Search Results - "Núñez, Ángel"

Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43 by Maroto, Irene B., Costas-Insua, Carlos, Berthoux, Coralie, Moreno, Estefanía, Ruiz-Calvo, Andrea, Montero-Fernández, Carlos, Macías-Camero, Andrea, Martín, Ricardo, García-Font, Nuria, Sánchez-Prieto, José, Marsicano, Giovanni, Bellocchio, Luigi, Canela, Enric I., Casadó, Vicent, Galve-Roperh, Ismael, Núñez, Ángel, Fernández de Sevilla, David, Rodríguez-Crespo, Ignacio, Castillo, Pablo E., Guzmán, Manuel

“…The type-1 cannabinoid receptor (CB 1 R) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release, its…”
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Synthetic MRI improves radiomics‐based glioblastoma survival prediction by Moya‐Sáez, Elisa, Navarro‐González, Rafael, Cepeda, Santiago, Pérez‐Núñez, Ángel, Luis‐García, Rodrigo, Aja‐Fernández, Santiago, Alberola‐López, Carlos

“…Glioblastoma is an aggressive and fast‐growing brain tumor with poor prognosis. Predicting the expected survival of patients with glioblastoma is a key task…”
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Astrocytic IGF-IRs Induce Adenosine-Mediated Inhibitory Downregulation and Improve Sensory Discrimination by Noriega-Prieto, José Antonio, Maglio, Laura Eva, Zegarra-Valdivia, Jonathan A, Pignatelli, Jaime, Fernandez, Ana M, Martinez-Rachadell, Laura, Fernandes, Jansen, Núñez, Ángel, Araque, Alfonso, Torres-Alemán, Ignacio, Fernández de Sevilla, David

“…Insulin-like growth factor-I (IGF-I) signaling plays a key role in learning and memory processes. While the effects of IGF-I on neurons have been studied…”
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Tumor-Derived Pericytes Driven by EGFR Mutations Govern the Vascular and Immune Microenvironment of Gliomas by Segura-Collar, Berta, Garranzo-Asensio, María, Herranz, Beatriz, Hernández-SanMiguel, Esther, Cejalvo, Teresa, Casas, Bárbara S, Matheu, Ander, Pérez-Núñez, Ángel, Sepúlveda-Sánchez, Juan Manuel, Hernández-Laín, Aurelio, Palma, Verónica, Gargini, Ricardo, Sánchez-Gómez, Pilar

“…The extraordinary plasticity of glioma cells allows them to contribute to different cellular compartments in tumor vessels, reinforcing the vascular…”
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Sexual-biased necroinflammation is revealed as a predictor of bevacizumab benefit in glioblastoma by Hiller-Vallina, Sara, Mondejar-Ruescas, Lucia, Caamaño-Moreno, Marta, Cómitre-Mariano, Blanca, Alcivar-López, Denisse, Sepulveda, Juan M, Hernández-Laín, Aurelio, Pérez-Núñez, Ángel, Segura-Collar, Berta, Gargini, Ricardo

“…Abstract Background Glioblastoma (GBM) is a highly malignant brain tumor that affects men more often than women. In addition, the former shows a poorer…”
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Trotabresib, an oral potent bromodomain and extraterminal inhibitor, in patients with high-grade gliomas: A phase I, “window-of-opportunity” study by Moreno, Victor, Manuel Sepúlveda, Juan, Reardon, David A, Pérez-Núñez, Ángel, González León, Pedro, Hanna, Bishoy, Filvaroff, Ellen, Aronchik, Ida, Chang, Henry, Amoroso, Barbara, Zuraek, Marlene, Sanchez-Perez, Tania, Mendez, Cristina, Stephens, Daniel, Nikolova, Zariana, Vogelbaum, Michael A

“…Abstract Background The bromodomain and extraterminal protein (BET) inhibitor trotabresib has demonstrated antitumor activity in patients with advanced solid…”
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Anti-apoptotic, anti-oxidant, and anti-inflammatory effects of thalidomide on cerebral ischemia/reperfusion injury in rats by Palencia, Guadalupe, Medrano, Juan Ángel Núñez, Ortiz-Plata, Alma, Farfán, Dolores Jiménez, Sotelo, Julio, Sánchez, Aurora, Trejo-Solís, Cristina

“…Abstract Thalidomide has shown protective effects in different models of ischemia/reperfusion damage. To elucidate the mechanisms of such protection, this…”
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Association of Functional Polymorphisms of KIR3DL1/DS1 With Behçet's Disease by Castaño-Núñez, Ángel, Montes-Cano, Marco-Antonio, García-Lozano, José-Raúl, Ortego-Centeno, Norberto, García-Hernández, Francisco-José, Espinosa, Gerard, Graña-Gil, Genaro, Sánchez-Bursón, Juan, Juliá, María-Rosa, Solans, Roser, Blanco, Ricardo, Barnosi-Marín, Ana-Celia, Gómez de la Torre, Ricardo, Fanlo, Patricia, Rodríguez-Carballeira, Mónica, Rodríguez-Rodríguez, Luis, Camps, Teresa, Castañeda, Santos, Alegre-Sancho, Juan-Jose, Martín, Javier, González-Escribano, María-Francisca

“…Behçet's disease (BD) is an immune-mediated vasculitis related to imbalances between the innate and adaptive immune response. Infectious agents or…”
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Horizontes educativos ante el auge de la “nueva extrema derecha” en Europa: Un análisis documental by Neubauer, Adrián, Méndez-Núñez, Angel

“…Ante la irrupción de la “nueva extrema derecha” europea, y la consolidación de su representación parlamentaria tanto en instancias europeas como…”
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Immune Profiling of Gliomas Reveals a Connection with IDH1/2 Mutations, Tau Function and the Vascular Phenotype by Cejalvo, Teresa, Gargini, Ricardo, Segura-Collar, Berta, Mata-Martínez, Pablo, Herranz, Beatriz, Cantero, Diana, Ruano, Yolanda, García-Pérez, Daniel, Pérez-Núñez, Ángel, Ramos, Ana, Hernández-Laín, Aurelio, Martín-Soberón, María Cruz, Sánchez-Gómez, Pilar, Sepúlveda-Sánchez, Juan M.

“…Background: Gliomas remain refractory to all attempted treatments, including those using immune checkpoint inhibitors. The characterization of the tumor…”
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Hospitalizations realted to herpes zoster infection in the Canary Islands, Spain (2005-2014) by García-Rojas, Amós, Gil-Prieto, Ruth, Núñez-Gallo, Domingo Ángel, Matute-Cruz, Petra, Gil-de-Miguel, Angel

“…Herpes zoster is an important problem of public health especially among the elderly in Spain. A population-based retrospective epidemiological study to…”
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Modulation of Specific Sensory Cortical Areas by Segregated Basal Forebrain Cholinergic Neurons Demonstrated by Neuronal Tracing and Optogenetic Stimulation in Mice by Chaves-Coira, Irene, Barros-Zulaica, Natali, Rodrigo-Angulo, Margarita, Núñez, Ángel

“…Neocortical cholinergic activity plays a fundamental role in sensory processing and cognitive functions. Previous results have suggested a refined anatomical…”
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Idiopathic Subarachnoid Hemorrhage and Venous Drainage: Are They Related? by Alén, José F., Lagares, Alfonso, Campollo, Jorge, Ballenilla, Federico, Kaen, Ariel, Núñez, Ángel P., Lobato, Ramiro D.

“…Abstract OBJECTIVE In the past, several possible explanations for idiopathic subarachnoid hemorrhage (ISAH) have been proposed; however, neuroimaging studies…”
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Medical outcomes study social support survey (MOS-SSS) in patients with chronic disease: A psychometric assessment by Merino-Soto, Cesar, Núñez Benítez, Miguel Ángel, Domínguez-Guedea, Miriam Teresa, Toledano-Toledano, Filiberto, Moral de la Rubia, José, Astudillo-García, Claudia I, Rivera-Rivera, Leonor, Leyva-López, Ahidée, Angulo-Ramos, Marisol, Flores Laguna, Omar Arodi, Hernández-Salinas, Gregorio, Rodríguez Castro, Jorge Homero, González Peña, Omar Israel, Garduño Espinosa, Juan

“…Currently, information on the psychometric properties of the Medical outcomes study-social support survey (MOS-SSS) for patients with chronic disease in…”
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The September 2019 floods in Spain: An example of the utility of satellite data for the analysis of extreme hydrometeorological events by Tapiador, Francisco J., Marcos, Cecilia, Sancho, Juan Manuel, Santos, Carlos, Núñez, José Ángel, Navarro, Andrés, Kummerow, Chris, Adler, Robert F.

“…Major floods in Spain in September 9–13, 2019 resulted in seven casualties and massive losses to agriculture, property and infrastructure. This paper…”
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Corrigendum: Bidirectional Hebbian Plasticity Induced by Low-Frequency Stimulation in Basal Dendrites of Rat Barrel Cortex Layer 5 Pyramidal Neurons by Díez-García, Andrea, Barros-Zulaica, Natali, Núñez, Ángel, Buño, Washington, Fernández de Sevilla, David

“…[This corrects the article on p. 8 in vol. 11, PMID: 28203145.]…”
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Impact on the Quality of Life and Physiological Parameters in Patients with Diabetes Mellitus by Reina-Bueno, María, Palomo-Toucedo, Inmaculada C., Medina-Núñez, Manuel Ángel, Munuera-Martínez, Pedro V., Castro-Méndez, Aurora, Vázquez-Bautista, María del Carmen

“…The co-existence of complications and diabetes mellitus is related to a worsening in quality of life compared to not presenting comorbidities. This study aimed…”
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Bidirectional Hebbian Plasticity Induced by Low-Frequency Stimulation in Basal Dendrites of Rat Barrel Cortex Layer 5 Pyramidal Neurons by Díez-García, Andrea, Barros-Zulaica, Natali, Núñez, Ángel, Buño, Washington, Fernández de Sevilla, David

“…According to Hebb's original hypothesis (Hebb, 1949), synapses are reinforced when presynaptic activity triggers postsynaptic firing, resulting in long-term…”
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Horizontal visibility graphs generated by type-I intermittency by Núñez, Ángel M, Luque, Bartolo, Lacasa, Lucas, Gómez, Jose Patricio, Robledo, Alberto

“…The type-I intermittency route to (or out of) chaos is investigated within the horizontal visibility (HV) graph theory. For that purpose, we address the…”
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A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis by Zhu, Lucía, Retana, Diana, García‐Gómez, Pedro, Álvaro‐Espinosa, Laura, Priego, Neibla, Masmudi‐Martín, Mariam, Yebra, Natalia, Miarka, Lauritz, Hernández‐Encinas, Elena, Blanco‐Aparicio, Carmen, Martínez, Sonia, Sobrino, Cecilia, Ajenjo, Nuria, Artiga, Maria‐Jesus, Ortega‐Paino, Eva, Torres‐Ruiz, Raúl, Rodríguez‐Perales, Sandra, Soffietti, Riccardo, Bertero, Luca, Cassoni, Paola, Weiss, Tobias, Muñoz, Javier, Sepúlveda, Juan Manuel, González‐León, Pedro, Jiménez‐Roldán, Luis, Moreno, Luis Miguel, Esteban, Olga, Pérez‐Núñez, Ángel, Hernández‐Laín, Aurelio, Toldos, Oscar, Ruano, Yolanda, Alcázar, Lucía, Blasco, Guillermo, Fernández‐Alén, José, Caleiras, Eduardo, Lafarga, Miguel, Megías, Diego, Graña‐Castro, Osvaldo, Nör, Carolina, Taylor, Michael D, Young, Leonie S, Varešlija, Damir, Cosgrove, Nicola, Couch, Fergus J, Cussó, Lorena, Desco, Manuel, Mouron, Silvana, Quintela‐Fandino, Miguel, Weller, Michael, Pastor, Joaquín, Valiente, Manuel, de la Lama‐Zaragoza, Adolfo, Calero‐Felix, Lourdes, Fiaño‐Valverde, Concepcion, Delgado‐López, Pedro David, Montalvo‐Afonso, Antonio, Pascual‐Llorente, Mar, Díaz‐Piqueras, Ángela, Nam‐Cha, SH, Barrena López, Cristina, Plans Ahicart, Gerard, Martínez‐Saez, Elena, Ramón y Cajal, Santiago, Nicolás, Pilar

“…We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing…”
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