Search Results - "N. A. C. S. Wong"

CDX1 Is an Important Molecular Mediator of Barrett's Metaplasia by N. A. C. S. Wong, Wilding, J., Bartlett, S., Liu, Y., Warren, B. F., Piris, J., Maynard, N., Marshall, R., Bodmer, W. F.

“…The molecular pathogenesis of Barrett's metaplasia (BM) of the esophagus is poorly understood. The change to an intestinal phenotype occurs on a background of…”
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Interobserver variation in the classification of tumor deposits in rectal cancer—is the use of histopathological characteristics the way to go? by Brouwer, Nelleke P. M., Lord, A. C., Terlizzo, M., Bateman, A. C., West, N. P., Goldin, R., Martinez, A., Wong, N. A. C. S., Novelli, M., Nagtegaal, I. D., Brown, G.

“…The focus on lymph node metastases (LNM) as the most important prognostic marker in colorectal cancer (CRC) has been challenged by the finding that other types…”
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Loss of CDX1 Expression in Colorectal Carcinoma: Promoter Methylation, Mutation, and Loss of Heterozygosity Analyses of 37 Cell Lines by N. A. C. S. Wong, Britton, M. P., Choi, G. S., Stanton, T. K., Bicknell, D. C., Wilding, J. L., Bodmer, W. F.

“…Expression of the homeobox protein CDX1 is lost or reduced in a significant proportion of colorectal carcinomas (CRCs) but the underlying mechanism for this is…”
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Colorectal neoplasia in ulcerative colitis-recent advances by Wong, N A C S, Harrison, D J

“…Colorectal neoplasia in ulcerative colitis—recent advances It is recognized that ulcerative colitis (UC) predisposes to the development of colorectal…”
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Immunohistochemical assessment of Ki67 and p53 expression assists the diagnosis and grading of ulcerative colitis-related dysplasia by Wong, N A C S, Mayer, N J, MacKell, S, Gilmour, H M, Harrison, D J

“…Aims : To assess whether Ki67 and p53 immunostaining may assist the diagnosis and grading of ulcerative colitis‐related dysplasia. Methods and results :…”
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Subepithelial apoptosis in normal caecal biopsy specimens is primarily an age-related phenomenon by Wong, N A C S, Jenkins, R, Reid, G J

“…Aims:  To determine whether prominent subepithelial apoptosis in otherwise normal caecal endoscopic biopsy specimens has any clinical significance. Methods and…”
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EpCAM and gpA33 are markers of Barrett’s metaplasia by Wong, N A C S, Warren, B F, Piris, J, Maynard, N, Marshall, R, Bodmer, W F

“…Aims: To characterise a specific and sensitive marker of Barrett’s metaplasia (BM). Methods: Cases of normal oesophageal squamous mucosa (11 fresh endoscopic…”
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Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma by WONG, N. A. C. S, BRETT, L, STEWART, M, LEITCH, A, LONGLEY, D. B, DUNLOP, M. G, JOHNSTON, P. G, LESSELLS, A. M, JODRELL, D. I

“…Thymidylate synthase (TS) is a key enzyme in DNA synthesis and is inhibited by metabolites of the chemotherapeutic agent 5-fluorouracil (5FU). Nuclear…”
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Outcome reporting in neoadjuvant surgical trials: a systematic review of the literature and proposals for new standards by Blencowe, N S, Chana, P, Whistance, R N, Stevens, D, Wong, N A C S, Falk, S J, Blazeby, J M

“…The use of neoadjuvant therapy before surgery for gastrointestinal cancer is increasing; however, patients may not complete both treatment components…”
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Clinicopathological and molecular study of penile melanoma by Oxley, J D, Corbishley, C, Down, L, Watkin, N, Dickerson, D, Wong, N A C S

“…To examine the clinicopathological features of a series of penile melanomas and screen for mutations in the BRAF and KIT genes, which are seen in melanomas…”
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Prognostic indicators for gastrointestinal stromal tumours: a clinicopathological and immunohistochemical study of 108 resected cases of the stomach by Wong, N A C S, Young, R, Malcomson, R D G, Nayar, A G, Jamieson, L A, Save, V E, Carey, F A, Brewster, D H, Han, C, Al-Nafussi, A

“…Aims:  Whether immunohistochemical markers increase accuracy in predicting prognosis for gastrointestinal stromal tumours (GISTs) remains uncertain. However,…”
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Cutaneous metastasis from gastric glomus tumour by Bray, A. P. J. J., Wong, N. A. C. S., Narayan, S.

“…Summary A 58‐year‐old man presented with a 4‐month history of a rapidly enlarging asymptomatic tumour on the scalp vertex. Six years earlier, the patient had…”
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KIT and PDGFRα mutational analyses of mixed cell-type gastrointestinal stromal tumours by Wong, N A C S, Mangwana, S

“…Aims:  To determine whether the epithelioid and spindle components of a mixed cell‐type gastrointestinal stromal tumour (GIST) show the same receptor tyrosine…”
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Positive immunostaining for thyroid transcription factor-1 in colorectal adenocarcinoma using the 8G7G3/1 monoclonal antibody by Wong, N A C S, Kamel, H, Sheffield, E A, Sohail, M

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Specificity of intra-acinar necrosis as a marker of colorectal liver metastasis by Wong, N A C S, Neville, L P

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Epstein-Barr virus infection in colorectal neoplasms associated with inflammatory bowel disease: detection of the virus in lymphomas but not in adenocarcinomas by Wong, NACS, Herbst, H, Herrmann, K, Kirchner, T, Krajewski, AS, Moorghen, M, Niedobitek, F, Rooney, N, Shepherd, NA, Niedobitek, G

“…Epstein–Barr virus (EBV) is associated with several lymphoid and epithelial human malignancies. The latter include gastric adenocarcinomas, while sporadic…”
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Mast cell-rich leiomyomas should not be mistaken for gastrointestinal stromal tumours by Wong, N A C S, Pawade, J

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Cyclin D1 overexpression in colorectal carcinoma in vivo is dependent on β-catenin protein dysregulation, but not k-ras mutation by Wong, N. A. C. S., Morris, R. G., McCondochie, A., Bader, S., Jodrell, D. I., Harrison, D. J.

“…Cyclin D1 protein overexpression is commonly found in colorectal carcinomas (CRCs) and is associated with a poorer prognosis, but the mechanism underlying…”
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Intra-abdominal spindle cell lesions: a review and practical aids to diagnosis by Al-Nafussi, A, Wong, N A C S

“…Intra‐abdominal spindle cell lesions: a review and practical aids to diagnosis Intra‐abdominal spindle cell lesions are uncommon and often present a diagnostic…”
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Randomly amplified polymorphic DNA typing: a useful tool for rapid epidemiological typing of Klebsiella pneumoniae by Wong, N. A. C. S., Linton, C. J., Jalal, H., Millar, M. R.

“…Discriminatory typing methods are invaluable in the investigation of outbreaks of infectious diseases. Single primers were used to generate randomly amplified…”
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