Search Results - "NADEAU, KRISTEN J."

Age-related consequences of childhood obesity by Kelsey, Megan M, Zaepfel, Alysia, Bjornstad, Petter, Nadeau, Kristen J

“…The severity and frequency of childhood obesity has increased significantly over the past three to four decades. The health effects of increased body mass…”
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Fructose and sugar: A major mediator of non-alcoholic fatty liver disease by Jensen, Thomas, Abdelmalek, Manal F., Sullivan, Shelby, Nadeau, Kristen J., Green, Melanie, Roncal, Carlos, Nakagawa, Takahiko, Kuwabara, Masanari, Sato, Yuka, Kang, Duk-Hee, Tolan, Dean R., Sanchez-Lozada, Laura G., Rosen, Hugo R., Lanaspa, Miguel A., Diehl, Anna Mae, Johnson, Richard J.

“…Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome; its rising prevalence parallels the rise in obesity and diabetes…”
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Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes by Vinovskis, Carissa, Li, Lu-Ping, Prasad, Pottumarthi, Tommerdahl, Kalie, Pyle, Laura, Nelson, Robert G, Pavkov, Meda E, van Raalte, Daniel, Rewers, Marian, Pragnell, Marlon, Mahmud, Farid H, Cherney, David Z, Johnson, Richard J, Nadeau, Kristen J, Bjornstad, Petter

“…The objective of this study was to compare the ratio of renal oxygen availability (RO ) to glomerular filtration rate (GFR), a measure of relative renal…”
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Childhood obesity and cardiovascular disease: links and prevention strategies by Nadeau, Kristen J, Maahs, David M, Daniels, Stephen R, Eckel, Robert H

“…The prevalence and severity of obesity among children has increased dramatically over the past 30 years. Strong evidence supports the concept that precursors…”
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Hepatic steatosis relates to gastrointestinal microbiota changes in obese girls with polycystic ovary syndrome by Jobira, Beza, Frank, Daniel N, Silveira, Lori J, Pyle, Laura, Kelsey, Megan M, Garcia-Reyes, Yesenia, Robertson, Charles E, Ir, Diana, Nadeau, Kristen J, Cree-Green, Melanie

“…Hepatic steatosis (HS) is common in adolescents with obesity and polycystic ovary syndrome (PCOS). Gut microbiota are altered in adults with obesity, HS, and…”
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Continuous Glucose Monitoring and its Relationship to Hemoglobin A1c and Oral Glucose Tolerance Testing in Obese and Prediabetic Youth by Chan, Christine L, Pyle, Laura, Newnes, Lindsey, Nadeau, Kristen J, Zeitler, Philip S, Kelsey, Megan M

“…Context: The optimal screening test for diabetes and prediabetes in obese youth is controversial. Objective: We examined whether glycosylated hemoglobin…”
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Mathematical modeling reveals differential dynamics of insulin action models on glycerol and glucose in adolescent girls with obesity by Hampton, Griffin S, Bartlette, Kai, Nadeau, Kristen J, Cree-Green, Melanie, Diniz Behn, Cecilia

“…Under healthy conditions, the pancreas responds to a glucose challenge by releasing insulin. Insulin suppresses lipolysis in adipose tissue, thereby decreasing…”
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Estimated Insulin Sensitivity and Cardiovascular Disease Risk Factors in Adolescents with and without Type 1 Diabetes by Specht, Brian J., BS, Wadwa, R. Paul, MD, Snell-Bergeon, Janet K., PhD, Nadeau, Kristen J., MD, Bishop, Franziska K., MS, Maahs, David M., MD

“…Objective To test the hypothesis that cardiovascular disease (CVD) risk factors are similar in nondiabetic (non-DM) adolescents compared with those with type 1…”
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Respecting tribal voices in the development of a gestational diabetes risk reduction preconception counseling program for American Indian/Alaska Native adolescent females: a qualitative study by Moore, Kelly R, Stotz, Sarah A, Terry, Martha Ann, Seely, Ellen W, Gonzales, Kelly, Marshall, Gale, Nadeau, Kristen J, Akers, Aletha, Garcia-Reyes, Yesenia, Charron-Prochownik, Denise

“…American Indians and Alaska Natives (AI/AN) are disproportionately affected by adolescent obesity, adolescent pregnancy and gestational diabetes mellitus…”
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Insulin sensitivity, body composition and bone mineral density after testosterone treatment in transgender youth with and without prior GnRH agonist therapy by Nokoff, Natalie J., Bothwell, Samantha, Rice, John D., Cree, Melanie G., Kelsey, Megan M., Moreau, Kerrie L., Zeitler, Philip, Nadeau, Kristen J.

“…1.8% of youth identify as transgender; a growing proportion are transgender male (female sex, male gender identity). Many receive gonadotropin releasing…”
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Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP) by Shah, Amy S, Helmrath, Michael A, Inge, Thomas H, Xanthakos, Stavra A, Kelsey, Megan M, Jenkins, Todd, Trout, Andrew T, Browne, Lorna, Nadeau, Kristen J

“…IntroductionThe pathophysiology of type 2 diabetes (T2D) in youth differs from adults and conventional medical treatment approaches with lifestyle change,…”
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Relationship of Cardiac Structure and Function to Cardiorespiratory Fitness and Lean Body Mass in Adolescents and Young Adults with Type 2 Diabetes by Bacha, Fida, MD, Gidding, Samuel S., MD, Pyle, Laura, PhD, Levitt Katz, Lorraine, MD, Kriska, Andrea, PhD, Nadeau, Kristen J., MD, MS, Lima, Joao A.C., MD

“…Objective To investigate the relationships of cardiac structure and function with body composition and cardiorespiratory fitness (CRF) among adolescents with…”
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Cardiopulmonary Dysfunction and Adiponectin in Adolescents With Type 2 Diabetes by Bjornstad, Petter, Truong, Uyen, Dorosz, Jennifer L., Cree‐Green, Melanie, Baumgartner, Amy, Coe, Gregory, Pyle, Laura, Regensteiner, Judith G., Reusch, Jane E. B., Nadeau, Kristen J.

“…Background Myocardial mechanics are altered in adults with obesity and type 2 diabetes (T2D); insulin resistance and adipokines have been implicated as…”
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Effect of metformin on the high‐density lipoprotein proteome in youth with type 1 diabetes by Gourgari, Evgenia, Nadeau, Kristen J., Pyle, Laura, Playford, Martin P., Ma, Junfeng, Mehta, Nehal N., Remaley, Alan T., Gordon, Scott M.

“…Background Youth with type 1 diabetes (T1D) have normal or elevated High‐Density Lipoprotein Cholesterol (HDL‐C), however, the function of HDL, partly mediated…”
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Elevated Serum Uric Acid Is Associated With Greater Risk for Hypertension and Diabetic Kidney Diseases in Obese Adolescents With Type 2 Diabetes: An Observational Analysis From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study by Bjornstad, Petter, Laffel, Lori, Lynch, Jane, El Ghormli, Laure, Weinstock, Ruth S, Tollefsen, Sherida E, Nadeau, Kristen J

“…Elevated serum uric acid (SUA) is increasingly recognized as a risk factor for kidney disease in adults with diabetes, but data in youth are limited. We…”
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Fasting plasma metabolomic profiles are altered by three days of standardized diet and restricted physical activity by Pyle, Laura, Carreau, Anne-Marie, Rahat, Haseeb, Garcia-Reyes, Yesenia, Bergman, Bryan C., Nadeau, Kristen J., Cree-Green, Melanie

“…Few studies have examined the effects of participants’ diet and activity prior to sample collection on metabolomics profiles, and results have been…”
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Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration by Bartlette, Kai, Carreau, Anne-Marie, Xie, Danielle, Garcia-Reyes, Yesenia, Rahat, Haseeb, Pyle, Laura, Nadeau, Kristen J., Cree-Green, Melanie, Diniz Behn, Cecilia

“…The Oral Minimal Model (OMM), a differential-equations based mathematical model of glucose-insulin dynamics, utilizes data from a frequently sampled oral…”
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Acute Hyperinsulinemia Alters Bone Turnover in Women and Men With Type 1 Diabetes by Sherk, Vanessa D, Vigers, Timothy, Pyle, Laura, Snell‐Bergeon, Janet K, Nadeau, Kristen J, Rickels, Michael R, Miller, Kellee M, Greenbaum, Carla J, Shah, Viral N

“…ABSTRACT Type 1 diabetes (T1D) increases fracture risk across the lifespan. The low bone turnover associated with T1D is thought to be related to glycemic…”
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Targeting mitochondria to restore failed adaptation to exercise in diabetes by Geary, Kate, Knaub, Leslie A, Schauer, Irene E, Keller, Amy C, Watson, Peter A, Miller, Matthew W, Garat, Chrystelle V, Nadeau, Kristen J, Cree-Green, Melanie, Pugazhenthi, Subbiah, Regensteiner, Judith G, Klemm, Dwight J, Reusch, Jane E B

“…Our translational research group focuses on addressing the problem of exercise defects in diabetes with basic research efforts in cell and rodent models and…”
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The changing face of paediatric diabetes by Shah, Amy S., Nadeau, Kristen J.

“…The purpose of this review is to provide an update on the changing face of paediatric type 1 diabetes and type 2 diabetes. Paediatric diabetes is on the rise,…”
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