Search Results - "N M Ijzermans, Jan"

Tissue-specific mutation accumulation in human adult stem cells during life by Blokzijl, Francis, de Ligt, Joep, Jager, Myrthe, Sasselli, Valentina, Roerink, Sophie, Sasaki, Nobuo, Huch, Meritxell, Boymans, Sander, Kuijk, Ewart, Prins, Pjotr, Nijman, Isaac J., Martincorena, Inigo, Mokry, Michal, Wiegerinck, Caroline L., Middendorp, Sabine, Sato, Toshiro, Schwank, Gerald, Nieuwenhuis, Edward E. S., Verstegen, Monique M. A., van der Laan, Luc J. W., de Jonge, Jeroen, IJzermans, Jan N. M., Vries, Robert G., van de Wetering, Marc, Stratton, Michael R., Clevers, Hans, Cuppen, Edwin, van Boxtel, Ruben

“…Stem cells of the liver, colon and small intestine gradually accumulate mutations throughout life at a similar rate even though cancer incidence varies greatly…”
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Early Recurrence After Liver Resection for Colorectal Metastases: Risk Factors, Prognosis, and Treatment. A LiverMetSurvey-Based Study of 6,025 Patients by Viganò, Luca, Capussotti, Lorenzo, Lapointe, Réal, Barroso, Eduardo, Hubert, Catherine, Giuliante, Felice, Ijzermans, Jan N. M., Mirza, Darius F., Elias, Dominique, Adam, René

“…Purpose The aims of this study were to assess the risk of early recurrence after liver resection for colorectal metastases (CRLM) and its prognostic value;…”
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Prognostic significance of the controlling nutritional status (CONUT) score in patients undergoing hepatectomy for hepatocellular carcinoma: a systematic review and meta-analysis by Takagi, Kosei, Domagala, Piotr, Polak, Wojciech G, Buettner, Stefan, Ijzermans, Jan N M

“…The clinical value of the controlling nutritional status (CONUT) score in hepatocellular carcinoma (HCC) has increased. The aim of this meta-analysis was to…”
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Cryptogenic non-cirrhotic HCC: Clinical, prognostic and immunologic aspects of an emerging HCC etiology by Beudeker, Boris J. B., Guha, Rael, Stoyanova, Kalina, IJzermans, Jan N. M., de Man, Robert A., Sprengers, Dave, Boonstra, Andre

“…The incidence of hepatocellular carcinoma (HCC) in non-cirrhotic livers is rising significantly, but clear risk factors for screening remain elusive. This…”
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Evaluation of Liver Graft Donation After Euthanasia by van Reeven, Marjolein, Gilbo, Nicholas, Monbaliu, Diethard, van Leeuwen, Otto B, Porte, Robert J, Ysebaert, Dirk, van Hoek, Bart, Alwayn, Ian P J, Meurisse, Nicolas, Detry, Olivier, Coubeau, Laurent, Cicarelli, Olga, Berrevoet, Frederik, Vanlander, Aude, IJzermans, Jan N M, Polak, Wojciech G

“…The option of donating organs after euthanasia is not well known. Assessment of the results of organ transplants with grafts donated after euthanasia is…”
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Onset of Donor Warm Ischemia Time in Donation After Circulatory Death Liver Transplantation: Hypotension or Hypoxia? by Kalisvaart, Marit, Haan, Jubi E., Polak, Wojciech G., N. M. IJzermans, Jan, Gommers, Diederik, Metselaar, Herold J., Jonge, Jeroen

“…The aim of this study was to investigate the impact of hypoxia and hypotension during the agonal phase of donor warm ischemia time (DWIT) on hepatic…”
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Actual survival after resection of primary colorectal cancer: results from a prospective multicenter study by van den Berg, Inge, Coebergh van den Braak, Robert R J, van Vugt, Jeroen L A, Ijzermans, Jan N M, Buettner, Stefan

“…Colorectal cancer is the third most common type of cancer in the world. We characterize a cohort of patients who survived up to 5 years without recurrence and…”
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Laparoscopic versus open peritoneal dialysis catheter insertion: a meta-analysis by Hagen, Sander M, Lafranca, Jeffrey A, Steyerberg, Ewout W, IJzermans, Jan N M, Dor, Frank J M F

“…Peritoneal dialysis is an effective treatment for end-stage renal disease. Key to successful peritoneal dialysis is a well-functioning catheter. The different…”
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Outcome of Microscopic Incomplete Resection (R1) of Colorectal Liver Metastases in the Era of Neoadjuvant Chemotherapy by Ayez, Ninos, Lalmahomed, Zarina S., Eggermont, Alexander M. M., Ijzermans, Jan N. M., de Jonge, Jeroen, van Montfort, Kees, Verhoef, Cornelis

“…Background Data from patients with colorectal liver metastases (CRLM) who received neoadjuvant chemotherapy before resection were reviewed and evaluated to see…”
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Prediction of Early Recurrence After Surgery for Liver Tumor (ERASL): An International Validation of the ERASL Risk Models by Beumer, Berend R., Takagi, Kosei, Vervoort, Bastiaan, Buettner, Stefan, Umeda, Yuzo, Yagi, Takahito, Fujiwara, Toshiyoshi, Steyerberg, Ewout W., IJzermans, Jan N. M.

“…Background This study aimed to assess the performance of the pre- and postoperative early recurrence after surgery for liver tumor (ERASL) models at external…”
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Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids by Roest, Henk P, IJzermans, Jan N M, van der Laan, Luc J W

“…Extracellular microRNAs (miRNAs), released from cells into biofluids, have emerged as promising biomarkers for diagnostic and prognostic purposes. Several RNA…”
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A proof of concept study on real-time LiMAx CYP1A2 liver function assessment of donor grafts during normothermic machine perfusion by Schurink, Ivo J., de Haan, Jubi E., Willemse, Jorke, Mueller, Matteo, Doukas, Michael, Roest, Henk, de Goeij, Femke H. C., Polak, Wojciech G., Ijzermans, Jan N. M., Dutkowski, Philipp, van der Laan, Luc J. W., de Jonge, Jeroen

“…No single reliable parameter exists to assess liver graft function of extended criteria donors during ex-vivo normothermic machine perfusion (NMP). The liver…”
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KRAS and BRAF mutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue by Mostert, Bianca, Jiang, Yuqiu, Sieuwerts, Anieta M., Wang, Haiying, Bolt‐de Vries, Joan, Biermann, Katharina, Kraan, Jaco, Lalmahomed, Zarina, Galen, Anne, Weerd, Vanja, Spoel, Petra, Ramírez‐Moreno, Raquel, Verhoef, Cornelis, IJzermans, Jan N.M., Wang, Yixin, Gratama, Jan‐Willem, Foekens, John A., Sleijfer, Stefan, Martens, John W.M.

“…Although anti‐EGFR therapy has established efficacy in metastatic colorectal cancer, only 10‐20% of unselected patients respond. This is partly due to KRAS and…”
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Low skeletal muscle mass is associated with increased hospital expenditure in patients undergoing cancer surgery of the alimentary tract by van Vugt, Jeroen L A, Buettner, Stefan, Levolger, Stef, Coebergh van den Braak, Robert R J, Suker, Mustafa, Gaspersz, Marcia P, de Bruin, Ron W F, Verhoef, Cornelis, van Eijck, Casper H C, Bossche, Niek, Groot Koerkamp, Bas, IJzermans, Jan N M

“…Low skeletal muscle mass is associated with poor postoperative outcomes in cancer patients. Furthermore, it is associated with increased healthcare costs in…”
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Attitudes among transplant professionals regarding shifting paradigms in eligibility criteria for live kidney donation by Lafranca, Jeffrey A, Spoon, Emerentia Q W, van de Wetering, Jacqueline, IJzermans, Jan N M, Dor, Frank J M F

“…The transplant community increasingly accepts extended criteria live kidney donors, however, great (geographical) differences are present in policies regarding…”
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Preoperative fasting protects against renal ischemia-reperfusion injury in aged and overweight mice by Jongbloed, Franny, de Bruin, Ron W F, Pennings, Jeroen L A, Payán-Gómez, César, van den Engel, Sandra, van Oostrom, Conny T, de Bruin, Alain, Hoeijmakers, Jan H J, van Steeg, Harry, IJzermans, Jan N M, Dollé, Martijn E T

“…Ischemia-reperfusion injury (IRI) is inevitable during kidney transplantation leading to oxidative stress and inflammation. We previously reported that…”
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Mannan-Binding Lectin Is Involved in the Protection against Renal Ischemia/Reperfusion Injury by Dietary Restriction by Shushimita, Shushimita, van der Pol, Pieter, W F de Bruin, Ron, N M Ijzermans, Jan, van Kooten, Cees, Dor, Frank J M F

“…Preoperative fasting and dietary restriction offer robust protection against renal ischemia/reperfusion injury (I/RI) in mice. We recently showed that…”
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Independent risk factors for urological complications after deceased donor kidney transplantation by Slagt, Inez K B, Ijzermans, Jan N M, Visser, Laurents J, Weimar, Willem, Roodnat, Joke I, Terkivatan, Türkan

“…Urological complications after kidney transplantation are mostly related to the ureteroneocystostomy, often requiring interventions with additional costs,…”
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Disruption of clock gene expression in human colorectal liver metastases by Huisman, Sander A., Ahmadi, Ali R., IJzermans, Jan N. M., Verhoef, Cees, van der Horst, Gijsbertus T. J., de Bruin, Ron W. F.

“…The circadian timing system controls about 40 % of the transcriptome and is important in the regulation of a wide variety of biological processes including…”
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A panel of DNA methylation markers for the classification of consensus molecular subtypes 2 and 3 in patients with colorectal cancer by Berg, Inge, Smid, Marcel, Coebergh van den Braak, Robert R. J., Wiel, Mark A., Deurzen, Carolien H. M., Weerd, Vanja, Martens, John W. M., IJzermans, Jan N. M., Wilting, Saskia M.

“…Consensus molecular subtypes (CMSs) can guide precision treatment of colorectal cancer (CRC). We aim to identify methylation markers to distinguish between…”
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