Search Results - "N. V. Gukasova"

Obtaining and Studying the Antioxidant Activity and Hepatoprotective Effect of a Polymer Composition Containing Silybin by Kuznetsov, S L, Gukasova, N V, Tubasheva, I A, Zavarzina, V V, Aleshin, S V, Muraveva, A I, Lapin, A A, Zelenkov, V N, Poltavets Yu I

“…Preparations based on silybin are used as hepatoprotectors in the treatment of liver lesions of various etiologies. The main disadvantage limiting their use is…”
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Nano- and Microsized Forms of Silymarin and Silybin by Poltavets Yu I, Kuznetsov, S L, Tubasheva, I A, Murav’eva A I, Gukasova, N V

“…Modern preparations of milk thistle have been used since 1960−1970s. By their chemical nature, the active substances of milk thistle are flavonoids…”
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Formulation of perspective hepatoprotector polymeric forms based on silybin and ursodeoxycholic acid by Tereshchenko, O. G., Nikolskaya, E. D., Zhunina, O. A., Zavarzina, V. V., Yabbarov, N. G., Fomicheva, M. V., Zubkov, E. V., Sokol, M. B., Gukasova, N. V., Severin, E. S.

“…Silybin (Slb) and ursodeoxycholic acid (UDCA) are hepatoprotectors used in the pathogenetic therapy of liver and biliary tract. However, low bioavailability of…”
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Pharmacokinetics and Biodistribution of Anastrozole in a Polymer-Containing Formulation by Gukasova, N. V., Tubasheva, I. A., Kuznetsov, S. L., Aleshin, S. V., Sokolov, V. V., Antipova, T. A., Poltavets, Yu. I., Krasheninnikova, A. A., Vorontsov, E. A.

“…A polymer-containing anastrozole formulation (PAF) in the form of micronized particles based on a copolymer of lactic and glycolic acids with a terminal…”
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Development of a polymer system for the delivery of daunorubicin to tumor cells to overcome drug resistance by Nikolskaya, E. D., Faustova, M. R., Mollaev, M. D., Zhunina, O. A., Sokol, M. B., Yabbarov, N. G., Gukasova, N. V., Lobanov, A. V., Shvets, V. I., Severin, E. S.

“…Method for the synthesis of polymeric nanoparticles (NP) with encapsulated daunorubicin (DNR) was developed on the basis of double emulsion solvent evaporation…”
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Comparative Pharmacokinetics and Biodistribution of Etoposide in a Polymer Dosage Form and as Free Drug Substance by Gukasova, N. V., Tubasheva, I. A., Kuznetsov, S. L., Murav’eva, A. I., Aleshin, S. V., Sokolov, V. V., Antipova, T. A., Vorontsov, E. A.

“…A polymer dosage form of etoposide (PFE) was obtained as submicron particles based on the copolymer of lactic and glycolic acids (PLGA). Pharmacokinetics and…”
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The docetaxel polymeric form and its antitumor activity by Nikolskaya, E. D., Zhunina, O. A., Yabbarov, N. G., Tereshchenko, O. G., Godovannyy, A. V., Gukasova, N. V., Severin, E. S.

“…A new pharmaceutical form of the antitumor drug docetaxel (Dtx) has been developed based on a biodegradable copolymer of lactic and glycolic acids (PLGA…”
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New Protein Vector ApE1 for Targeted Delivery of Anticancer Drugs by Pozdniakova, N. V., Gorokhovets, N. V., Gukasova, N. V., Bereznikova, A. V., Severin, E. S.

“…A new chimeric gene ApE1 encoding the receptor-binding domain of the human alpha-fetoprotein fused to a sequence of 22 glutamic acid residues was constructed…”
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Targeted delivery of paclitaxel-loaded recombinant α-fetoprotein fragment-conjugated nanoparticles to tumor cells by Godovannyi, A. V., Vorontsov, E. A., Gukasova, N. V., Pozdnyakova, N. V., Vasilenko, E. A., Yabbarov, N. G., Dubovik, E. G., Severin, S. E., Severin, E. S., Gnuchev, N. V.

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Antitumor activity of alpha-fetoprotein conjugate with doxorubicin in vitro and in vivo by Feldman, N B, Kiselev, S M, Gukasova, N V, Posypanova, G A, Lutsenko, S V, Severin, S E

“…alpha-Fetoprotein (AFP) was conjugated with doxorubicin (DR) using glutaraldehyde as a cross-linking agent. The protein/DR molar ratio in the conjugate is 1 :…”
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Antitumor activity of alpha fetoprotein and epidermal growth factor conjugates in vitro and in vivo by Lutsenko, S V, Feldman, N B, Finakova, G V, Gukasova, N V, Petukhov, S P, Posypanova, G A, Skryabin, K G, Severin, S E

“…Conjugates of carminomycin (Cm) with alpha-fetoprotein (AFP) and epidermal growth factor (EGF) were prepared and their cytotoxic activities were studied in…”
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Localization of Mullerian inhibiting substance receptors in various human cancer cell lines by Rodina, A. V., Gukasova, N. V., Makarov, V. A., Kondrasheva, I. G., Khomyakova, A. V., Posypanova, G. A., Popova, O. N., Moskaleva, E. Yu, Severin, S. E.

“…Recombinant human MIS (rhMIS) produced in transfected Chinese hamster ovary cells has been purified by immunoaffinity chromatography. In the absence of…”
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Cytotoxic action of conjugates of alpha-fetoprotein and epidermal growth factor with photoheme, chlorines, and phthalocyanines by Savitsky, A A, Gukasova, N V, Gumanov, S G, Feldman, N B, Luk'yanets, E A, Mironov, A F, Yakubovskaya, R I, Lutsenko, S V, Severin, S E

“…Covalently bound conjugates of alpha-fetoprotein (AFP) and epidermal growth factor (EGF) with photoheme (PH), 3-desvinyl-3-formylchlorine p6 (Chl p6), chlorine…”
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Antibacterial Activity of the Polymeric Form of Josamycin by E. D. Nikolskaya, O. A. Zhunina, M. B. Sokol, M. V. Fomicheva, N. V. Gukasova, E. A. Vorontsov, N. G. Yabbarov, O. G. Tereshchenko, E. S. Severin

“…The polymeric form ofjosamycin was developed by loading of the antibiotic into spherical submicron particles made of poly(DL- lactide-co-glycolide) (PLGA…”
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Design of etoposide polymeric forms by Murav’eva, A. I., Vorontsov, E. A., Gukasova, N. V., Zavarzina, V. V., Kuznetsov, S. L., Tubasheva, I. A., Semochkina, Yu. P., Moskaleva, E. Yu, Posypanova, G. A., Severin, S. E.

“…The present work relates to the field of pharmacology and medicine, in particular, to a new generation of anticancer drugs based on biocompatible polymers…”
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Antitumor activity of targeted nanosome delivery systems based on poly(lactic-co-glycolic acid) nanoparticles, paclitaxel, and a recombinant alpha-fetoprotein fragment by Godovannyi, A. V., Vorontsov, E. A., Gukasova, N. V., Pozdnyakova, N. V., Vasilenko, E. A., Yabbarov, N. G., Severin, S. E., Severin, E. S., Gnuchev, N. V.

“…Biodegradable polymeric nanoparticles conjugated with targeting vector molecules have become prospective agents to improve the effectiveness of…”
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Targeted delivery of paclitaxel-loaded recombinant [alpha]-fetoprotein fragment-conjugated nanoparticles to tumor cells by Godovannyi, A V, Vorontsov, E A, Gukasova, N V, Pozdnyakova, N V, Vasilenko, E A, Yabbarov, N G, Dubovik, E G, Severin, S E, Severin, E S, Gnuchev, N V

“…Godovannyi et al previously proposed a method for targeted delivery of cytotoxic drugs into tumor cells using alpha fetoprotein (AFP) as a vector molecule…”
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