Search Results - "N. V. Cherdyntseva"

EpCAM-CD24+ circulating cells associated with poor prognosis in breast cancer patients by Perelmuter, V. M., Grigoryeva, E. S., Savelieva, O. E., Alifanov, V. V., Andruhova, E. S., Zavyalova, M. V., Bragina, O. D., Garbukov, E. Yu, Menyailo, M. E., Khozyainova, A. A., Denisov, E. V., Cherdyntseva, N. V., Tashireva, L. A.

“…Following the discovery of circulating tumor cells (CTCs) in the peripheral blood of cancer patients, CTCs were initially postulated to hold promise as a…”
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Molecular subtype conversion in CTCs as indicator of treatment adequacy associated with metastasis-free survival in breast cancer by Grigoryeva, E. S., A.Tashireva, L., Alifanov, V. V., Savelieva, O. E., Vtorushin, S. V., Zavyalova, M. V., Bragina, O. D., Garbukov, E. Y., Cherdyntseva, N. V., Choinzonov, E. L., Perelmuter, V. M.

“…Molecular subtype of breast cancer has a great clinical significance and used as one of the major criteria for therapeutic strategy. Recently, for anticancer…”
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DNA methylome analysis reveals potential alterations contributing to the progression of bronchial hyperplasia by Ponomaryova, A. A., Schegoleva, A. A., Gervas, P. A., Pancova, O. V., Gerashchenko, T. S., Zarubin, A. A., Perelmuter, V. M., Cherdyntseva, N. V., Denisov, E. V.

“…Background Squamous cell lung cancer (SCLC) arises from bronchial changes: basal cell hyperplasia (BCH), squamous metaplasia (SM), and dysplasia. However, the…”
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Analysis of Methylome of Different Forms of Basal Cell Hyperplasia and Squamous Cell Metaplasia of Bronchial Epithelium by Ponomaroyva, A. A., Schegoleva, A. A., Gervas, P. A., Gerashchenko, T. S., Pankova, O. V., Ershov, N. I., Perelmuter, V. M., Cherdyntseva, N. V., Denisov, E. V.

“…Squamous cell lung cancer (SCLC) occurs as a result of dysregenerative changes in the bronchial epithelium: basal cell hyperplasia (BCH), squamous cell…”
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Preparation of a Single-Cell Suspension from Tumor Biopsy Samples for Single-Cell RNA Sequencing by Frolova, A. A., Gerashchenko, T. S., Patysheva, M. R., Fedorov, A. A., Tsyganov, M. M., Bokova, U. A., Bragina, O. D., Vostrikova, M. A., Garbukov, E. Yu, Cherdyntseva, N. V.

“…An essential requirement for single-cell RNA sequencing in cancer is the preparation of high-quality single-cell suspensions from the tumor tissue. In this…”
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Do tumor exosome integrins alone determine organotropic metastasis? by Grigoryeva, E. S., Savelieva, O. E., Popova, N. O., Cherdyntseva, N. V., Perelmuter, V. M.

“…Metastasis is the most life-threatening event in cancer patients, so the key strategy to treat cancer should be preventing tumor spread. Predicting the site of…”
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Integration of phosphoinositide 3-kinase (PI3K) and transforming growth factor β1 (TGF-β1) signaling cascades: role in the therapeutic inefficiency of tamoxifen by Babyshkina, N. N., Uzyanbaev,  I.  A., Dronova,  T.  A., Cherdyntseva, N. V.

“…Growth factors signaling cascades and their interaction with the central regulatory targets of tumor cells and estrogens are considered as the main mechanisms…”
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Predicting the site of distant metastases in breast cancer by Grigoryeva, E. S., Ivanyuk, E. E., Choinzonov, E. L., Cherdyntseva, N. V.

“…Background. Distant organ tumor dissemination is a major cause of breast cancer-related deaths. Breast cancer can metastasize to several organs, and the most…”
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The 45th anniversary of Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences by Choinzonov, E. L., Nekrylov, S. A., Cherdyntseva, N. V., Chernov, V. I., Goldberg, V. E.

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Microbiome, immune system and cancer: three sides of the one medal by Belyavskaya, V. A., Cherdyntseva, N. V., Kzhyshkovska, J. G., Litvyakov, N. V.

“…Purpose of the study to analyze current ideas about the relationship between the microbiota (microbiome) and the human body in the aspect of cancer…”
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Intratumor heterogeneity: Nature and biological significance by Gerashchenko, T. S., Denisov, E. V., Litviakov, N. V., Zavyalova, M. V., Vtorushin, S. V., Tsyganov, M. M., Perelmuter, V. M., Cherdyntseva, N. V.

“…Intratumor heterogeneity inherent in the majority of human cancers is a major obstacle for a highly efficient diagnosis and successful prognosis and treatment…”
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Genotoxic Effects of New Azoloazine Derivatives with Antitumor Activity in MCF-7 Tumor Cell Culture by Al-Humain, A. H., Speranskiy, D. L., Rybalkina, O. Yu, Sadchikova, E. V., Buldakov, M. A., Frolova, A. A., Cherdyntseva, N. V., Udut, V. V.

“…The genotoxic properties of three new azoloazine derivatives (azoloazines 1 – 3 ) exhibiting cytotoxic activity were studied in an in vitro experiment using…”
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Effect of new antitumor compounds based on azoloazine derivatives on the level of DNA damage in normal Vero cells in the DNA comet test by Al-Humairi, A. H., Speranskiy, D. L., Minakova, M. Yu, Cherdyntseva, N. V., Udut, V. V.

“…The aim of the work is to study the effect of new azoloazine derivatives on the level of DNA damage to Vero cells (DNA comet test) in vitro by alkaline gel…”
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Immune-phenotyping and transcriptomic profiling of blood monocytes from patients with breast cancer under neoadjuvant chemotherapy by Patysheva, M. R., Stakheyeva, M. N., Grigoryeva, E. S., Iamshchikov, P. S., Larionova, I. V., Budnickya, А. A., Tarabanovskaya, N. A., Cherdyntseva, N. V., Kzhyshkowska, J. G.

“…Introduction. Chemotherapy is a common treatment for breast cancer. Chemotherapeutic drugs effect blood monocytes, which are major contributors to cancer…”
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Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Contributes to Tamoxifen Resistance in Estrogen-Positive Breast Cancer Patients by Dronova, T. A., Babyshkina, N. N., Zavyalova, M. V., Slonimskaya, E. M., Cherdyntseva, N. V.

“…Crosstalk between the estrogen receptors and the receptor tyrosine kinases, including vascular endothelial growth factor receptor type II (VEGFR2), is a key…”
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Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Contributes to Tamoxifen Resistance in Estrogen-Positive Breast Cancer Patients by Dronova, T A, Babyshkina, N N, Zavyalova, M V, Slonimskaya, E M, Cherdyntseva, N V

“…Crosstalk between the estrogen receptors and the receptor tyrosine kinases, including vascular endothelial growth factor receptor type II (VEGFR2), is a key…”
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Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects by Cherdyntseva, N V, Litviakov, N V, Denisov, E V, Gervas, P A, Cherdyntsev, E S

“…Each patient has a unique history of cancer ecosystem development, resulting in intratumor heterogeneity. In order to effectively kill the tumor cells by…”
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Phenotypic profle of monocyte-macrophage lineage cells as a function of respiratory epithelium status by Fedorov, A. A., Ermak, N. A., Topolnitskiy, E. B., Shefer, N. A., Rodionov, E. O., Pankova, O. V., Cherdyntseva, N. V., Stakheyeva, M. N.

“…The mechanism of the relationship between pretumor changes in the bronchial respiratory epithelium and the risk of progression of non-small cell lung cancer…”
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The phenomenon of multi-drug resistance in the treatment of malignant tumors by Vtorushin, S V, Khristenko, K Y, Zavyalova, M V, Perelmuter, V M, Litviakov, N V, Denisov, E V, Dulesova, A Y, Cherdyntseva, N V

“…Multi-drug resistance (MDR) is a condition when there is broad cross-resistance of cells to various agents which are different in structure and effect. Modern…”
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Antitumor activity of three new azoloazine derivatives in orthotopic transplantation model of human breast cancer cells into mice by Al-Humairi, A. H., Speransky, D. L., Novochadov, V. V., Poroisky, S. V., Cherdyntseva, N. V., Udut, V. V.

“…Breast cancer (BC) is one of the most common types of malignant tumors, which makes scientific research in this area extremely relevant. The difficulties of…”
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