Search Results - "NAFFAKH, N"

A Genetically Engineered Waterfowl Influenza Virus with a Deletion in the Stalk of the Neuraminidase Has Increased Virulence for Chickens by Munier, S, Larcher, T, Cormier-Aline, F, Soubieux, D, Su, B, Guigand, L, Labrosse, B, Cherel, Y, Quéré, P, Marc, D, Naffakh, N

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A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors by Chen, K.Y., Krischuns, T., Varga, L. Ortega, Harigua-Souiai, E., Paisant, S., Zettor, A., Chiaravalli, J., Delpal, A., Courtney, D., O'Brien, A., Baker, S.C., Decroly, E., Isel, C., Agou, F., Jacob, Y., Blondel, A., Naffakh, N.

“…Effective drugs against SARS-CoV-2 are urgently needed to treat severe cases of infection and for prophylactic use. The main viral protease (nsp5 or 3CLpro)…”
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Length Variations in the NA Stalk of an H7N1 Influenza Virus Have Opposite Effects on Viral Excretion in Chickens and Ducks by HOFFMANN, T. W, MUNIER, S, VOLMER, R, NAFFAKH, N, MARC, D, LARCHER, T, SOUBIEUX, D, LEDEVIN, M, ESNAULT, E, TOURDES, A, CROVILLE, G, GUERIN, J.-L, QUERE, P

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Natural Variation Can Significantly Alter the Sensitivity of Influenza A (H5N1) Viruses to Oseltamivir by RAMEIX-WELTI, M. A, AGOU, F, BUCHY, P, MARDY, S, AUBIN, J. T, VERON, M, VAN DER WERF, S, NAFFAKH, N

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In vitro characterization of naturally occurring influenza H3NA− viruses lacking the NA gene segment: Toward a new mechanism of viral resistance? by Moules, V, Ferraris, O, Terrier, O, Giudice, E, Yver, M, Rolland, J.P, Bouscambert-Duchamp, M, Bergeron, C, Ottmann, M, Fournier, E, Traversier, A, Boule, C, Rivoire, A, Lin, Y, Hay, A, Valette, M, Marquet, R, Rosa-Calatrava, M, Naffakh, N, Schoehn, G, Thomas, D, Lina, B

“…Abstract Among a panel of 788 clinical influenza H3N2 isolates, two isolates were characterized by an oseltamivir-resistant phenotype linked to the absence of…”
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Highly heterogeneous temperature sensitivity of 2009 pandemic influenza A(H1N1) viral isolates, northern France by Pelletier, I, Rousset, D, Enouf, V, Colbere-Garapin, F, van der Werf, S, Naffakh, N

“…We assayed the temperature sensitivity of 2009 pandemic influenza A(H1N1) viral isolates (n=23) and seasonal influenza A(H1N1) viruses (n=18) isolated in…”
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Sustained Delivery of Erythropoietin in Mice by Genetically Modified Skin Fibroblasts by Naffakh, N., Henri, A., Villeval, J. L., Rouyer-Fessard, P., Moullier, P., Blumenfeld, N., Danos, O., Vainchenker, W., Heard, J. M., Beuzard, Y.

“…We have examined whether the secretion of erythropoietin (Epo) from genetically modified cells could represent an alternative to repeated injections of the…”
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Binding of the hemagglutinin from human or equine influenza H3 viruses to the receptor is altered by substitutions at residue 193 by Medeiros, R, Naffakh, N, Manuguerra, J.C, Werf, S. van der

“…Interactions of the hemagglutinin (HA) of influenza viruses with sialic acids (SA) are important for host range restriction. Most human H3s have a Ser193,…”
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Long-term secretion of therapeutic proteins from genetically modified skeletal muscles by Naffakh, N, Pinset, C, Montarras, D, Li, Z, Paulin, D, Danos, O, Heard, J M

“…Protein delivery from genetically modified skeletal muscle has been reported previously. However, a stable and prolonged secretion was obtained in…”
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Disappearance of Lysosomal Storage in Spleen and Liver of Mucopolysaccharidosis VII Mice After Transplantation of Genetically Modified Bone Marrow Cells by Maréchal, Valérie, Naffakh, Nadia, Danos, Olivier, Heard, Jean Michel

“…Mice homozygous for the gusmps allele lack β-glucuronidase activity and provide a useful model for human Mucopolysaccharidosis type VII (MPS VII), also known…”
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Tribute to Frédéric Morinet by Naffakh, N., Girard, M., Perette-Ficaja, A.

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Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells by Labadie, Karine, Dos Santos Afonso, Emmanuel, Rameix-Welti, Marie-Anne, van der Werf, Sylvie, Naffakh, Nadia

“…Abstract The transcription/replication activity of ribonucleoproteins derived from influenza A primary isolates of human (A/Paris/908/97) or avian origin…”
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Residue 627 of PB2 Is a Determinant of Cold Sensitivity in RNA Replication of Avian Influenza Viruses by Massin, P, van der Werf, S, Naffakh, N

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Développement et applications de la génétique inverse des virus grippaux by NAFFAKH, N, DOS SANTOS, E. A, ESCRIOU, N, VAN DER WERF, S

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Cloning of the Chicken RNA Polymerase I Promoter and Use for Reverse Genetics of Influenza A Viruses in Avian Cells by MASSIN, Pascale, RODRIGUES, Pierre, MARASESCU, Monica, VAN DER WERF, Sylvie, NAFFAKH, Nadia

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Hemagglutinin Residues of Recent Human A(H3N2) Influenza Viruses That Contribute to the Inability to Agglutinate Chicken Erythrocytes by Medeiros, Rita, Escriou, Nicolas, Naffakh, Nadia, Manuguerra, Jean-Claude, van der Werf, Sylvie

“…To identify the molecular determinants contributing to the inability of recent human influenza A(H3N2) viruses to agglutinate chicken erythrocytes, phenotypic…”
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Macrophage colony-stimulating factor: serum levels and cDNA structure in malignant osteopetrosis [letter] by Naffakh, N, Le Gall, S, Danos, O, Heard, JM, Cournot, G, Motoyoshi, K, Vilmer, E

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The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5′ end of the PB2 segment by Dos Santos Afonso, Emmanuel, Escriou, Nicolas, Leclercq, India, van der Werf, Sylvie, Naffakh, Nadia

“…We generated recombinant A/WSN/33 influenza A viruses expressing a PB2 protein fused to a Flag epitope at the N- (Flag-PB2) or C-terminus (PB2-Flag), which…”
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Transplantation of adult-derived myoblasts in mice following gene transfer by Naffakh, N, Pinset, C, Montarras, D, Pastoret, C, Danos, O, Heard, J M

“…We have explored the use of myoblasts obtained from adult animals as a target for somatic gene therapy. Myoblasts from an adult beta-glucuronidase deficient…”
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Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses by Naffakh, Nadia, Massin, Pascale, Escriou, Nicolas, Crescenzo-Chaigne, Bernadette, van der Werf, Sylvie

“…Unité de Génétique Moléculaire des Virus Respiratoires, URA CNRS 1966, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France 1 Author for…”
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