Search Results - "Myoehaenen, S"

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer by Baylin, Stephen B, Cameron, Elizabeth E, Bachman, Kurtis E, Myöhänen, Sanna, Herman, James G

“…Densely methylated DNA associates with transcriptionally repressive chromatin characterized by the presence of underacetylated histones. Recently, these two…”
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Methylation-Specific PCR: A Novel PCR Assay for Methylation Status of CpG Islands by Herman, James G., Graff, Jeremy R., Myöhänen, Sanna, Nelkin, Barry D., Baylin, Stephen B.

“…Precise mapping of DNA methylation patterns in CpG islands has become essential for understanding diverse biological processes such as the regulation of…”
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Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation by Graff, J R, Herman, J G, Myöhänen, S, Baylin, S B, Vertino, P M

“…Promoter region CpG island methylation is associated with tumor suppressor gene silencing in neoplasia. GenBank sequence analyses revealed that a number of CpG…”
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Sequence-specific DNA Binding Activity of RNA Helicase A to the p16 super(INK4a) Promoter by Myoehaenen, S, Baylin, S B

“…p16 super(INK4a) is frequently altered in human cancer, often through epigenetically mediated transcriptional silencing. However, little is known about the…”
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Hypermethylation of the APC (adenomatous Polyposis Coli) gene promoter region in human colorectal carcinoma by Hiltunen, Mikko O., Alhonen, Leena, Koistinaho, Jari, Myöhänen, Sanna, Pääkkönen, Matti, Marin, Sinikka, Kosma, Veli‐Matti, Jänne, Juhani

“…Germline mutations of the putative tumor suppressor gene APC are associated in high frequency with the familial adenomatous polyposis, predisposing the…”
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Epigenetics of latent Epstein-Barr virus genomes: high resolution methylation analysis of the bidirectional promoter region of latent membrane protein 1 and 2B genes by Takacs, M, Salamon, D, Myöhänen, S, Li, H, Segesdi, J, Ujvari, D, Uhlig, J, Niller, H H, Wolf, H, Berencsi, G, Minarovits, J

“…We analysed the methylation patterns of CpG dinucleotides in a bidirectional promoter region (LRS, LMP 1 regulatory sequences) of latent Epstein-Barr virus…”
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Hypermethylation Can Selectively Silence Individual p16 super(ink4A) Alleles in Neoplasia by Myoehaenen, S K, Baylin, S B, Herman, J G

“…Inactivation of p16 super(ink4A) and other tumor suppressor genes has been associated with promoter region hypermethylation in neoplasia. However, direct proof…”
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De novo DNA methylation at nonrandom founder sites 5' from an unmethylated minimal origin of DNA replication in latent Epstein-Barr virus genomes by Salamon, D, Takacs, M, Myöhänen, S, Marcsek, Z, Berencsi, G, Minarovits, J

“…Latent episomal genomes of Epstein-Barr virus, a human gammaherpesvirus, represent a suitable model system for studying replication and methylation of…”
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Hypermethylation of the WT1 and calcitonin gene promoter regions at chromosome 11p in human colorectal cancer by HILTUNEN, M. O, KOISTINAHO, J, ALHONEN, L, MYÖHÄNEN, S, MARIN, S, KOSMA, V.-M, PÄÄKKÖNEN, M, JÄNNE, J

“…The short arm of the chromosome 11, known to harbour a number of putative and established tumour-suppressor genes, is frequently hypermethylated in various…”
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Tissue-specific expression of the diazepam-binding inhibitor in Drosophila melanogaster: cloning, structure, and localization of the gene by Kolmer, M, Roos, C, Tirronen, M, Myoehaenen, S, Alho, H

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Generation of Transgenic Dairy Cattle from Transgene-Analyzed and Sexed Embryos Produced In Vitro by Hyttinen, Juha-Matti, Peura, Teija, Tolvanen, Minna, Aalto, Jussi, Alhonen, Leena, Sinervirta, Riitta, Halmekytö, Maria, Myöhänen, Sanna, Jänne, Juhani

“…We have generated a transgenic calf from in vitro produced bovine embryos which had undergone transgene analysis and sexing prior to the embryo transfer…”
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Kinds of mutations induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in the hprt gene of Chinese hamster ovary cells by Hyttinen, Juha M.T., Myöhänen, Sanna, Jansson, Kristian

“…The kinds of mutations induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in the protein coding region of the hprt gene of Chinese hamster…”
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High-level expression of bovine β-lactoglobulin gene in transgenic mice by Hyttinen, Juha-Matti, Korhonen, Veli-Pekka, Hiltunen, Mikko O, Myöhänen, Sanna, Jänne, Juhani

“…To study the expression of the bovine β-lactoglobulin (BLG) gene we isolated the BLG gene from a genomic library and introduced it into murine germline. Bovine…”
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Reverse fluorescent sequencing of large M13 clones by Myöhänen, S, Wahlfors, J

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Human spermidine synthase gene: structure and chromosomal localization by Myöhänen, S, Kauppinen, L, Wahlfors, J, Alhonen, L, Jänne, J

“…The human spermidine synthase (EC 2.5.1.16) gene was isolated from a genomic library constructed with DNA obtained from a human immunoglobulin G (IgG) myeloma…”
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