Search Results - "N Zara"

Impact of clinically unsuspected venous thrombotic events on CVC removal and survival in pediatric cancer patients: A population-based study from the Maritimes, Canada by MacDonald, Emma E., Forbrigger, Zara N., Ells, Brett, MacDonald, Tamara, Goldenberg, Neil A., Kulkarni, Ketan

“…Venous thromboembolism (VTE) is a well-recognized complication in pediatric cancer patients. We aimed to determine the frequency of central venous catheter…”
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High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo by Zara, Janette N, Siu, Ronald K, Zhang, Xinli, Shen, Jia, Ngo, Richard, Lee, Min, Li, Weiming, Chiang, Michael, Chung, Jonguk, Kwak, Jinny, Wu, Benjamin M, Ting, Kang, Soo, Chia

“…The major Food and Drug Association-approved osteoinductive factors in wide clinical use are bone morphogenetic proteins (BMPs). Although BMPs can promote…”
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NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation by Chang, Jia, Liu, Fei, Lee, Min, Wu, Benjamin, Ting, Kang, Zara, Janette N., Soo, Chia, Hezaimi, Khalid Al, Zou, Weiping, Chen, Xiaohong, Mooney, David J., Wang, Cun-Yu

“…Mesenchymal stem cell (MSC)-based transplantation is a promising therapeutic approach for bone regeneration and repair. In the realm of therapeutic bone…”
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A new function of Nell-1 protein in repressing adipogenic differentiation by James, Aaron W., Pan, Angel, Chiang, Michael, Zara, Janette N., Zhang, Xinli, Ting, Kang, Soo, Chia

“…► Nell-1 is a potent pro-osteogenic molecule, but has not yet been studied systematically in adipogenic differentiation. ► Using 3T3-L1 cells and primary human…”
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Tinnitus Evaluation in Type 1 Diabetes Mellitus at Tertiary Hospital Malaysia by Ameen, S A, Norasyikin, A W, Dina, H Noor, Zara, M N Fahrin, Tyler, R, Asma, Abdullah

“…To determine the prevalence of tinnitus in Type 1 Diabetes Mellitus (T1DM) patients, to evaluate its severity and to correlate it with estimated Glomerular…”
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Cutting Edge: The Transcription Factor Sox2 Regulates AID Expression in Class-Switched B Cells by DiMenna, Lauren J, Yen, Wei-Feng, Nicolas, Laura, Sharma, Rahul, Saldanha, Zara N, Chaudhuri, Jayanta

“…IgH class switch recombination (CSR) occurs through the deliberate introduction of activation-induced cytidine deaminase (AID)-instigated DNA double-strand…”
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The Nell-1 growth factor stimulates bone formation by purified human perivascular cells by Zhang, Xinli, Péault, Bruno, Chen, Weiwei, Li, Weiming, Corselli, Mirko, James, Aaron W, Lee, Min, Siu, Ronald K, Shen, Pang, Zheng, Zhong, Shen, Jia, Kwak, Jinny, Zara, Janette N, Chen, Feng, Zhang, Hong, Yin, Zack, Wu, Ben, Ting, Kang, Soo, Chia

“…The search for novel sources of stem cells other than bone marrow mesenchymal stem cells (MSCs) for bone regeneration and repair has been a critical endeavor…”
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Nfatc2 is a primary response gene of nell‐1 regulating chondrogenesis in ATDC5 cells by Chen, Weiwei, Zhang, Xinli, Siu, Ronald K, Chen, Feng, Shen, Jia, Zara, Janette N, Culiat, Cymbeline T, Tetradis, Sotirios, Ting, Kang, Soo, Chia

“…Nell‐1 is a growth factor required for normal skeletal development and expression of extracellular matrix proteins required for bone and cartilage cell…”
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NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation by Zou, Xuan, Shen, Jia, Chen, Feng, Ting, Kang, Zheng, Zhong, Pang, Shen, Zara, Janette N., Adams, John S., Soo, Chia, Zhang, Xinli

“…► We constructed a cDNA library of Saos2 cells to identify NELL-1 interacting proteins. ► APR3 was identified as a direct binding protein of NELL-1 through…”
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Development of a highly efficacious vaccinia-based dual vaccine against smallpox and anthrax, two important bioterror entities by Merkel, Tod J., Perera, Pin-Yu, Kelly, Vanessa K., Verma, Anita, Llewellyn, Zara N., Waldmann, Thomas A., Mosca, Joseph D., Perera, Liyanage P.

“…Bioterrorism poses a daunting challenge to global security and public health in the 21st century. Variola major virus, the etiological agent of smallpox, and…”
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NELL-1 promotes cartilage regeneration in an in vivo rabbit model by Siu, Ronald K, Zara, Janette N, Hou, Yaping, James, Aaron W, Kwak, Jinny, Zhang, Xinli, Ting, Kang, Wu, Benjamin M, Soo, Chia, Lee, Min

“…Repair of cartilage due to joint trauma remains challenging due to the poor healing capacity of cartilage and adverse effects related to current growth…”
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NELL-1, an osteoinductive factor, is a direct transcriptional target of Osterix by Chen, Feng, Zhang, Xinli, Sun, Shan, Zara, Janette N, Zou, Xuan, Chiu, Robert, Culiat, Cymbelin T, Ting, Kang, Soo, Chia

“…NELL-1 is a novel secreted protein associated with premature fusion of cranial sutures in craniosynostosis that has been found to promote osteoblast cell…”
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Abstract No. 117: CT scan follow-up after endovascular abdominal aortic aneurysm repair (EVAR). Is volumetry better compared to D-max for detection of failures and successes? by Zara, N, Soulez, G

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NELL-1 injection maintains long-bone quantity and quality in an ovariectomy-induced osteoporotic senile rat model by Kwak, Jinny, Zara, Janette N, Chiang, Michael, Ngo, Richard, Shen, Jia, James, Aaron W, Le, Khoi M, Moon, Crystal, Zhang, Xinli, Gou, Zhongru, Ting, Kang, Soo, Chia

“…Over 10 million Americans have osteoporosis, and is the predominant cause of fractures in the elderly. Treatment of fractures in the setting of osteoporosis is…”
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NELL-1 based demineralized bone graft promotes rat spine fusion as compared to commercially available BMP-2 product by Dong, Jian, Yuan, Wei, Shen, Jia, Tian, Hai Jun, Wang, Jeffrey C., Zhang, Xinli, James, Aaron W., Zara, Janette N., Asatrian, Greg, Siu, Ronald K.

“…Spinal fusion is among the most commonly performed orthopaedic procedures. Unfortunately, current treatments such as autologous bone grafting or recombinant…”
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The antimicrobial and osteoinductive properties of silver nanoparticle/poly ( dl -lactic- co- glycolic acid)-coated stainless steel by Liu, Yi, Zheng, Zhong, Zara, Janette N, Hsu, Chingyun, Soofer, Donnalisa E, Lee, Kevin S, Siu, Ronald K, Miller, Lloyd S, Zhang, Xinli, Carpenter, Doug, Wang, Chunling, Ting, Kang, Soo, Chia

“…Abstract Implant-associated bacterial infections are one of the most serious complications in orthopedic surgery. Treatment of these infections often requires…”
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Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2 by Shen, Jia, James, Aaron W, Zhang, Xinli, Pang, Shen, Zara, Janette N, Asatrian, Greg, Chiang, Michael, Lee, Min, Khadarian, Kevork, Nguyen, Alan, Lee, Kevin S, Siu, Ronald K, Tetradis, Sotirios, Ting, Kang, Soo, Chia

“…The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein…”
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The use of BMP-2 coupled – Nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects by Zheng, Zhong, Yin, Wei, Zara, Janette N, Li, Weiming, Kwak, Jinny, Mamidi, Rachna, Lee, Min, Siu, Ronald K, Ngo, Richard, Wang, Joyce, Carpenter, Doug, Zhang, Xinli, Wu, Benjamin, Ting, Kang, Soo, Chia

“…Abstract Healing of contaminated/infected bone defects is a significant clinical challenge. Prevalence of multi-antibiotic resistant organisms has renewed…”
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Reprogramming of human fibroblasts into multipotent cells with a single ECM proteoglycan, fibromodulin by Zheng, Zhong, Jian, Jia, Zhang, Xinli, Zara, Janette N, Yin, Wei, Chiang, Michael, Liu, Yi, Wang, Joyce, Pang, Shen, Ting, Kang, Soo, Chia

“…Abstract Pluripotent and/or multipotent stem cell-based therapeutics are a vital component of tissue engineering and regenerative medicine. The generation or…”
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Fibromodulin reduces scar size and increases scar tensile strength in normal and excessive‐mechanical‐loading porcine cutaneous wounds by Jiang, Wenlu, Ting, Kang, Lee, Soonchul, Zara, Janette N., Song, Richard, Li, Chenshuang, Chen, Eric, Zhang, Xinli, Zhao, Zhihe, Soo, Chia, Zheng, Zhong

“…Hypertrophic scarring is a major postoperative complication which leads to severe disfigurement and dysfunction in patients and usually requires multiple…”
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