Search Results - "Mysore, Veena S"
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Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
Published in Molecular cancer (07-02-2011)“…Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant, commonly known as turmeric. Curcumin has been used extensively in Ayurvedic…”
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Key Players of the Immunosuppressive Tumor Microenvironment and Emerging Therapeutic Strategies
Published in Frontiers in cell and developmental biology (08-03-2022)“…The tumor microenvironment (TME) is a complex, dynamic battlefield for both immune cells and tumor cells. The advent of the immune checkpoint inhibitors (ICI)…”
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Hyperactivated JNK Is a Therapeutic Target in pVHL-Deficient Renal Cell Carcinoma
Published in Cancer research (Chicago, Ill.) (15-02-2013)“…Clear cell renal cell carcinomas (RCC), the major histologic subtype of RCC accounting for more than 80% of cases, are typified by biallelic inactivation of…”
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A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity
Published in Molecular cancer research (01-03-2016)“…Multiple myeloma is incurable and invariably becomes resistant to chemotherapy. Although the mechanisms remain unclear, hypoxic conditions in the bone marrow…”
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Enhanced CTLA‐4 blockade anti‐tumor immunity with APG‐157 combination in a murine head and neck cancer
Published in Cancer medicine (Malden, MA) (01-05-2024)“…Background A phase I clinical study for patients with locally advanced H&N cancer with a new class of botanical drug APG‐157 provided hints of potential…”
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Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma
Published in Clinical cancer research (01-10-2005)“…Purpose: The purpose of this study was to determine whether curcumin would trigger cell death in the head and neck squamous cell carcinoma (HNSCC) cell lines…”
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The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer
Published in PloS one (12-06-2009)“…Malignant Pleural Effusions (MPE) may be useful as a model to study hierarchical progression of cancer and/or intratumoral heterogeneity. To strengthen the…”
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The CD44(high) tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression
Published in PloS one (2013)“…Cellular heterogeneity is an integral part of cancer development and progression. Progression can be associated with emergence of cells that exhibit high…”
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Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer
Published in The Journal of biological chemistry (11-12-2020)“…We have observed overexpression of PACS-1, a cytosolic sorting protein in primary cervical tumors. Absence of exonic mutations and overexpression at the RNA…”
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Liposome-Encapsulated Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma In vitro and in Xenografts through the Inhibition of Nuclear Factor κB by an AKT-Independent Pathway
Published in Clinical cancer research (01-10-2008)“…Purpose: The purpose of this study was to determine whether a liposomal formulation of curcumin would suppress the growth of head and neck squamous cell…”
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Curcumin Treatment Suppresses IKKβ Kinase Activity of Salivary Cells of Patients with Head and Neck Cancer: A Pilot Study
Published in Clinical cancer research (15-09-2011)“…To determine whether curcumin would inhibit IκB kinase β (IKKβ) kinase activity and suppress expression of proinflammatory cytokines in head and neck squamous…”
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Adipose-Derived Mesenchymal Stromal Cells Persist in Tissue-Engineered Vocal Fold Replacement in Rabbits
Published in Annals of otology, rhinology & laryngology (01-12-2018)“…Objectives: Cell therapies using mesenchymal stromal cells (MSCs) have been proposed as a promising new tool for the treatment of vocal fold scarring. However,…”
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Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma via inhibition of IKKβ protein of the NFκB pathway
Published in Molecular cancer therapeutics (01-10-2010)“…Previous experiments have shown that curcumin or cisplatin treatment suppresses growth of head and neck squamous cell carcinoma (HNSCC). To study the potential…”
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Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-κB
Published in Molecular and cellular biology (01-06-2016)“…We and others have shown that the cystatin E/M gene is inactivated in primary human tumors, pointing to its role as a tumor suppressor gene. However, the…”
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Cancer stem cells, microRNAs, and therapeutic strategies including natural products
Published in Cancer and metastasis reviews (01-12-2012)“…Embryonic stem cells divide continuously and differentiate into organs through the expression of specific transcription factors at specific time periods…”
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p16 Protein and Gigaxonin Are Associated with the Ubiquitination of NFκB in Cisplatin-induced Senescence of Cancer Cells
Published in The Journal of biological chemistry (12-12-2014)“…The molecular mechanism of p16-mediated senescence in cisplatin-treated cancer cells is not fully understood. Here we show that cisplatin treatment of head and…”
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Correction: The CD44high Tumorigenic Subsets in Lung Cancer Biospecimens Are Enriched for Low miR-34a Expression
Published in PloS one (01-09-2013)“…[This corrects the article on p. e73195 in vol. 8.]…”
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Gigaxonin Suppresses Epithelial-to-Mesenchymal Transition of Human Cancer Through Downregulation of Snail
Published in Cancer research communications (08-03-2024)“…Gigaxonin is an E3 ubiquitin ligase that plays a role in cytoskeletal stability. Its role in cancer is not yet clearly understood. Our previous studies of head…”
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CAR mediates efficient tumor engraftment of mesenchymal type lung cancer cells
Published in Laboratory investigation (01-08-2009)“…The coxsackie-adenovirus receptor (CAR) is a developmentally regulated intercellular adhesion molecule that was previously observed to be required for…”
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Correction: The CD44 high Tumorigenic Subsets in Lung Cancer Biospecimens Are Enriched for Low miR-34a Expression
Published in PloS one (30-09-2013)“…[This corrects the article on p. e73195 in vol. 8.]…”
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