Search Results - "NAG, Kakon"
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Glycosylation regulates pannexin intermixing and cellular localization
Published in Molecular biology of the cell (15-10-2009)“…The pannexin family of mammalian proteins, composed of Panx1, Panx2, and Panx3, has been postulated to be a new class of single-membrane channels with…”
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2
DoE-derived continuous and robust process for manufacturing of pharmaceutical-grade wide-range LNPs for RNA-vaccine/drug delivery
Published in Scientific reports (07-06-2022)“…Lipid nanoparticle (LNP) technology has become extremely demanding for delivering RNA-products and other drugs. However, there is no platform to manufacture…”
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3
An Engineered N-Cadherin Substrate for Differentiation, Survival, and Selection of Pluripotent Stem Cell-Derived Neural Progenitors
Published in PloS one (05-08-2015)“…For stem cell-based treatment of neurodegenerative diseases a better understanding of key developmental signaling pathways and robust techniques for producing…”
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4
Antiviral Activity of Trappin-2 and Elafin In Vitro and In Vivo against Genital Herpes
Published in Journal of Virology (01-07-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Satisfying QTPP of Erythropoietin Biosimilar by QbD through DoE-Derived Downstream Process Engineering
Published in Pharmaceutics (01-08-2023)“…Well-characterized and scalable downstream processes for the purification of biologics are extremely demanding for delivering quality therapeutics to patients…”
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6
A novel knowledge-derived data potentizing method revealed unique liver cancer-associated genetic variants
Published in Human genomics (04-07-2019)“…Next-generation sequencing (NGS) has been advancing the progress of detection of disease-associated genetic variants and genome-wide profiling of expressed…”
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7
Calcitonin receptor-like receptor (CLR) influences posttranslational events of receptor activity-modifying proteins (RAMPs)
Published in Biochemical and biophysical research communications (24-02-2012)“…► CLR can modify post translational properties of RAMP. ► These modifications are crucial for pharmacological properties of relevant receptor. ► RAMP can be…”
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8
Milk matters: soluble Toll-like receptor 2 (sTLR2) in breast milk significantly inhibits HIV-1 infection and inflammation
Published in PloS one (06-07-2012)“…The majority of infants who breastfeed from their HIV-positive mothers remain uninfected despite constant and repeated exposure to virus over weeks to years…”
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9
Anti-HIV-1 Activity of Elafin Is More Potent than Its Precursor's, Trappin-2, in Genital Epithelial Cells
Published in Journal of Virology (01-04-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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10
Anti-HIV-1 activity of elafin depends on its nuclear localization and altered innate immune activation in female genital epithelial cells
Published in PloS one (27-12-2012)“…Elafin (E) and its precursor trappin-2 (Tr) are alarm antiproteases with antimicrobial and immunomodulatory activities. Tr and E (Tr/E) have been associated…”
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11
Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C
Published in PloS one (24-04-2012)“…Upon viral recognition, innate and adaptive antiviral immune responses are initiated by genital epithelial cells (ECs) to eradicate or contain viral infection…”
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12
Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression
Published in Proceedings of the National Academy of Sciences - PNAS (25-03-2008)“…Heart development is a precisely coordinated process of cellular proliferation, migration, differentiation, and integrated morphogenetic interactions, and…”
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13
Molecular and functional characterization of adrenomedullin receptors in pufferfish
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-02-2006)“…The receptors for the calcitonin gene-related peptide (CGRP)/adrenomedullin (AM) family peptides were characterized in the mefugu Takifugu obscurus, a…”
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14
A novel type of urea transporter, UT-C, is highly expressed in proximal tubule of seawater eel kidney
Published in American journal of physiology. Renal physiology (01-03-2005)“…A new type of urea transporter was identified by a database search and shown to be highly expressed in the renal proximal tubule cells of teleosts; proximal…”
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15
Fish calcitonin receptor has novel features
Published in General and comparative endocrinology (01-10-2007)“…Abstract Calcitonin (CT), a 32-amino acid peptide, was initially isolated from fish. Fish CT has higher affinity to mammalian CT receptor (CTR), and has…”
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16
An mRNA-based vaccine candidate against SARS-CoV-2 elicits stable immuno-response with single dose
Published in Vaccine (23-06-2021)“…D614G genotype of SARS-CoV-2 virus is highly infectious and responsible for almost all infection for 2nd wave. However, there are currently no reports with…”
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Characterization of the zebrafish cx36.7 gene promoter: Its regulation of cardiac-specific expression and skeletal muscle-specific repression
Published in Gene (15-02-2016)“…Zebrafish connexin 36.7 (cx36.7/ecx) has been identified as a key molecule in the early stages of heart development in this species. A defect in cx36.7 causes…”
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18
Milk Matters: Soluble Toll-Like Receptor 2
Published in PloS one (06-07-2012)“…The majority of infants who breastfeed from their HIV-positive mothers remain uninfected despite constant and repeated exposure to virus over weeks to years…”
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19
Ligand-induced internalization, recycling, and resensitization of adrenomedullin receptors depend not on CLR or RAMP alone but on the receptor complex as a whole
Published in General and comparative endocrinology (01-02-2015)“…Highlights • All combinations of AM receptors (CLR–RAMP) were quickly internalized after ligand induction. • Recycling rates of the internalized CLR–RAMP…”
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20
Headless splice variant acting as dominant negative calcitonin receptor
Published in Biochemical and biophysical research communications (03-11-2007)“…Calcitonin receptor (CTR) is a member of class B G protein-coupled receptor (GPCR) superfamily. We have recently identified the CTR gene and its two…”
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