Search Results - "Myles, R"

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease by Minter, Myles R., Taylor, Juliet M., Crack, Peter J.

“…Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most common cause of dementia. Deposition of amyloid‐β (Aβ) remains a hallmark…”
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Drivers of peak warming in a consumption-maximizing world by Allen, Myles R.

“…An analysis of climate change mitigation policies in an idealized integrated assessment framework highlights the importance of economic growth, and investment…”
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Constraining the Ratio of Global Warming to Cumulative CO₂ Emissions Using CMIP5 Simulations by Gillett, Nathan P., Arora, Vivek K., Matthews, Damon, Allen, Myles R.

“…The ratio of warming to cumulative emissions of carbon dioxide has been shown to be approximately independent of time and emissions scenarios and directly…”
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Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease by Minter, Myles R., Zhang, Can, Leone, Vanessa, Ringus, Daina L., Zhang, Xiaoqiong, Oyler-Castrillo, Paul, Musch, Mark W., Liao, Fan, Ward, Joseph F., Holtzman, David M., Chang, Eugene B., Tanzi, Rudolph E., Sisodia, Sangram S.

“…Severe amyloidosis and plaque-localized neuro-inflammation are key pathological features of Alzheimer’s disease (AD). In addition to astrocyte and microglial…”
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Focus on cumulative emissions, global carbon budgets and the implications for climate mitigation targets by Matthews, H Damon, Zickfeld, Kirsten, Knutti, Reto, Allen, Myles R

“…The Environmental Research Letters focus issue on 'Cumulative Emissions, Global Carbon Budgets and the Implications for Climate Mitigation Targets' was…”
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Higher CO2 concentrations increase extreme event risk in a 1.5 °C world by Baker, Hugh S., Millar, Richard J., Karoly, David J., Beyerle, Urs, Guillod, Benoit P., Mitchell, Dann, Shiogama, Hideo, Sparrow, Sarah, Woollings, Tim, Allen, Myles R.

“…The Paris Agreement 1 aims to ‘pursue efforts to limit the temperature increase to 1.5 °C above pre-industrial levels.’ However, it has been suggested that…”
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Frequency and features of malignant tumors clinically mimicking cutaneous cysts: A retrospective chart review by McCrary, Myles R., Foulis, Philip, Gibbs, Julie

“…Background Many cutaneous lesions are clinically suspected as “cyst”; however, following histopathological examination, are found to be more significant…”
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Forecast-based attribution of a winter heatwave within the limit of predictability by Leach, Nicholas J., Weisheimer, Antje, Allen, Myles R., Palmer, Tim

“…Attribution of extreme weather events has expanded rapidly as a field over the past decade. However, deficiencies in climate model representation of key…”
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New use of global warming potentials to compare cumulative and short-lived climate pollutants by Allen, Myles R., Fuglestvedt, Jan S., Shine, Keith P., Reisinger, Andy, Pierrehumbert, Raymond T., Forster, Piers M.

“…This study presents a new use of a widely used metric known as the global warming potential (GWP) to compare the impact of cumulative climate pollutants such…”
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Anthropogenic greenhouse gas contribution to flood risk in England and Wales in autumn 2000 by Pall, Pardeep, Aina, Tolu, Stone, Dáithí A., Stott, Peter A., Nozawa, Toru, Hilberts, Arno G. J., Lohmann, Dag, Allen, Myles R.

“…Human input to autumn 2000 floods Human emissions of greenhouse gases — and related warming — are recognized as an influence on global and regional warming and…”
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The many possible climates from the Paris Agreement’s aim of 1.5 °C warming by Seneviratne, Sonia I., Rogelj, Joeri, Séférian, Roland, Wartenburger, Richard, Allen, Myles R., Cain, Michelle, Millar, Richard J., Ebi, Kristie L., Ellis, Neville, Hoegh-Guldberg, Ove, Payne, Antony J., Schleussner, Carl-Friedrich, Tschakert, Petra, Warren, Rachel F.

“…The United Nations’ Paris Agreement includes the aim of pursuing efforts to limit global warming to only 1.5 °C above pre-industrial levels. However, it is not…”
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Emission budgets and pathways consistent with limiting warming to 1.5 °C by Millar, Richard J., Fuglestvedt, Jan S., Friedlingstein, Pierre, Rogelj, Joeri, Grubb, Michael J., Matthews, H. Damon, Skeie, Ragnhild B., Forster, Piers M., Frame, David J., Allen, Myles R.

“…The Paris Agreement has opened debate on whether limiting warming to 1.5 °C is compatible with current emission pledges and warming of about 0.9 °C from the…”
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Improved calculation of warming-equivalent emissions for short-lived climate pollutants by Cain, Michelle, Lynch, John, Allen, Myles R., Fuglestvedt, Jan S., Frame, David J., Macey, Adrian H

“…Anthropogenic global warming at a given time is largely determined by the cumulative total emissions (or stock) of long-lived climate pollutants (LLCPs),…”
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A solution to the misrepresentations of CO2-equivalent emissions of short-lived climate pollutants under ambitious mitigation by Allen, Myles R., Shine, Keith P., Fuglestvedt, Jan S., Millar, Richard J., Cain, Michelle, Frame, David J., Macey, Adrian H.

“…While cumulative carbon dioxide (CO 2 ) emissions dominate anthropogenic warming over centuries, temperatures over the coming decades are also strongly…”
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Cell-targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules by Veetil, Aneesh T., Chakraborty, Kasturi, Xiao, Kangni, Minter, Myles R., Sisodia, Sangram S., Krishnan, Yamuna

“…Achieving triggered release of small molecules with spatial and temporal precision at designated cells within an organism remains a challenge. By combining a…”
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Uncertain impacts on economic growth when stabilizing global temperatures at 1.5°C or 2°C warming by Pretis, Felix, Schwarz, Moritz, Tang, Kevin, Haustein, Karsten, Allen, Myles R.

“…Empirical evidence suggests that variations in climate affect economic growth across countries over time. However, little is known about the relative impacts…”
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S3749 A Case of De Novo Hepatocellular Cancer Following Liver Transplantation by Bhaskar, Sonya, Räsänen, Kati, McCrary, Myles R., Agrawal, Saurabh

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S3750 Extrahepatic Hepatocellular Carcinoma Recurrence 5 Years After Liver Transplant by Bhaskar, Sonya, McCrary, Myles R., Räsänen, Kati, Agrawal, Saurabh

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Type-I interferon pathway in neuroinflammation and neurodegeneration: focus on Alzheimer’s disease by Taylor, Juliet M., Moore, Zachery, Minter, Myles R., Crack, Peter J.

“…Past research in Alzheimer’s disease (AD) has largely been driven by the amyloid hypothesis; the accompanying neuroinflammation seen in AD has been assumed to…”
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Greenhouse-gas emission targets for limiting global warming to 2 degrees C by Meinshausen, Malte, Meinshausen, Nicolai, Hare, William, Raper, Sarah C B, Frieler, Katja, Knutti, Reto, Frame, David J, Allen, Myles R

“…More than 100 countries have adopted a global warming limit of 2 degrees C or below (relative to pre-industrial levels) as a guiding principle for mitigation…”
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