Acute Intracerebral Hemorrhage by NAKAMURA, Takehiro, KURODA, Yasuhiro, YAMASHITA, Susumu, XIA ZHANG, MIYAMOTO, Osamu, TAMIYA, Takashi, NAGAO, Seigo, GUOHUA XI, KEEP, Richard F, ITANO, Toshifumi

“…Our previous studies have demonstrated that oxidative DNA injury occurs in the brain after intracerebral hemorrhage (ICH). We therefore examined whether…”
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Guidelines for the Management of Severe Head Injury, 2nd Edition Guidelines from the Guidelines Committee on the Management of Severe Head Injury, the Japan Society of Neurotraumatology by SHIGEMORI, Minoru, ABE, Toshiaki, ARUGA, Tohru, OGAWA, Takeki, OKUDERA, Hiroshi, ONO, Junichi, ONUMA, Takehide, KATAYAMA, Yoichi, KAWAI, Nobuyuki, KAWAMATA, Tatsuro, KOHMURA, Eiji, SAKAKI, Toshisuke, SAKAMOTO, Tetsuya, SASAKI, Tatsuya, SATO, Akira, SHIOGAI, Toshiyuki, SHIMA, Katsuji, SUGIURA, Kazuo, TAKASATO, Yoshio, TOKUTOMI, Takashi, TOMITA, Hiroki, TOYODA, Izumi, NAGAO, Seigo, NAKAMURA, Hiroshi, PARK, Young-soo, MATSUMAE, Mitsunori, MIKI, Tamotsu, MIYAKE, Yasushi, MURAI, Hisayuki, MURAKAMI, Shigeyuki, YAMAURA, Akira, YAMAKI, Tarumi, YAMADA, Kazuo, YOSHIMINE, Toshiki

“…In 1998, the Guidelines Committee on the Management of Severe Head Injury was established by the Japan Society of Neurotraumatology, and performed a critical…”
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Neural stem cells transplantation in cortex in a mouse model of Alzheimer’s disease by Wang, Qinghua, Matsumoto, Yoshihito, Shindo, Tokuhisa, Miyake, Keisuke, Shindo, Atsushi, Kawanishi, Masahiko, Kawai, Nobuyuki, Tamiya, Takashi, Nagao, Seigo

“…Objective. The goal of this study was to elucidate the effect of neurospheres (NS) on dementia in the mouse model of nucleus basalis of Meynert (NBM) lesion…”
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Differences in the neuronal stem cells survival, neuronal differentiation and neurological improvement after transplantation of neural stem cells between mild and severe experimental traumatic brain injury by Shindo, Tokuhisa, Matsumoto, Yoshihito, Wang, Qinghua, Kawai, Nobuyuki, Tamiya, Takashi, Nagao, Seigo

“…We developed a novel protocol for generation and selective amplification of neural progenitor cells regionally specified to the rostral brain but not the…”
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Effects of delayed intraischemic and postischemic hypothermia on a focal model of transient cerebral ischemia in rats by Kawai, N, Okauchi, M, Morisaki, K, Nagao, S

“…Intraischemic mild hypothermia has been shown to be neuroprotective in reducing cerebral infarction in transient focal ischemia. As a more clinical relevant…”
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Evaluation of human fetal neural stem/progenitor cells as a source for cell replacement therapy for neurological disorders: Properties and tumorigenicity after long-term in vitro maintenance by Ogawa, Daisuke, Okada, Yohei, Nakamura, Masaya, Kanemura, Yonehiro, Okano, Hirotaka James, Matsuzaki, Yumi, Shimazaki, Takuya, Ito, Mamoru, Ikeda, Eiji, Tamiya, Takashi, Nagao, Seigo, Okano, Hideyuki

“…It is expected that human neural stem/progenitor cells (hNS/PCs) will some day be used in cell replacement therapies. However, their availability is limited…”
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The present situation of the National University Hospital four years after its set-up as corporation by Nagao, Seigo

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Evaluation of tumor FDG transport and metabolism in primary central nervous system lymphoma using [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) kinetic analysis by Kawai, Nobuyuki, Nishiyama, Yoshihiro, Miyake, Keisuke, Tamiya, Takashi, Nagao, Seigo

“…Although 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) has been used as a promising tool to diagnose primary central nervous system lymphoma…”
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Effect of Delayed Mild Brain Hypothermia on Edema Formation After Intracerebral Hemorrhage in Rats by Kawanishi, Masahiko, MD, Kawai, Nobuyuki, MD, Nakamura, Takehiro, MD, Luo, Chengyi, MD, Tamiya, Takashi, MD, Nagao, Seigo, MD

“…Secondary consequences of intracerebral hemorrhage (ICH) including inflammation, edema, and oxidative damage all contribute to cell death after ICH. Brain…”
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Expression of Matrix Metalloproteinse-9 in Thrombin-Induced Brain Edema Formation in Rats by Kawakita, Kenya, Kawai, Nobuyuki, Kuroda, Yasuhiro, Yasashita, Susumu, Nagao, Seigo

“…Recent evidence has demonstrated that thrombin plays an important role in the development of brain edema by the blood-brain barrier disruption in intracerebral…”
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Matrix metalloproteinase 2 and 9 expression correlated with cavernous sinus invasion of pituitary adenomas by Liu, Weiping, Matsumoto, Yoshihito, Okada, Masaki, Miyake, Keisuke, Kunishio, Katsuzo, Kawai, Nobuyuki, Tamiya, Takashi, Nagao, Seigo

“…Object: Matrix metalloproteinase (MMP) 2 and 9 are important for tissue breakdown in the process of tumor invasion. The aim of this study is to evaluate the…”
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Seizure Suppression in Amygdala-Kindled Mice by Transplantation of Neural Stem/Progenitor Cells Derived From Mouse Embryonic Stem Cells by SHINDO, Atsushi, NAKAMURA, Takehiro, MATSUMOTO, Yoshihito, KAWAI, Nobuyuki, OKANO, Hideyuki, NAGAO, Seigo, ITANO, Toshifumi, TAMIYA, Takashi

“…Embryonic stem cells (ES cells) differentiate into multiple cell lineages including neural cells. The present study optimized the method to induce…”
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FDG-PET findings of the brain in lymphomatoid granulomatosis by Kawai, Nobuyuki, Miyake, Keisuke, Nishiyama, Yoshihiro, Yamamoto, Yuka, Sasakawa, Yasuhiro, Haba, Reiji, Kushida, Yoshio, Tamiya, Takashi, Nagao, Seigo

“…A 44-year-old man with a history of sudden onset short-term disorientation was admitted to our hospital. T2-weighted fast spin-echo MR images of the head…”
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Matrix metalloproteinase-2 and -9 expression in astrocytic tumors by Kunishio, Katsuzo, Okada, Masaki, Matsumoto, Yoshihito, Nagao, Seigo

“…In this study, we investigated whether the expression of matrix metalloproteinase (MMP)-2 and MMP-9 correlated with invasiveness, proliferative potential, or…”
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Resistance to topoisomerase II inhibitors in human glioma cell lines overexpressing multidrug resistant associated protein (MRP) 2 by Matsumoto, Yoshihito, Tamiya, Takashi, Nagao, Seigo

“…For understanding of the resistance to topoisomerase II inhibitors, 50 sublines were isolated as single clones from parental glioma cell lines by exposure to…”
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Prognostic implication of p27 expression in primary central nervous system lymphoma by Kunishio, Katsuzo, Nagao, Seigo

“…To clarify the role of p27/Kip1 (p27) in primary central nervous system lymphomas (PCNSLs), we examined p27 expression by immunohistochemical methods in a…”
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Crossed cerebellar glucose hypermetabolism demonstrated using PET in symptomatic epilepsy--case report by Kawai, Nobuyuki, Kawanishi, Masahiko, Tamiya, Takashi, Nagao, Seigo

“…A 65-year-old male with an old cerebral contusion in the frontal lobes had suffered from status complex partial seizures. Ictal positron emission tomography…”
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Technetium-99m sestamibi single photon emission computed tomography findings correlated with P-glycoprotein expression in pituitary adenoma by Kunishio, Katsuzo, Okada, Maski, Matsumoto, Yoshihito, Nagao, Seigo, Nishiyama, Yoshihiro

“…The aim of this study is to evaluate whether the technetium-99m sestamibi (99mTc-MIBI) single photon emission computed tomography (SPECT) characteristics of…”
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Reduction of expression of the multidrug resistance protein (MRP)1 in glioma cells by antisense phosphorothioate oligonucleotides by Matsumoto, Yoshihito, Miyake, Keisuke, Kunishio, Katsuzou, Tamiya, Takashi, Nagao, Seigo

“…The tumor cells’ acquisition of resistance to multiple drugs due to overexpression of the multidrug resistance protein (MRP) 1 gene is one of major obstacles…”
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