Search Results - "Myers, R.M."

Association of DRD2 and DRD3 polymorphisms with Parkinson's disease in a multiethnic consortium by McGuire, V, Den Eeden, S.K. Van, Tanner, C.M, Kamel, F, Umbach, D.M, Marder, K, Mayeux, R, Ritz, B, Ross, G.W, Petrovitch, H, Topol, B, Popat, R.A, Costello, S, Manthripragada, A.D, Southwick, A, Myers, R.M, Nelson, L.M

“…Abstract Objective To examine genetic associations of polymorphisms in the dopamine receptor D2 ( DRD2 ) and D3 ( DRD3 ) genes with risk of Parkinson's disease…”
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DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles by Evans, S.J, Choudary, P.V, Vawter, M.P, Li, J, Meador-Woodruff, J.H, Lopez, J.F, Burke, S.M, Thompson, R.C, Myers, R.M, Jones, E.G, Bunney, W.E, Watson, S.J, Akil, H

“…Transcriptional profiles within discrete human brain regions are likely to reflect structural and functional specialization. Using DNA microarray technology,…”
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Mutation of the prion protein gene at codon 208 in familial Creutzfeldt-Jakob disease by MASTRIANNI, J. A, IANNICOLA, C, MYERS, R. M, DEARMOND, S, PRUSINER, S. B

“…Four point mutations and one insertion within the prion protein (PrP) gene have been tightly linked to the development of inherited prion disease. We developed…”
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Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder by Bunney, B G, Li, J Z, Walsh, D M, Stein, R, Vawter, M P, Cartagena, P, Barchas, J D, Schatzberg, A F, Myers, R M, Watson, S J, Akil, H, Bunney, W E

“…Conventional antidepressants require 2–8 weeks for a full clinical response. In contrast, two rapidly acting antidepressant interventions, low-dose ketamine…”
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Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression by Bernard, R, Kerman, I A, Thompson, R C, Jones, E G, Bunney, W E, Barchas, J D, Schatzberg, A F, Myers, R M, Akil, H, Watson, S J

“…Several studies have proposed that brain glutamate signaling abnormalities and glial pathology have a role in the etiology of major depressive disorder (MDD)…”
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Systematic reanalysis of genomic data improves quality of variant interpretation by Hiatt, S.M., Amaral, M.D., Bowling, K.M., Finnila, C.R., Thompson, M.L., Gray, D.E., Lawlor, J.M.J., Cochran, J.N., Bebin, E.M., Brothers, K.B., East, K.M., Kelley, W.V., Lamb, N.E., Levy, S.E., Lose, E.J., Neu, M.B., Rich, C.A., Simmons, S., Myers, R.M., Barsh, G.S., Cooper, G.M.

“…As genomic sequencing expands, so does our knowledge of the link between genetic variation and disease. Deeper catalogs of variant frequencies improve…”
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Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson's disease by Popat, R. A., Van Den Eeden, S. K., Tanner, C. M., Kamel, F., Umbach, D. M., Marder, K., Mayeux, R., Ritz, B., Ross, G. W., Petrovitch, H., Topol, B., McGuire, V., Costello, S., Manthripragada, A. D., Southwick, A., Myers, R. M., Nelson, L. M.

“…Background and purpose:  In 1‐methyl‐4‐phenyl 1,2,3,6‐tetrahydropyridine animal models of Parkinson’s disease (PD), caffeine protects neurons by blocking the…”
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Quantitative validation of immunofluorescence and lectin staining using reduced CLARITY acrylamide formulations by Krolewski, D. M., Kumar, V., Martin, B., Tomer, R., Deisseroth, K., Myers, R. M., Schatzberg, A. F., Lee, F. S., Barchas, J. D., Bunney, W. E., Akil, H., Watson, S. J.

“…The CLARITY technique enables three-dimensional visualization of fluorescent-labeled biomolecules in clarified intact brain samples, affording a unique view of…”
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Preclinical efficacy of the oncolytic measles virus expressing the sodium iodide symporter in iodine non-avid anaplastic thyroid cancer: a novel therapeutic agent allowing noninvasive imaging and radioiodine therapy by Reddi, H V, Madde, P, McDonough, S J, Trujillo, M A, Morris, J C, Myers, R M, Peng, K W, Russell, S J, McIver, B, Eberhardt, N L

“…Anaplastic thyroid cancer is an extremely aggressive disease resistant to radioiodine treatment because of loss of sodium iodide symporter (NIS) expression. To…”
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Stress-induced changes in primate prefrontal profiles of gene expression by KARSSEN, Am, HER, S, SCHATZBERG, A. F, LYONS, D. M, LI, J. Z, PATEL, P. D, MENG, F, BUNNEY, We, JONES, E. G, WATSON, S. J, AKIL, H, MYERS, R. M

“…Stressful experiences that consistently increase cortisol levels appear to alter the expression of hundreds of genes in prefrontal limbic brain regions. Here,…”
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FPGA-based embedded Linux technology in fusion: The MAST microwave imaging system by Huang, B.K., Vann, R.G.L., Freethy, S., Myers, R.M., Naylor, G., Sharples, R.M., Shevchenko, V.F.

“…► Present an FPGA architecture using embedded Linux. ► Present a cutting edge 8GB/s FPGA data acquisition system. ► Achieve ethernet throughput up to 83MB/s on…”
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Measuring genetic change in a dairy herd using a control population by Legates, J E, Myers, R M

“…A selection experiment was conducted to assess the change in production resulting from selection with artificial insemination using a randomly maintained…”
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Synthesis of the thapsigargins by Ley, S.V, Antonello, A, Balskus, E.P, Booth, D.T, Christensen, S.B, Cleator, E, Gold, H, Hogenauer, K, Hunger, U, Myers, R.M

“…The thapsigargins are a family of complex guaianolides with potent and selective Ca2+-modulating properties. This article documents the evolution of a…”
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Radiation Hybrid Mapping: A Somatic Cell Genetic Method for Constructing High-Resolution Maps of Mammalian Chromosomes by Cox, David R., Burmeister, Margit, Price, E. Roydon, Kim, Suwon, Myers, Richard M.

“…Radiation hybrid (RH) mapping, a somatic cell genetic technique, was developed as a general approach for constructing long-range maps of mammalian chromosomes…”
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Coding SNPs included in exon arrays for the study of psychiatric disorders by Sequeira, A, Meng, F, Rollins, B, Myers, R M, Jones, E G, Watson, S J, Akil, H, Schatzberg, A F, Barchas, J, Bunney, W E, Vawter, M P

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Wavefront correction using a self-referencing phase conjugation system based on a Zernike cell by Dale, S.R., Love, G.D., Myers, R.M., Naumov, A.F.

“…A wavefront correction system was produced using a phase conjugating method based on a point diffraction interferometer, or Zernike cell. This has the main…”
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Assessing the quality of finished genomic sequence by Schmutz, J, Wheeler, J, Grimwood, J, Dickson, M, Myers, R M

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Segregation of the Huntington disease region of human chromosome 4 in a somatic cell hybrid by Cox, D R, Pritchard, C A, Uglum, E, Casher, D, Kobori, J, Myers, R M

“…We have developed an X-irradiation:cell fusion procedure that segregates segments of human chromosomes lacking selectable markers and have used this approach…”
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LETTER TO THE EDITOR by Henry, R.D., Herbarium, R.M. Myers

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The MARTINI adaptive optics instrument by Doel, A.P., Dunlop, C.N., Buscher, D.F., Myers, R.M., Sharples, R.M., Major, J.V.

“…The Multi-Aperture Real Time Image Normalisation Instrument (MARTINI) is an adaptive optics system designed to operate at one of the Nasmyth focal stations of…”
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