Primary osteosarcoma of breast - A clinical camouflage: Case report

Primary osteosarcoma of breast - A clinical camouflage: Case report

Primary sarcoma of the breast is a rare clinical entity with an incidence of less than 1% among cases of breast cancer. Primary osteosarcoma of the breast is a very rare disease that shares clinical features similar to metaplastic breast carcinoma. A 57-year-old female Dravidian patient presented wi...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics Vol. 19; no. 7; pp. 2064 - 2066
Main Authors: Bandegudda, Santhoshkumar, N Raju, Kvv, Kodandapani, Suseela, Rao, Jayakartik
Format: Journal Article
Language:English
Published: India Medknow Publications and Media Pvt. Ltd 01-10-2023
Medknow Publications & Media Pvt. Ltd
Subjects:
Biopsy
Bone cancer
Breast cancer
Care and treatment
Case reports
Diagnosis
Lumpectomy
Mammography
Osteosarcoma
Sarcoma
India
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Summary:Primary sarcoma of the breast is a rare clinical entity with an incidence of less than 1% among cases of breast cancer. Primary osteosarcoma of the breast is a very rare disease that shares clinical features similar to metaplastic breast carcinoma. A 57-year-old female Dravidian patient presented with a breast lump. A needle biopsy was suggestive of carcinoma. However, the mammogram was suggestive of dense calcification lesion, which is unusual in carcinoma. She underwent breast conservation surgery with sentinel lymph node biopsy; final histopathology was suggestive of osteosarcoma of the breast. After a follow-up of 18 months, the patient is healthy and disease-free. Primary breast osteosarcoma has to be considered as one of the differential diagnoses to metaplastic carcinoma and warrants a different treatment approach. Whenever there is discordance in clinical features, imaging, and histology, thorough evaluation with the mammogram, immunohistochemistry, and PET scan helps to resolve the issue.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.jcrt_1689_21