Search Results - "Myers, Rebecca S."
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A Network of Conserved Interactions Regulates the Allosteric Signal in a Glutamine Amidotransferase
Published in Biochemistry (Easton) (27-02-2007)“…We have combined equilibrium and steered molecular dynamics (SMD) simulations with principal component and correlation analyses to probe the mechanism of…”
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Journal Article -
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Crystal Structure of Imidazole Glycerol Phosphate Synthase: A Tunnel through a (β/α) 8 Barrel Joins Two Active Sites
Published in Structure (London) (01-10-2001)“…Background: Imidazole glycerol phosphate synthase catalyzes a two-step reaction of histidine biosynthesis at the bifurcation point with the purine de novo…”
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Journal Article -
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Reaction Coupling through Interdomain Contacts in Imidazole Glycerol Phosphate Synthase
Published in Biochemistry (Easton) (13-09-2005)“…Imidazole glycerol phosphate (IGP) synthase, a triad glutamine amidotransferase, catalyzes the fifth step in the histidine biosynthetic pathway, where ammonia…”
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Toward Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerolphosphate Synthase: Crystal Structures of a Ternary Complex and the Free Enzyme
Published in Biochemistry (Easton) (17-06-2003)“…Imidazole glycerol phosphate synthase catalyzes formation of the imidazole ring in histidine biosynthesis. The enzyme is also a glutamine amidotransferase,…”
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Journal Article -
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Structural Elements in IGP Synthase Exclude Water to Optimize Ammonia Transfer
Published in Biophysical journal (01-07-2005)“…In the complex pathway of histidine biosynthesis, a key branch point linking amino acid and purine biosynthesis is catalyzed by the bifunctional enzyme…”
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Journal Article -
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Substrate-Induced Changes in the Ammonia Channel for Imidazole Glycerol Phosphate Synthase
Published in Biochemistry (Easton) (17-06-2003)“…IGP synthase is a glutamine amidotransferase that incorporates ammonia derived from glutamine into the unusual nucleotide, N…”
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Journal Article -
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Crystal Structure of Methanobacterium thermoautotrophicum Phosphoribosyl-AMP Cyclohydrolase HisI
Published in Biochemistry (Easton) (02-08-2005)“…The metabolic pathway for histidine biosynthesis is interesting from an evolutionary perspective because of the diversity of gene organizations and protein…”
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Journal Article -
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Crystal Structure of Imidazole Glycerol Phosphate Synthase
Published in Structure (London) (01-10-2001)Get full text
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Healing the Disaster of Slavery: The Maafa Suite at St. Paul's Community Baptist Church, Brooklyn, New York
Published in Anglican and Episcopal History (01-12-2014)“…The word describes the suffering of African Americans by means of slavery, colonialism, and other forms of oppression throughout history. Because of the trauma…”
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Book Review Journal Article -
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Imidazole glycerol phosphate synthase: Structural and kinetic studies of a triad glutamine amidotransferase
Published 01-01-2005“…Imidazole glycerol phosphate (IGP) synthase is a glutamine amidotransferase (GAT) that incorporates ammonia derived from glutamine into the unusual nucleotide,…”
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Dissertation -
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A General High-Performance Liquid Chromatography-Based Assay for the Hydrolysis of N-Acyl Glutamates
Published in Analytical biochemistry (15-11-1999)“…A rapid and simple HPLC assay has been developed to separate and quantify N-acyl glutamates and the corresponding carboxylic acids of the acyl moiety. This…”
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Journal Article