Search Results - "Nájera, José L"

The poxvirus vectors MVA and NYVAC as gene delivery systems for vaccination against infectious diseases and cancer by Gómez, Carmen E, Nájera, José L, Krupa, Magdalena, Esteban, Mariano

“…Recombinants based on poxviruses have been used extensively as gene delivery systems to study many biological functions of foreign genes and as vaccines…”
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Multimeric soluble CD40 ligand (sCD40L) efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus vectors MVA and NYVAC expressing HIV antigens by Gómez, Carmen E, Nájera, José L, Sánchez, Raquel, Jiménez, Victoria, Esteban, Mariano

“…Abstract The attenuated poxvirus vectors MVA and NYVAC are now in clinical trials against HIV/AIDS. Due to the vectors restricted replication capacity in human…”
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Differential CD4+ versus CD8+ T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates by MOOIJ, Petra, BALLA-JHAGJHOORSINGH, Sunita S, GOMEZ, Carmen E, NAJERA, José L, JIMENEZ, Victoria, ESTEBAN, Mariano, HEENEY, Jonathan L, KOOPMAN, Gerrit, BEENHAKKER, Niels, VAN HAAFTEN, Patricia, BAAK, Ilona, NIEUWENHUIS, Ivonne G, KONDOVA, Ivanela, WAGNER, Ralf, WOLF, Hans

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Expression of the E3L Gene of Vaccinia Virus in Transgenic Mice Decreases Host Resistance to Vaccinia Virus and Leishmania major Infections by DOMINGO-GIL, Elena, PEREZ-JIMENEZ, Eva, VENTOSO, Ivan, NAJERA, José L, ESTEBAN, Mariano

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T-cell immune responses against Env from CRF12_BF and subtype B HIV-1 show high clade-specificity that can be overridden by multiclade immunizations by Mónaco, Daniela C, Rodríguez, Ana M, Pascutti, María F, Carobene, Mauricio, Falivene, Juliana, Gómez, Alejandro, Maeto, Cynthia, Turk, Gabriela, Nájera, José L, Esteban, Mariano, Gherardi, M Magdalena

“…The extreme genetic diversity of the human immunodeficiency virus type 1 (HIV-1) poses a daunting challenge to the generation of an effective AIDS vaccine. In…”
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MVA and NYVAC as vaccines against emergent infectious diseases and cancer by Gómez, Carmen E, Nájera, José L, Krupa, Magdalena, Perdiguero, Beatriz, Esteban, Mariano

“…Recombinants based on poxviruses have been used extensively as gene delivery systems to study many biological functions of foreign genes and as vaccines…”
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Selective Induction of Host Genes by MVA-B, a Candidate Vaccine against HIV/AIDS by GUERRA, Susana, MANUEL GONZALEZ, José, ESTEBAN, Mariano, CLIMENT, Núria, REYBURN, Hugh, LOPEZ-FERNANDEZ, Luis A, NAJERA, José L, GOMEZ, Carmen E, GARCIA, Felipe, GATELL, José M, GALLART, Teresa

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Immunization with recombinant DNA and modified vaccinia virus Ankara (MVA) vectors delivering PSCA and STEAP1 antigens inhibits prostate cancer progression by Krupa, Magdalena, Canamero, Marta, Gomez, Carmen E, Najera, Jose L, Gil, Jesus, Esteban, Mariano

“…Abstract Despite recent advances in early detection and improvement of conventional therapies, there is an urgent need for development of additional approaches…”
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Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pot and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02) by Garcia, F, Lopez, Bernaldo de Quiros JC, Gomez, CE, Perdiguero, B, Najera, JL, Jimenez, V, Garcia-Arriaza, J, Guardo, AC, Perez, I, Diaz-Brito, V

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Differential CD4 super(+) versus CD8 super(+) T-Cell Responses Elicited by Different Poxvirus-Based Human Immunodeficiency Virus Type 1 Vaccine Candidates Provide Comparable Efficacies in Primates by Mooij, Petra, Balla-Jhagjhoorsingh, Sunita S, Koopman, Gerrit, Beenhakker, Niels, van Haaften, Patricia, Baak, Ilona, Nieuwenhuis, Ivonne G, Kondova, Ivanela, Wagner, Ralf, Wolf, Hans, Gomez, Carmen E, Najera, Jose L, Jimenez, Victoria, Esteban, Mariano, Heeney, Jonathan L

“…Poxvirus vectors have proven to be highly effective for boosting immune responses in diverse vaccine settings. Recent reports reveal marked differences in the…”
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