Search Results - "Mzava, Omary"
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Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
Published in Nature communications (11-06-2024)“…Spaceflight induces an immune response in astronauts. To better characterize this effect, we generated single-cell, multi-ome, cell-free RNA (cfRNA),…”
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A quantitative comparison of urine centrifugation and filtration for the isolation and analysis of urinary nucleic acid biomarkers
Published in Scientific reports (13-05-2024)“…Urine is a rich source of nucleic acid biomarkers including cell-free DNA (cfDNA) and RNA for monitoring the health of kidney allografts. In this study, we…”
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Measurement Biases Distort Cell-Free DNA Fragmentation Profiles and Define the Sensitivity of Metagenomic Cell-Free DNA Sequencing Assays
Published in Clinical chemistry (Baltimore, Md.) (30-12-2021)“…Abstract Background Metagenomic sequencing of microbial cell-free DNA (cfDNA) in blood and urine is increasingly used as a tool for unbiased infection…”
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Spatiotemporal expression and control of haemoglobin in space
Published in Nature communications (11-06-2024)“…It is now widely recognised that the environment in space activates a diverse set of genes involved in regulating fundamental cellular pathways. This includes…”
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Metagenomic DNA sequencing to quantify Mycobacterium tuberculosis DNA and diagnose tuberculosis
Published in Scientific reports (10-10-2022)“…Tuberculosis (TB) remains a significant cause of mortality worldwide. Metagenomic next-generation sequencing has the potential to reveal biomarkers of active…”
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A metagenomic DNA sequencing assay that is robust against environmental DNA contamination
Published in Nature communications (21-07-2022)“…Metagenomic DNA sequencing is a powerful tool to characterize microbial communities but is sensitive to environmental DNA contamination, in particular when…”
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Magnetic micro/nanoparticle flocculation-based signal amplification for biosensing
Published in International journal of nanomedicine (01-01-2016)“…We report a time and cost efficient signal amplification method for biosensors employing magnetic particles. In this method, magnetic particles in an applied…”
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Detection of Proteins Using Nano Magnetic Particle Accumulation-Based Signal Amplification
Published in Applied sciences (2016)“…We report a biosensing method based on magnetic particles where coated magnetic particles are used for immunomagnetic separation, and uncoated magnetic…”
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The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Published in Nature (London) (29-08-2024)“…Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming…”
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Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight
Published in Precision clinical medicine (01-03-2024)“…Abstract Background The Inspiration4 (I4) mission, the first all-civilian orbital flight mission, investigated the physiological effects of short-duration…”
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