Search Results - "Mynatt, R. L."

Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT) by Truett, G E, Heeger, P, Mynatt, R L, Truett, A A, Walker, J A, Warman, M L

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Inhibition of carnitine palymitoyltransferase1b induces cardiac hypertrophy and mortality in mice by Haynie, K. R., Vandanmagsar, B., Wicks, S. E., Zhang, J., Mynatt, R. L.

“…Recent reports suggest that short‐term pharmacological carnitine palmitoyltransferase 1 (Cpt1) inhibition improves skeletal muscle glucose tolerance and…”
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Carnitine revisited: potential use as adjunctive treatment in diabetes by Power, R. A, Hulver, M. W, Zhang, J. Y, Dubois, J, Marchand, R. M, Ilkayeva, O, Muoio, D. M, Mynatt, R. L

“…Aims/hypothesis This study examined the efficacy of supplemental l-carnitine as an adjunctive diabetes therapy in mouse models of metabolic disease. We…”
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Secreted proteins and genes in fetal and neonatal pig adipose tissue and stromal-vascular cells by Hausman, G.J, Poulos, S.P, Richardson, R.L, Barb, C.R, Andacht, T, Kirk, H.C, Mynatt, R.L

“…Although microarray and proteomic studies have indicated the expression of unique and unexpected genes and their products in human and rodent adipose tissue,…”
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The role of the agouti gene in the yellow obese syndrome by Miltenberger, R J, Mynatt, R L, Wilkinson, J E, Woychik, R P

“…The yellow obese syndrome in mice encompasses many pleiotropic effects including yellow fur, maturity-onset obesity, hyperinsulinemia, insulin resistance,…”
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Combined effects of insulin treatment and adipose tissue-specific agouti expression on the development of obesity by Mynatt, R.L, Miltenberger, R.J, Klebig, M.L, Zemel, M.B, Wilkinson, J.E, Wilkison, W.O, Woychik, R.P

“…The agouti gene product is a secreted protein that acts in a paracrine manner to regulate coat color in mammals. Several dominant mutations at the agouti locus…”
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Artemisia dracunculus L. extract ameliorates insulin sensitivity by attenuating inflammatory signalling in human skeletal muscle culture by Vandanmagsar, B., Haynie, K. R., Wicks, S. E., Bermudez, E. M., Mendoza, T. M., Ribnicky, D., Cefalu, W. T., Mynatt, R. L.

“…Aims Bioactives of Artemisia dracunculus L. (termed PMI 5011) have been shown to improve insulin action by increasing insulin signalling in skeletal muscle…”
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An Agouti Mutation Lacking the Basic Domain Induces Yellow Pigmentation but Not Obesity in Transgenic Mice by Miltenberger, R. J., Mynatt, R. L., Bruce, B. D., Wilkison, W. O., Woychik, R. P., Michaud, E. J.

“…Chronic antagonism of melanocortin receptors by the paracrine-acting agouti gene product induces both yellow fur and a maturity-onset obesity syndrome in mice…”
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Macronutrient Diet Intake of the Lethal Yellow Agouti (A y/a) Mouse by Koegler, Frank H., Schaffhauser, Andrea O., Mynatt, Randall L., York, David A., Bray, George A.

“…To examine the effect of chronic endogenous melanocortin receptor (MC-R) antagonism on macronutrient diet selection, A y/a mice that ectopically overexpress…”
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Cholate extracts of mitochondrial outer membranes increase inhibition by malonyl-CoA of carnitine palmitoyltransferase-I by a mechanism involving phospholipids by MYNATT, R. L, GREENHAW, J. J, COOK, G. A

“…It has been reported that sodium cholate can separate the catalytic component of carnitine palmitoyltransferase-I (CPT-I) from a putative malonyl-CoA-binding…”
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Mesenchymal stem cells from the outer ear: a novel adult stem cell model system for the study of adipogenesis by Rim, Jong-Seop, Mynatt, Randall L, Gawronska-Kozak, Barbara

“…ABSTRACTAdipocytes arise from multipotent stem cells of mesodermal origin, which also give rise to the muscle, bone, and cartilage lineages. However, signals…”
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Role of the agouti gene in obesity by Michaud, EJ, Mynatt, RL, Miltenberger, RJ, Klebig, ML, Wilkinson, JE, Zemel, MB, Wilkison, WO, Woychik, RP

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Targeted deletion of melanocortin receptor subtypes 3 and 4, but not CART, alters nutrient partitioning and compromises behavioral and metabolic responses to leptin by Zhang, Yubin, Kilroy, Gail E, Henagan, Tara M, Prpic-Uhing, Vera, Richards, William G, Bannon, Anthony W, Mynatt, Randall L, Gettys, Thomas W

“…Mouse lines with targeted disruption of the cocaine amphetamine-related transcript (CART), melanocortin receptor 3 (MCR3), or melanocortin receptor 4 (MCR4)…”
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IL-17 Stimulates Granulopoiesis in Mice: Use of an Alternate, Novel Gene Therapy-Derived Method for In Vivo Evaluation of Cytokines by Schwarzenberger, Paul, La Russa, Vincent, Miller, Allan, Ye, Peng, Huang, Weitao, Zieske, Arthur, Nelson, Steve, Bagby, Gregory J, Stoltz, David, Mynatt, Randall L, Spriggs, Melanie, Kolls, Jay K

“…IL-17 is a novel cytokine secreted principally by CD4+ T cells. It has been shown to support the growth of hemopoietic progenitors in vitro; however, its in…”
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The Regulation and Activation of Ciliary Neurotrophic Factor Signaling Proteins in Adipocytes by Zvonic, Sanjin, Cornelius, Peter, Stewart, William C, Mynatt, Randall L, Stephens, Jacqueline M

“…Ciliary neurotrophic factor (CNTF) is primarily known for its roles as a lesion factor released by the ruptured glial cells that prevent neuronal degeneration…”
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Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I by Park, E A, Mynatt, R L, Cook, G A, Kashfi, K

“…The regulation of hepatic mitochondrial carnitine palmitoyltransferase-I (CPT-I) was studied in rats during starvation and insulin-dependent diabetes and in…”
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Modulation of the malonyl-CoA sensitivity of hepatic carnitine palmitoyltransferase (CPT) by phospholipids by Mynatt, R L, Cook, G A

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Agouti regulates adipocyte transcription factors by Mynatt, R L, Stephens, J M

“…Agouti is a secreted paracrine factor that regulates pigmentation in hair follicle melanocytes. Several dominant mutations cause ectopic expression of agouti,…”
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Differential RNA expression of hepatic tissue in lean and obese mice after LPS-induced systemic inflammation by Scott, L Keith, Vachharajani, Vidula, Minagar, Alireza, Mynatt, Randall L, Conrad, Steven A

“…Mortality of obese patients with sepsis has been reported to be significantly higher than lean patients. The underlying basis for this difference is not…”
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The effects of calcium channel blockade on agouti-induced obesity by Kim, J H, Mynatt, R L, Moore, J W, Woychik, R P, Moustaid, N, Zemel, M B

“…We have previously observed that obese viable yellow (Avy/a) mice exhibit increased intracellular Ca2+ ([Ca2+]i) and fatty acid synthase (FAS) gene expression;…”
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