Search Results - "NADAF, Sorena"

Precision medicine and actionable alterations in lung cancer: A single institution experience by Mambetsariev, Isa, Wang, Yingyu, Chen, Chen, Nadaf, Sorena, Pharaon, Rebecca, Fricke, Jeremy, Amanam, Idoroenyi, Amini, Arya, Bild, Andrea, Chu, Peiguo, Erhunmwunsee, Loretta, Kim, Jae, Munu, Janet, Pillai, Raju, Raz, Dan, Sampath, Sagus, Vora, Lalit, Qiu, Fang, Smith, Lynette, Batra, Surinder K, Massarelli, Erminia, Koczywas, Marianna, Reckamp, Karen, Salgia, Ravi

“…Oncology has become more reliant on new testing methods and a greater use of electronic medical records, which provide a plethora of information available to…”
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Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation by Dikov, Mikhail M, Ohm, Joyce E, Ray, Neelanjan, Tchekneva, Elena E, Burlison, Jared, Moghanaki, Drew, Nadaf, Sorena, Carbone, David P

“…Impaired Ag-presenting function in dendritic cells (DCs) due to abnormal differentiation is an important mechanism of tumor escape from immune control. A major…”
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Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo by GABRILOVICH, D, ISHIDA, T, OYAMA, T, RAN, S, KRAVTSOV, V, NADAF, S, CARBONE, D. P

“…Defective function of dendritic cells (DC) in cancer has been recently described and may represent one of the mechanisms of tumor evasion from immune system…”
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Clinical Significance of Defective Dendritic Cell Differentiation in Cancer by Almand, B, Resser, J R, Lindman, B, Nadaf, S, Clark, J I, Kwon, E D, Carbone, D P, Gabrilovich, D I

“…Defective dendritic cell (DC) function has been described previously in cancer patients and tumor-bearing mice. It can be an important factor in the escape of…”
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Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of Multiple Hematopoietic Lineages In Vivo by Gabrilovich, Dmitry, Ishida, Tadao, Oyama, Tsunehiro, Ran, Sophia, Kravtsov, Vladimir, Nadaf, Sorena, Carbone, David P.

“…Defective function of dendritic cells (DC) in cancer has been recently described and may represent one of the mechanisms of tumor evasion from immune system…”
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Antibodies to Vascular Endothelial Growth Factor Enhance the Efficacy of Cancer Immunotherapy by Improving Endogenous Dendritic Cell Function by GABRILOVICH, D. I, ISHIDA, T, NADAF, S, OHM, J. E, CARBONE, D. P

“…Inadequate function of dendritic cells (DCs) in tumor-bearing hosts is one mechanism of tumor escape from immune system control and may compromise the efficacy…”
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Immunization With Mutant p53- and K-ras–Derived Peptides in Cancer Patients: Immune Response and Clinical Outcome by CARBONE, David P, CIERNIK, I. Frank, PENDLETON, C. David, SEIFERT, Burkhardt, CARTER, Charley, READ, Elizabeth J, GREENBLATT, Jay, TOP, Lois E, KELSEY, Morris I, MINNA, John D, BERZOFSKY, Jay A, KELLEY, Michael J, SMITH, M. Charles, NADAF, Sorena, KAVANAUGH, Denise, MAHER, V. Ellen, STIPANOV, Michael, CONTOIS, David, JOHNSON, Bruce E

“…To determine the ability to induce tumor-specific immunity with individual mutant K-ras-or p53-derived peptides and to monitor clinical outcome. Patients in…”
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Costello and cardio-facio-cutaneous syndromes: Moving toward clinical trials in RASopathies by Rauen, Katherine A., Banerjee, Anuradha, Bishop, W. Robert, Lauchle, Jennifer O., McCormick, Frank, McMahon, Martin, Melese, Teri, Munster, Pamela N., Nadaf, Sorena, Packer, Roger J., Sebolt-Leopold, Judith, Viskochil, David H.

“…The RASopathies, one of the largest groups of multiple congenital anomaly syndromes known, are caused by germline mutations in various genes encoding…”
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Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells by Gabrilovich, Dmitry I, Chen, Hailei L, Girgis, Khaled R, Cunningham, H. Thomas, Meny, Geralyn M, Nadaf, Sorena, Kavanaugh, Denise, Carbone, David P

“…Inadequate presentation of tumor antigens by host professional antigen-presenting cells (APCs), including dendritic cells (DCs), is one potential mechanism for…”
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A Training-Testing Approach to the Molecular Classification of Resected Non-Small Cell Lung Cancer by YAMAGATA, Noboru, SHYR, Yu, JENSEN, Roy, LEVY, Shawn, MOORE, Jason H, MINNA, John D, CARBONE, David P, YANAGISAWA, Kiyoshi, EDGERTON, Mary, DANG, Thao P, GONZALEZ, Adriana, NADAF, Sorena, LARSEN, Paul, ROBERTS, John R, NESBITT, Jonathan C

“…Purpose: RNA expression patterns associated with non-small cell lung cancer subclassification have been reported, but there are substantial differences in the…”
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PRISM: Patient Records Interpretation for Semantic clinical trial Matching system using large language models by Gupta, Shashi, Basu, Aditya, Nievas, Mauro, Thomas, Jerrin, Wolfrath, Nathan, Ramamurthi, Adhitya, Taylor, Bradley, Kothari, Anai N., Schwind, Regina, Miller, Therica M., Nadaf-Rahrov, Sorena, Wang, Yanshan, Singh, Hrituraj

“…Clinical trial matching is the task of identifying trials for which patients may be eligible. Typically, this task is labor-intensive and requires detailed…”
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Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines by Adachi, Yasushi, Lee, Choon–Taek, Coffee, Keith, Yamagata, Noboru, Ohm, Joyce E., Park, Kyung–Ho, Dikov, Mikhail M., Nadaf, Sorena R., Arteaga, Carlos L., Carbone, David P.

“…Background & Aims: Insulin-like growth factor (IGF)-I receptor (IGF-Ir) signaling is required for maintenance of growth and tumorigenicity of several tumor…”
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H1° histone and differentiation of dendritic cells. A molecular target for tumor-derived factors by Gabrilovich, Dmitry I., Cheng, Pingyan, Fan, Yuhong, Yu, Bin, Nikitina, Ekaterina, Sirotkin, Allen, Shurin, Michael, Oyama, Tsunehiro, Adachi, Yasushi, Nadaf, Sorena, Carbone, David P., Skoultchi, Arthur I.

“…Dendritic cells (DC) play a central role in antitumor immune responses. Abnormal differentiation of DC and their inability to stimulate T cells are important…”
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A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer by Chen, Hailei L, Nadaf, Sorena, Girgis, Khaled R, Gabrilovich, Dmitry, Carbone, David P, Tampé, Robert

“…Tumours express a variety of novel epitopes which represent potential immune targets, and thus clinically evident tumours are thought to have effectively…”
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Structural and functional analysis of β2 microglobulin abnormalities in human lung and breast cancer by Chen, Hailei L., Gabrilovich, Dmitry, Virmani, Arvind, Ratnani, Ikki, Girgis, Khaled R., Nadaf‐Rahrov, Sorena, Fernandez‐Viña, Marcelo, Carbone, David P.

“…The escape of tumor cells from immune recognition is a central problem in tumor immunology. Here, we examined the functional role of somatic beta…”
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Precision medicine and actionable alterations in lung cancer by Mambetsariev, Isa, Nadaf, Sorena, Wang, Yingyu, Chen, Chen, Hewelt, Blake, Pharaon, Rebecca, Massarelli, Erminia, Koczywas, Marianna, Reckamp, Karen L., Salgia, Ravi

“…Abstract only e20707 Background: In recent years, healthcare centers have become more reliant on the advent of new technology, testing methods and a greater…”
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The City of Hope POSEIDON enterprise-wide platform for real-world data and evidence in cancer by Courdy, Samir, Hulse, Mark, Nadaf, Sorena, Mao, Allen, Pozhitkov, Alex, Berger, Stacy, Chang, Jack, Achuthan, Srisairam, Kancharla, Chetan, Kunz, Isaac, Peddinti, Ananth, Sarmiento, Raul, Seetharamu, Karthik, Kirkpatrick, Tarrah, Dilsizian, Bedros, Morris, Michael, Bonner, Joseph D., Gray, Stacy W., McDonnell, Kevin, Gruber, Stephen B

“…Abstract only e18813 Background: The City of Hope Center for Precision Medicine developed an enterprise-wide platform and precision medicine program to unlock…”
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VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression by Ohm, Joyce E., Gabrilovich, Dmitry I., Sempowski, Gregory D., Kisseleva, Ekaterina, Parman, Kelly S., Nadaf, Sorena, Carbone, David P.

“…T-cell defects and premature thymic atrophy occur in cancer patients and tumor-bearing animals. We demonstrate that exposure of mice to recombinant vascular…”
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Proteomic patterns of tumour subsets in non-small-cell lung cancer by Yanagisawa, Kiyoshi, Shyr, Yu, Xu, Baogang J, Massion, Pierre P, Larsen, Paul H, White, Bill C, Roberts, John R, Edgerton, Mary, Gonzalez, Adriana, Nadaf, Sorena, Moore, Jason H, Caprioli, Richard M, Carbone, David P

“…Proteomics-based approaches complement the genome initiatives and may be the next step in attempts to understand the biology of cancer. We used matrix-assisted…”
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Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells by Oyama, T, Ran, S, Ishida, T, Nadaf, S, Kerr, L, Carbone, D P, Gabrilovich, D I

“…Vascular endothelial growth factor (VEGF), produced by almost all tumor cells, affects the ability of hemopoietic progenitor cells (HPC) to differentiate into…”
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