Risk for Severe COVID-19 Outcomes among Persons with Intellectual Disabilities, the Netherlands

The COVID-19 pandemic has disproportionately affected persons in long-term care, who often experience health disparities. To delineate the COVID-19 disease burden among persons with intellectual disabilities, we prospectively collected data from 36 care facilities for 3 pandemic waves during March 2...

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Bibliographic Details
Published in:	Emerging infectious diseases Vol. 29; no. 1; pp. 118 - 126
Main Authors:	Koks-Leensen, Monique C J, Schalk, Bianca W M, Bakker-van Gijssel, Esther J, Timen, Aura, Nägele, Masha E, van den Bemd, Milou, Leusink, Geraline L, Cuypers, Maarten, Naaldenberg, Jenneken
Format:	Journal Article
Language:	English
Published:	United States U.S. National Center for Infectious Diseases 01-01-2023 Centers for Disease Control and Prevention
Subjects:	Comorbidity coronavirus disease COVID-19 COVID-19 - epidemiology Developmentally disabled Disabilities Down syndrome Epidemics Fatalities Group homes Health aspects Health disparities Health policy Hospitals Humans Illnesses Infections Intellectual disabilities Intellectual Disability - epidemiology Long term health care Long-term care Long-term care of the sick Medical policy Medical research Medicine, Experimental Mortality Netherlands Netherlands - epidemiology Oxygen therapy Pandemics Patients Population Public health Regression analysis respiratory infections Risk factors Risk for Severe COVID-19 Outcomes among Persons with Intellectual Disabilities, the Netherlands SARS SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Statistics Netherlands viruses data register long-term care SARS coronavirus zoonoses respiratory infections the Netherlands COVID-19 SARS-CoV-2 case fatality severe acute respiratory syndrome coronavirus 2 coronavirus disease intellectual disability
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Summary:	The COVID-19 pandemic has disproportionately affected persons in long-term care, who often experience health disparities. To delineate the COVID-19 disease burden among persons with intellectual disabilities, we prospectively collected data from 36 care facilities for 3 pandemic waves during March 2020-May 2021. We included outcomes for 2,586 clients with PCR-confirmed SARS-CoV-2 infection, among whom 161 had severe illness and 99 died. During the first 2 pandemic waves, infection among persons with intellectual disabilities reflected patterns observed in the general population, but case-fatality rates for persons with intellectual disabilities were 3.5 times higher and were elevated among those >40 years of age. Severe outcomes were associated with older age, having Down syndrome, and having >1 concurrent condition. Our study highlights the disproportionate COVID-19 disease burden among persons with intellectual disabilities and the need for disability-inclusive research and policymaking to inform disease surveillance and public health policies for this population.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2901.221346