Search Results - "Mylroie, Hayley"
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Identification of cyclins A1, E1 and vimentin as downstream targets of heme oxygenase-1 in vascular endothelial growth factor-mediated angiogenesis
Published in Scientific reports (08-07-2016)“…Angiogenesis is an essential physiological process and an important factor in disease pathogenesis. However, its exploitation as a clinical target has achieved…”
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Journal Article -
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PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis
Published in Cardiovascular research (01-06-2015)“…Vascular injury leading to endothelial dysfunction is a characteristic feature of chronic renal disease, diabetes mellitus, and systemic inflammatory…”
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Journal Article -
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Protein kinase Cε activity induces anti-inflammatory and anti-apoptotic genes via an ERK1/2- and NF-κB-dependent pathway to enhance vascular protection
Published in Biochemical journal (15-10-2012)“…Vascular endothelial injury predisposes to endothelial dysfunction and atherogenesis. We have investigated the hypothesis that PKCε (protein kinase Cε) is an…”
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Journal Article -
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Vascular protection during systemic inflammation: investigation of the relationship between pkc epsilon and heme oxygenase-1
Published 01-01-2012“…Background: Patients with chronic inflammatory diseases including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) demonstrate endothelial…”
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Dissertation -
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Investigation of the regulatory role of heme oxygenase-1 and its products in VEGF-mediated angiogenesis
Published in Vascular pharmacology (01-05-2012)Get full text
Journal Article