Search Results - "NÖSSNER, G"

D-21266, a new heterocyclic alkylphospholipid with antitumour activity by Hilgard, P., Klenner, T., Stekar, J., Nössner, G., Kutscher, B., Engel, J.

“…The aim of this study was to determine the antitumour effects of D-21266 in a rodent tumour model. Hexadecylphosphocholine (INN: Miltefosine) represents the…”
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Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid, D-20133 by STEKAR, J, HILGARD, P, VOEGELI, R, MAURER, H. R, ENGEL, J, KUTSCHER, B, NÖSSNER, G, SCHUMACHER, W

“…Octadecyl-[2-(N-methylpiperidinio)ethyl]-phosphate (OMPEP, D-20133), a heterocyclic analogue of hexadecylphosphocholine (MIL), has been synthesized in an…”
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Early stage monitoring of miltefosine induced apoptosis in KB cells by multinuclear NMR spectroscopy by Engelmann, J, Henke, J, Willker, W, Kutscher, B, Nössner, G, Engel, J, Leibfritz, D

“…Synthetic ether lipids, like miltefosine (hexadecylphosphocholine), an alkylphosphocholine, are antineoplastic agents in vitro and in vivo. Their mode of…”
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Alkylphosphate esters as inhibitors of phospholipase D by Dittrich, N, Nössner, G, Kutscher, B, Ulbrich-Hofmann, R

“…Alkylphosphate esters were shown to be potent inhibitors of phospholipase D. Using phosphatidyl choline/sodium dodecylsulfate (2:1) as substrate, IC50 values…”
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Changes of intracellular calcium, fatty acids and phospholipids during miltefosine-induced apoptosis monitored by fluorescence- and 13C NMR-spectroscopy by Henke, J, Engelmann, J, Kutscher, B, Nssner, G, Engel, J, Voegeli, R, Leibfritz, D

“…The alkylphosphocholine Miltefosine (hexadecylphosphocholine, HePC) induces apoptosis in human epithelial KB cells, whereas no such effect can be observed in a…”
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Morphiceptin analogs containing 2-aminocyclopentane carboxylic acid as a peptidomimetic for proline by Mierke, D F, Nössner, G, Schiller, P W, Goodman, M

“…As part of a program to study the structure-activity relationship of peptide opioids we report the synthesis, conformational characterization and biological…”
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