Search Results - "Mygind, Kasper J"

ADAM12-Generated Basigin Ectodomain Binds β1 Integrin and Enhances the Expression of Cancer-Related Extracellular Matrix Proteins by Mygind, Kasper J, Nikodemus, Denise, Gnosa, Sebastian, Kweder, Ramya, Albrechtsen, Nicolai J Wewer, Kveiborg, Marie, Erler, Janine T, Albrechtsen, Reidar

“…Desmoplasia is a common feature of aggressive cancers, driven by a complex interplay of protein production and degradation. Basigin is a type 1 integral…”
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Sorting nexin 9 (SNX9) regulates levels of the transmembrane ADAM9 at the cell surface by Mygind, Kasper J., Störiko, Theresa, Freiberg, Marie L., Samsøe-Petersen, Jacob, Schwarz, Jeanette, Andersen, Olav M., Kveiborg, Marie

“…ADAM9 is an active member of the family of transmembrane ADAMs (a disintegrin and metalloproteases). It plays a role in processes such as bone formation and…”
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Loss of ADAM9 expression impairs β1 integrin endocytosis, focal adhesion formation and cancer cell migration by Mygind, Kasper J, Schwarz, Jeanette, Sahgal, Pranshu, Ivaska, Johanna, Kveiborg, Marie

“…The transmembrane protease ADAM9 is frequently upregulated in human cancers, and it promotes tumour progression in mice. , ADAM9 regulates cancer cell adhesion…”
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