Search Results - "N'ait ousidi, Abdellah"
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Electrochemical and theoretical studies of some monoterpenic thiazolidinones as corrosion inhibitors for steel in acidic media
Published in Journal of adhesion science and technology (03-07-2021)“…This work deals with the study of the inhibition activity of three thiazolidinones (prepared from monoterpenic ketones) on the deterioration of S300 steel in…”
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Investigating novel thiazolyl-indazole derivatives as scaffolds for SARS-CoV-2 MPro inhibitors
Published in European journal of medicinal chemistry reports (01-04-2022)“…COVID-19 is a global pandemic caused by infection with the SARS-CoV-2 virus. Remdesivir, a SARS-CoV-2 RNA polymerase inhibitor, is the only drug to have…”
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3
Cytotoxic and apoptotic effects of some (R)-carvone-isoxazoline derivatives on human fibrosarcoma and carcinoma cells: experimental evaluation for cytotoxicity, molecular docking and molecular dynamics studies
Published in Journal of biomolecular structure & dynamics (24-03-2023)“…This study aimed to analyze the cytotoxic and apoptotic effects of isoxazoline derivatives with monoterpene scaffold 9a-e in HT-1080 fibrosarcoma, MCF-7, and…”
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4
Convenient route to benzo[1,2,3]selenadiazole–isoxazole hybrids and evaluation of their in vitro cytotoxicity
Published in Chemical papers (01-05-2022)“…A series of novel benzo[1,2,3]selenadiazole–isoxazole hybrid compounds were designed and synthesized from natural ( R )-carvone. These derivatives were…”
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5
New polysubstituted monoterpenic thiazolidinones: synthesis, spectroscopic and crystal structure studies
Published in Acta crystallographica. Section C, Crystal structure communications (01-12-2018)“…The synthesis of three new polysubstituted monoterpenic thiazolidin‐4‐ones, namely…”
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Crystal structure of dimethyl 2-((2 Z ,5 Z )-5-(2-methoxy-2-oxoethylidene)-2-{( E )-[2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enylidene]hydrazinylidene}-4-oxothiazolidin-3-yl)fumarate
Published in Acta crystallographica. Section E, Crystallographic communications (01-02-2017)“…The crystal structure and the conformation of the title compound, C 22 H 27 N 3 O 7 S, were determined from the synthetic pathway and by X-ray analysis. This…”
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Crystal structure of 2-[(3a S ,6 R )-3,3,6-trimethyl-3,3a,4,5,6,7-hexahydro-2 H -indazol-2-yl]thiazol-4(5 H )-one
Published in Acta crystallographica. Section E, Crystallographic communications (01-03-2016)“…The title compound, C 13 H 19 N 3 OS, is a new thiazolidin-4-one derivative prepared and isolated as the pure (3a S ,6 R )-diastereisomer from ( R…”
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8
2-isopropyl-4-methoxy-5-methylphenol-hydrazone derivatives : Synthesis, characterization, and in-silico assessment of EGFR and Bcl2 inhibitory activity
Published in Journal of molecular structure (15-02-2025)“…•A series of natural bioactive hydrazone hybrids 10a-e were synthesized.•Synthetic products are characterized by NMR and HRMS.•Molecular docking and dynamic…”
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9
Crystal structure of dimethyl 2-((2 Z ,5 Z )-5-(2-meth-oxy-2-oxo-ethyl-idene)-2-{( E )-[2-methyl-5-(prop-1-en-2-yl)cyclo-hex-2-enyl-idene]hydrazinyl-idene}-4-oxo-thia-zolidin-3-yl)fumarate
Published in Acta crystallographica. Section E, Crystallographic communications (01-02-2017)“…The crystal structure and the conformation of the title compound, C H N O S, were determined from the synthetic pathway and by X-ray analysis. This compound is…”
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10
Crystal structure of 2-[(3aS,6R)-3,3,6-trimethyl-3,3a,4,5,6,7-hexa-hydro-2H-indazol-2-yl]thia-zol-4(5H)-one
Published in Acta crystallographica. Section E, Crystallographic communications (01-03-2016)“…The title compound, C13H19N3OS, is a new thia-zolidin-4-one derivative prepared and isolated as the pure (3aS,6R)-diastereisomer from (R)-thio-semicarbazone…”
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11
Investigating novel thiazolyl-indazole derivatives as scaffolds for SARS-CoV-2 M Pro inhibitors
Published in European journal of medicinal chemistry reports (01-04-2022)“…COVID-19 is a global pandemic caused by infection with the SARS-CoV-2 virus. Remdesivir, a SARS-CoV-2 RNA polymerase inhibitor, is the only drug to have…”
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12
Design, Synthesis, Cytotoxic Effect Evaluation and Molecular Docking of (R)‐Camphor‐Based Thiazolidinone‐Isoxazole and Thiazolidinone‐1,2,3‐triazole Hybrids
Published in ChemistrySelect (Weinheim) (09-01-2023)“…A variety of hybrid compounds, combining a camphor thiazolidinone skeleton with either 1,2,3‐triazole or isoxazole nucleus, have been synthesized from natural…”
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(3a R ,6 R )-3,3,6-Trimethyl-3,3a,4,5,6,7-hexahydro-2 H -indazole-2-carbothioamide
Published in IUCrData (28-04-2016)“…The title compound, C 11 H 19 N 3 S, was prepared by the reaction of ( R )-pulegone with thiosemicarbazide in acidic medium, using ethanol as solvent. The…”
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14
(3aR,6R)-3,3,6-Trimethyl-3,3a,4,5,6,7-hexahydro-2H-indazole-2-carbothioamide
Published in IUCrData (01-04-2016)“…The title compound, C11H19N3S, was prepared by the reaction of (R)-pulegone with thiosemicarbazide in acidic medium, using ethanol as solvent. The molecule is…”
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