Search Results - "N'Guyen, Lia"

PLZF limits enhancer activity during hematopoietic progenitor aging by Poplineau, Mathilde, Vernerey, Julien, Platet, Nadine, N'guyen, Lia, Hérault, Léonard, Esposito, Michela, Saurin, Andrew J, Guilouf, Christel, Iwama, Atsushi, Duprez, Estelle

“…Abstract PLZF (promyelocytic leukemia zinc finger) is a transcription factor acting as a global regulator of hematopoietic commitment. PLZF displays an…”
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Nucleosome eviction in mitosis assists condensin loading and chromosome condensation by Toselli-Mollereau, Esther, Robellet, Xavier, Fauque, Lydia, Lemaire, Sébastien, Schiklenk, Christoph, Klein, Carlo, Hocquet, Clémence, Legros, Pénélope, N'Guyen, Lia, Mouillard, Léo, Chautard, Emilie, Auboeuf, Didier, Haering, Christian H, Bernard, Pascal

“…Condensins associate with DNA and shape mitotic chromosomes. Condensins are enriched nearby highly expressed genes during mitosis, but how this binding is…”
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Epigenetic down-regulation of the HIST1 locus predicts better prognosis in acute myeloid leukemia with NPM1 mutation by Garciaz, Sylvain, N'guyen Dasi, Lia, Finetti, Pascal, Chevalier, Christine, Vernerey, Julien, Poplineau, Mathilde, Platet, Nadine, Audebert, Stéphane, Pophillat, Matthieu, Camoin, Luc, Bertucci, François, Calmels, Boris, Récher, Christian, Birnbaum, Daniel, Chabannon, Christian, Vey, Norbert, Duprez, Estelle

“…The epigenetic machinery is frequently altered in acute myeloid leukemia. Focusing on cytogenetically normal (CN) AML, we previously described an abnormal…”
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Noncanonical EZH2 drives retinoic acid resistance of variant acute promyelocytic leukemias by Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, N’Guyen, Lia, Koide, Shuhei, Nakajima-Takagi, Yaeko, Kuribayashi, Wakako, Carbuccia, Nadine, Haboub, Loreen, Vernerey, Julien, Oshima, Motohiko, Birnbaum, Daniel, Iwama, Atsushi, Duprez, Estelle

“…•Single cell multiomics in PLZF-RARA leukemic cells resolves the retinoic acid resistance network.•Targeting pan-EZH2 activities (canonical/noncanonical)…”
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Polo‐like‐kinase 1 is a proviral host factor for hepatitis B virus replication by Diab, Ahmed, Foca, Adrien, Fusil, Floriane, Lahlali, Thomas, Jalaguier, Pascal, Amirache, Fouzia, N'Guyen, Lia, Isorce, Nathalie, Cosset, François‐Loïc, Zoulim, Fabien, Andrisani, Ourania, Durantel, David

“…Chronic hepatitis B virus (HBV) infection is a major risk factor for hepatocellular carcinoma (HCC) and current treatments for chronic hepatitis B and HCC are…”
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Regulation of the positive transcriptional effect of PLZF through a non-canonical EZH2 activity by Koubi, Myriam, Poplineau, Mathilde, Vernerey, Julien, N'Guyen, Lia, Tiberi, Guillaume, Garciaz, Sylvain, El-Kaoutari, Abdessamad, Maqbool, Muhammad A, Andrau, Jean-Christophe, Guillouf, Christel, Saurin, Andrew J, Duprez, Estelle

“…Abstract The transcription factor PLZF (promyelocytic leukemia zinc finger protein) acts as an epigenetic regulator balancing self-renewal and differentiation…”
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3014 – NON-CANONICAL EZH2 DRIVES RETINOIC ACID RESISTANCE OF VARIANT ACUTE PROMYELOCYTIC LEUKEMIAS by Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, Koide, Shuhei, N'guyen, Lia, Iwama, Atsushi, Duprez, Estelle

“…Cancer cell heterogeneity is a major driver of therapy resistance. To characterize resistant cells and their vulnerabilities, we studied the PLZF-RARA variant…”
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3153 – NON-CANONICAL EZH2 DRIVES RESISTANCE IN ACUTE MYELOID LEUKEMIAS by Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, N'Guyen, Lia, Koide, Shuhei, Nakajima-Takagi, Yoko, Haboub, Loreen, Vernerey, Julien, Sarry, Jean-Emmanuel, Iwama, Atsushi, Duprez, Estelle

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Single Cell Analyses Reveal a Non-Canonical EZH2 Activity As a Main Driver of Retinoic Acid Resistance in PLZF/Rara Leukemia by Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, Koide, Shuhei, Kuribayashi, Wakako, Carbuccia, Nadine, N'Guyen, Lia, Vernerey, Julien, Oshima, Motohiko, Birnbaum, Daniel, Lachaud, Christophe, Iwama, Atsushi, Duprez, Estelle

“…Resistance to treatment is due to the heterogeneity of the tumor which contains a subset of cancer cells that escape treatment and are responsible for the…”
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New Insights into PLZF/Rara Mechanism during APL Onset: EZH2 on the Road by Poplineau, Mathilde, Platet, Nadine, N'Guyen, Lia, Koide, Shuhei, Vernerey, Julien, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Iwama, Atsushi, Duprez, Estelle

“…INTRODUCTION Inappropriate recruitment of functional Polycomb-Group proteins (PcG) may trigger epigenetic unbalance at very specific genomic loci that…”
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3115 – INTEGRATIVE MULTI-OMICS ANALYSIS FOR UNDERSTANDING ACUTE PROMYELOCYTIC LEUKEMIA RESISTANCE: EZH2 ON THE ROAD by Poplineau, Mathilde, Hérault, Léonard, Mazuel, Adrien, Platet, Nadine, Koide, Shuhei, Kuribayashi, Wakako, Carbuccia, Nadine, N'Guyen, Lia, Vernerey, Julien, Oshima, Motohiko, Birnbaum, Daniel, Lachaud, Christophe, Iwama, Atsushi, Duprez, Estelle

“…Oncogenic chimeric proteins play important role in the initiation and development of Acute Myeloid Leukemia (AML) and influence the response to therapeutics…”
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Non-canonical EZH2 drives retinoic acid resistance of variant acute promyelocytic leukemias by Poplineau, Mathilde, Platet, Nadine, Mazuel, Adrien, Hérault, Léonard, N’guyen, Lia, Koide, Shuhei, Nakajima-Takagi, Yaeko, Kuribayashi, Wakako, Carbuccia, Nadine, Haboub, Loreen, Vernerey, Julien, Oshima, Motohiko, Birnbaum, Daniel, Iwama, Atsushi, Duprez, Estelle

“…Cancer cell heterogeneity is a major driver of therapy resistance. To characterize resistant cells and their vulnerabilities, we studied the PLZF-RARA variant…”
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