Search Results - "Myrand, SP"

Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First- and Third-generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations by Myrand, SP, Sekiguchi, K, Man, MZ, Lin, X, Tzeng, R‐Y, Teng, C‐H, Hee, B, Garrett, M, Kikkawa, H, Lin, C‐Y, Eddy, SM, Dostalik, J, Mount, J, Azuma, J, Fujio, Y, Jang, I‐J, Shin, S‐G, Bleavins, MR, Williams, JA, Paulauskis, JD, Wilner, KD

“…Application of foreign clinical data across geographic regions can accelerate drug development. Drug disposition can be variable, and identification of factors…”
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An association study of 43 SNPs in 16 candidate genes with atorvastatin response by Thompson, J F, Man, M, Johnson, K J, Wood, L S, Lira, M E, Lloyd, D B, Banerjee, P, Milos, P M, Myrand, S P, Paulauskis, J, Milad, M A, Sasiela, W J

“…Variation in individual response to statin therapy has been widely studied for a potential genetic component. Multiple genes have been identified as potential…”
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PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase by Reiners, Jr, J J, Lee, J Y, Clift, R E, Dudley, D T, Myrand, S P

“…PD98059 [2-(2'-amino-3'-methoxyphenyl)-oxanaphthalen-4-one] is a flavonoid and a potent inhibitor of mitogen-activated protein kinase kinase (MEK)…”
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Distribution of mutations in the human xeroderma pigmentosum group A gene and their relationships to the functional regions of the DNA damage recognition protein by States, JC, McDuffie, ER, Myrand, SP, McDowell, M, Cleaver, JE

“…A series of xeroderma pigmentosum group A cell lines from 19 patients and cell lines from 13 other family members were examined for XPA mutations to find…”
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High throughput genotyping for the detection of a single nucleotide polymorphism in NAD(P)H quinone oxidoreductase (DT diaphorase) using TaqMan probes by Shi, M M, Myrand, S P, Bleavins, M R, de la Iglesia, F A

“…AIMS: The two electron reduction of quinones to hydroquinones by NAD(P)H quinone oxidoreductase (NQO1) plays an important role in both activation and…”
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Differential induction of Cyp1a1, Cyp1b1, Ahd4, and Nmo1 in murine skin tumors and adjacent normal epidermis by ligands of the Aryl hydrocarbon receptor by Reiners Jr, John J., Jones, Carol L., Hong, Nancy, Myrand, Scott P.

“…Products of several phase I and II genes transcriptionally activated by ligands of the aryl hydrocarbon receptor (AHR) were quantitated in cutaneous samples…”
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Stable transformation of xeroderma pigmentosum group A cells with an XPA minigene restores normal DNA repair and mutagenesis of UV-treated plasmids by Myrand, Scott P., Topping, Robert S., States, J.Christopher

“…The ability of an XPA minigene construct to complement the DNA repair defect in xeroderma pigmentosum group A (XP-A) cells was demonstrated. XP-A cells…”
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Characterization of the human XPA promoter by Topping, Robert S., Myrand, Scott P., Williams, Brandi L., Albert, Jack C., States, J.Christopher

“…We cloned the human xeroderma pigmentosum group A gene ( XPA) and characterized the XPA promoter ( pXPA) by transient cat expression. The pXPA is…”
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High-throughput genotyping method for glutathione S-transferase T1 and M1 gene deletions using TaqMan probes by Shi, M M, Myrand, S P, Bleavins, M R, de la Iglesia, F A

“…A high-throughput genotyping method has been developed to detect gene deletion polymorphisms of glutathione-S-transferase theta and mu (GSTT1 and GSTM1). This…”
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Splice site mutations in a xeroderma pigmentosum group A patient with delayed onset of neurological disease by States, J.Christopher, Myrand, Scott P.

“…XP12BE is a commonly studied XP-A cell line that exhibits slightly increased resistance to UV compared with the majority of XP-A cell lines. The elevated UV…”
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