Search Results - "NADEL, A"

Lesion of striatal patches disrupts habitual behaviors and increases behavioral variability by Nadel, Jacob A, Pawelko, Sean S, Copes-Finke, Della, Neidhart, Maya, Howard, Christopher D

“…Habits are automated behaviors that are insensitive to changes in behavioral outcomes. Habitual responding is thought to be mediated by the striatum, with…”
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Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases by Burgel, P-R, Nadel, J. A

“…Inhaled air is contaminated with pathogens and particulates that may deposit in the airways and damage the host. In response to these invaders, the airway…”
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Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium by Kalinowski, A, Galen, B T, Ueki, I F, Sun, Y, Mulenos, A, Osafo-Addo, A, Clark, B, Joerns, J, Liu, W, Nadel, J A, Dela Cruz, C S, Koff, J L

“…Respiratory syncytial virus (RSV) persists as a significant human pathogen that continues to contribute to morbidity and mortality. In children, RSV is the…”
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Dual Oxidase 1-Dependent MUC5AC Mucin Expression in Cultured Human Airway Epithelial Cells by Matt X. G. Shao, Nadel, Jay A., Clements, John A.

“…Mucus hypersecretion is a prominent manifestation in patients with chronic inflammatory airway diseases. MUC5AC mucin is a major component of airway mucus, and…”
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Isolated abnormal FEF75% detects unsuspected bronchiolar obstruction in CF children by Masson, Vicki K., Nussbaum, Eliezer, Gelb, Arthur F., Tashkin, Donald P., Randhawa, Inderpal, Nadel, Jay A., Fireizen, Yaron, De Celie-Germana, Joan K., Madera, Danielle, Senanayake, Dinithi

“…Background Physiologic detection of bronchiolar obstruction in children with cystic fibrosis (CF) may be clinically unsuspected because of normal routine…”
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Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium by Koff, Jonathan L, Shao, Matt X G, Ueki, Iris F, Nadel, Jay A

“…Toll-like receptors (TLRs) are critical for the recognition of inhaled pathogens that deposit on the airway epithelial surface. The epithelial response to…”
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Chronic Ethanol Consumption Alters Presynaptic Regulation of Dorsal Striatal Dopamine Release in C57BL/6J Mice by Salinas, Armando G., Nadel, Jacob A., Mateo, Yolanda, Huynh, Thanh, Augustin, Shana M., Pacak, Karel, Lovinger, David M.

“…Alcohol use disorder (AUD) is characterized by escalating alcohol consumption, preoccupation with alcohol, and continued alcohol consumption despite adverse…”
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CCL20/CCR6 feedback exaggerates epidermal growth factor receptor-dependent MUC5AC mucin production in human airway epithelial (NCI-H292) cells by Kim, Suil, Lewis, Courtney, Nadel, Jay A

“…Mucous hypersecretion is an important feature of obstructive airway diseases such as asthma, chronic obstructive pulmonary disease, and cystic fibrosis…”
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Optogenetic stimulation of striatal patches modifies habit formation and inhibits dopamine release by Nadel, J. A., Pawelko, S. S., Scott, J. R., McLaughlin, R., Fox, M., Ghanem, M., van der Merwe, R., Hollon, N. G., Ramsson, E. S., Howard, C. D.

“…Habits are inflexible behaviors that develop after extensive repetition, and overreliance on habits is a hallmark of many pathological states. The striatum is…”
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EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production by Kalinowski, April, Ueki, Iris, Min-Oo, Gundula, Ballon-Landa, Eric, Knoff, David, Galen, Benjamin, Lanier, Lewis L, Nadel, Jay A, Koff, Jonathan L

“…Airway epithelial cells are the primary cell type involved in respiratory viral infection. Upon infection, airway epithelium plays a critical role in host…”
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Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium by Burgel, P-R, Nadel, J A

“…The epithelial cells lining the airways serve protective functions. The “barrier function” of the epithelium protects the individual from damage by inhaled…”
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A morphometric study of mucins and small airway plugging in cystic fibrosis by Burgel, Pierre-Régis, Montani, David, Danel, Claire, Dusser, Daniel J, Nadel, Jay A

“…Rationale: Little knowledge exists on structural changes and plugging in small airways in cystic fibrosis. Objective: To characterise the extent of plugging…”
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Understanding the pathophysiology of the asthma–chronic obstructive pulmonary disease overlap syndrome by Gelb, Arthur F, Christenson, Stephanie A, Nadel, Jay A

“…PURPOSE OF REVIEWThe review will provide an update on the pathophysiology and studies of inflammation associated with the asthma–chronic obstructive pulmonary…”
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Does previa location matter? Surgical morbidity associated with location of a placenta previa by Young, B C, Nadel, A, Kaimal, A

“…Objective: To evaluate the effect of placenta previa location (anterior vs posterior) on cesarean morbidity. Study Design: Retrospective cohort of women…”
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Affirmation of the adoration of the vagi and role of tiotropium in asthmatic patients by Gelb, Arthur F., MD, Nadel, Jay A., MD

“…In their discussion they noted that sympathetic neural pathways are sparse in human lungs and have their endings on cells of the cholinergic postganglionic…”
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Understanding the pathophysiology of the asthma–chronic obstructive pulmonary disease overlap syndrome by Gelb, Arthur F., MD, Nadel, Jay A., MD

“…The unexpected loss of lung elastic recoil in nonsmoking asthmatic patients contributes greatly to exaggerate any expiratory airflow limitation because of…”
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Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells by Kim, Suil, Beyer, Brittney A, Lewis, Courtney, Nadel, Jay A

“…Mutations in cystic fibrosis transmembrane conductance regulator (CFTR) protein cause cystic fibrosis, a disease characterized by exaggerated airway epithelial…”
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Relationship of epidermal growth factor receptors to goblet cell production in human bronchi by TAKEYAMA, Kiyoshi, FAHY, John V, NADEL, Jay A

“…To determine the relationship of epidermal growth factor receptor (EGFR) expression to mucin synthesis in human airways, we examined EGFR and MUC5AC expression…”
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Tumor Necrosis Factor α-Converting Enzyme Mediates MUC5AC Mucin Expression in Cultured Human Airway Epithelial Cells by Matt X. G. Shao, Ueki, Iris F., Nadel, Jay A.

“…Ectodomain shedding of epidermal growth factor receptor (EGFR) ligands [e.g., transforming growth factor type α(TGF-α)] and EGFR phosphorylation are implicated…”
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OP05.10: Sex chromosome aneuploidy: pregnancy outcomes for patients with a positive screen by Goldfarb, I., Nadel, A., Bromley, B.

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