Search Results - "Núñez, Marvin J"

Anti-trypanosomal Lignans Isolated from Salvadoran Peperomia pseudopereskiifolia by Castillo, Ulises G., Uekusa, Yoshinori, Nishimura, Takehiro, Kiuchi, Fumiyuki, Martínez, Morena L., Menjívar, Jenny, Nakajima-Shimada, Junko, Núñez, Marvin J., Kikuchi, Haruhisa

“…A search for anti-trypanosomal natural compounds from plants collected in El Salvador, a country particularly endemic for Chagas disease, resulted in the…”
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Withanolide-Type Steroids from Physalis nicandroides Inhibit HIV Transcription by Taddeo, Vito A, Núñez, Marvin J, Beltrán, Manuela, Castillo, Ulises G, Menjívar, Jenny, Jiménez, Ignacio A, Alcamí, José, Bedoya, Luis M, Bazzocchi, Isabel L

“…The aim of the present study is to report the isolation, structural elucidation, and antiviral evaluation of four new withanolide-type steroids, named…”
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Latin American databases of natural products: biodiversity and drug discovery against SARS-CoV-2 by Núñez, Marvin J, Díaz-Eufracio, Bárbara I, Medina-Franco, José L, Olmedo, Dionisio A

“…In this study, we evaluated 3444 Latin American natural products using cheminformatic tools. We also characterized 196 compounds for the first time from the…”
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Isolation of Acacetin from Calea urticifolia with Inhibitory Properties against Human Monoamine Oxidase‑A and -B by Chaurasiya, Narayan D, Gogineni, Vedanjali, Elokely, Khaled M, León, Francisco, Núñez, Marvin J, Klein, Michael L, Walker, Larry A, Cutler, Stephen J, Tekwani, Babu L

“…Calea urticifolia (Asteraceae: Asteroideae) has long been used as a traditional medicine in El Salvador to treat arthritis and fever, among other illnesses…”
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Multistage Detection of Tetrodotoxin Traces in Diodon hystrix Collected in El Salvador by Fuentes-Monteverde, Juan Carlos, Núñez, Marvin J, Amaya-Monterosa, Oscar, Martínez, Morena L, Rodríguez, Jaime, Jiménez, Carlos

“…This study describes a multistage methodology to detect minute amounts of tetrodotoxin in fishes, a plan that may be broadened to include other marine…”
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Computationally aided stereochemical assignment of undescribed bisabolenes from Calea urticifolia by Gogineni, Vedanjali, Nael, Manal A., León, Francisco, Núñez, Marvin J., Cutler, Stephen J.

“…Calea urticifolia (Mill.) DC. (Compositae) is a medicinal plant found in El Salvador. Calea is used in folkloric medicine as a psychoactive principle with…”
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In Vitro Susceptibility of Kinetoplastids to Celastroloids from Maytenus chiapensis by Núñez, Marvin J, Martínez, Morena L, López-Arencibia, Atteneri, Bethencourt-Estrella, Carlos J, San Nicolás-Hernández, Desirée, Jiménez, Ignacio A, Lorenzo-Morales, Jacob, Piñero, José E, Bazzocchi, Isabel L

“…Leishmaniasis and Chagas are among the most significant neglected tropical diseases. Due to several drawbacks with the current chemotherapy, developing new…”
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Salvadoran Celastraceae Species as a Source of Antikinetoplastid Quinonemethide Triterpenoids by Núñez, Marvin J, Martínez, Morena L, Castillo, Ulises G, Flores, Karla Carolina, Menjívar, Jenny, López-Arencibia, Atteneri, Bethencourt-Estrella, Carlos J, Jiménez, Ignacio A, Piñero, José E, Lorenzo-Morales, Jacob, Bazzocchi, Isabel L

“…Chagas disease and leishmaniasis are among the most widespread neglected tropical diseases, and their current therapies have limited efficacy and several toxic…”
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Distinct sesquiterpene pyridine alkaloids from in Salvadoran and Peruvian Celastraceae species by Callies, Oliver, Núñez, Marvin J., Perestelo, Nayra R., Reyes, Carolina P., Torres-Romero, David, Jiménez, Ignacio A., Bazzocchi, Isabel L.

“…As part of a bioprospecting program aimed at the discovery of undescribed natural products from Salvadoran and Peruvian flora, the phytochemical investigations…”
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Screening of medicinal plants from El Salvador for anti-viral activity against Herpes simplex 1 by Franco-Espínola, José, Núñez, Marvin J, Sanabria-Ramírez, Y Mabel, Villar-Duarte, Carlos Fabio, Castillo, Ulises G, Cantero-González, Guadalupe, Florentín-Pavía, Marcos, Langjahr, Patricia, Sotelo Torres, Pablo Hernán

“…Herpes simplex virus 1 is one of the most prevalent pathogens worldwide. Resistant strains to current anti-viral treatment have been reported, requiring the…”
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Diels–Alder adducts from Celastraceae species by Bazzocchi, Isabel L., Núñez, Marvin J., Reyes, Carolina P.

“…Celastraceae species are a rich source of adducts whose biosynthesis has been hypothesized as involving a Diels–Alder reaction. The co-occurrence of these…”
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Bioactive diterpenoids from Celastraceae species by Bazzocchi, Isabel L., Núñez, Marvin J., Reyes, Carolina P.

“…Celastraceae species have a long tradition of use in folk medicine and agriculture. Intensive research into this family has resulted in the isolation of a…”
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Dihydro-β-agarofuran sesquiterpenes from celastraceae species as anti-tumour-promoting agents: Structure-activity relationship by Núñez, Marvin J., Jiménez, Ignacio A., Mendoza, Cristina R., Chavez-Sifontes, Marvin, Martinez, Morena L., Ichiishi, Eiichiro, Tokuda, Ryo, Tokuda, Harukuni, Bazzocchi, Isabel L.

“…Inhibition of tumour promotion in multistage chemical carcinogenesis is considered a promising strategy for cancer chemoprevention. In an ongoing investigation…”
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Studies of naturally occurring friedelane triterpenoids as insulin sensitizers in the treatment type 2 diabetes mellitus by Ardiles, Alejandro E., González-Rodríguez, Águeda, Núñez, Marvin J., Perestelo, Nayra R., Pardo, Virginia, Jiménez, Ignacio A., Valverde, Ángela M., Bazzocchi, Isabel L.

“…Nine fridelane triterpenes and twenty two known ones were isolated from Celastraceae species. Two compounds exhibited potent insulinomimetic effect on insulin…”
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Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2 by REYES, Carolina P, NUNEZ, Marvin J, JIMENEZ, Ignacio A, BUSSEROLLES, Jérome, ALCARAZ, Maria J, BAZZOCCHI, Isabel L

“…In the present study, we report that three new lupane triterpenes (1-3), in addition to 16 known ones (4-19), were isolated from the root bark of Maytenus…”
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Biological Evaluation, Structure−Activity Relationships, and Three-Dimensional Quantitative Structure−Activity Relationship Studies of Dihydro-β-agarofuran Sesquiterpenes as Modulators of P-Glycoprotein-Dependent Multidrug Resistance by Reyes, Carolina P, Muñoz-Martínez, Francisco, Torrecillas, Ivan R, Mendoza, Cristina R, Gamarro, Francisco, Bazzocchi, Isabel L, Núñez, Marvin J, Pardo, Leonardo, Castanys, Santiago, Campillo, Mercedes, Jiménez, Ignacio A

“…Multidrug resistance (MDR) is one of the main challenges in the chemotherapy of cancer, malaria, and other important diseases. Here, we report the inhibitory…”
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Uragogin and blepharodin, unprecedented hetero-Diels–Alder adducts from Celastraceae species by Núñez, Marvin J., Kennedy, María L., Jiménez, Ignacio A., Bazzocchi, Isabel L.

“…Uragogin and blepharodin were isolated from Crossopetalum uragoga and Maytenus magellanica, respectively. They represent the first examples of a…”
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ent-Rosane and abietane diterpenoids as cancer chemopreventive agents by Núñez, Marvin J., Reyes, Carolina P., Jiménez, Ignacio A., Hayashi, Hirotaka, Tokuda, Harukuni, Bazzocchi, Isabel L.

“…Two ent-rosane and an abietatriene diterpenoids have been isolated from species of the Celastraceae, along with five known compounds. The absolute…”
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Lupane Triterpenoids from Maytenus Species by Núñez, Marvin J, Reyes, Carolina P, Jiménez, Ignacio A, Moujir, Laila, Bazzocchi, Isabel L

“…Five new lupane triterpenes (1−5), in addition to 24 known ones, were isolated from Maytenus cuzcoina and M. chiapensis. Their structures were elucidated on…”
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Triterpenoids from Cassine xylocarpa and Celastrus vulcanicola (Celastraceae) by Núñez, Marvin J., Ardiles, Alejandro E., Martínez, Morena L., Torres-Romero, David, Jiménez, Ignacio A., Bazzocchi, Isabel L.

“…[Display omitted] ► Two new triterpenoids from two Salvadorean Celastraceae species. ► Xyloketal, first example of 3,25-epoxy-olean-12-ene from Celastraceae. ►…”
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