Search Results - "Myers, Dean A"

Early and mid-gestation Zika virus (ZIKV) infection in the olive baboon (Papio anubis) leads to fetal CNS pathology by term gestation by Gurung, Sunam, Reuter, Darlene, Norris, Abby, Dubois, Molly, Maxted, Marta, Singleton, Krista, Castillo-Castrejon, Marisol, Papin, James F., Myers, Dean A.

“…Zika virus (ZIKV) infection in pregnancy can produce catastrophic teratogenic damage to the developing fetus including microcephaly and congenital Zika…”
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Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon by Gurung, Sunam, Reuter, Nicole, Preno, Alisha, Dubaut, Jamie, Nadeau, Hugh, Hyatt, Kimberly, Singleton, Krista, Martin, Ashley, Parks, W Tony, Papin, James F, Myers, Dean A

“…Zika virus (ZIKV) infection during pregnancy in humans is associated with an increased incidence of congenital anomalies including microcephaly as well as…”
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Translational Model of Zika Virus Disease in Baboons by Gurung, Sunam, Preno, Alisha N, Dubaut, Jamie P, Nadeau, Hugh, Hyatt, Kimberly, Reuter, Nicole, Nehete, Bharti, Wolf, Roman F, Nehete, Pramod, Dittmer, Dirk P, Myers, Dean A, Papin, James F

“…Zika virus (ZIKV) is an emerging mosquito-borne flavivirus with devastating outcomes seen recently in the Americas due to the association of maternal ZIKV…”
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eNOS activation and NO function: Differential control of steroidogenesis by nitric oxide and its adaptation with hypoxia by Ducsay, Charles A, Myers, Dean A

“…Nitric oxide (NO) plays a role in a wide range of physiological processes. Aside from its widely studied function in the regulation of vascular function, NO…”
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The Isolation and In Vitro Differentiation of Primary Fetal Baboon Tracheal Epithelial Cells for the Study of SARS-CoV-2 Host-Virus Interactions by Subramaniyan, Bharathiraja, Gurung, Sunam, Bodas, Manish, Moore, Andrew R, Larabee, Jason L, Reuter, Darlene, Georgescu, Constantin, Wren, Jonathan D, Myers, Dean A, Papin, James F, Walters, Matthew S

“…The mucociliary airway epithelium lines the human airways and is the primary site of host-environmental interactions in the lung. Following virus infection,…”
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Characterization of the SARS-CoV-2 Host Response in Primary Human Airway Epithelial Cells from Aged Individuals by Subramaniyan, Bharathiraja, Larabee, Jason L, Bodas, Manish, Moore, Andrew R, Burgett, Anthony W G, Myers, Dean A, Georgescu, Constantin, Wren, Jonathan D, Papin, James F, Walters, Matthew S

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), a global pandemic characterized by…”
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Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat by Vargas, Vladimir E, Gurung, Sunam, Grant, Benjamin, Hyatt, Kimberly, Singleton, Krista, Myers, Sarah M, Saunders, Debra, Njoku, Charity, Towner, Rheal, Myers, Dean A

“…The effect of gestational hypoxia on the neonatal leptin surge, development of hypothalamic arcuate nuclei (ARH) projections and appetite that could contribute…”
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Clinical Insights for Cervical Ripening and Labor Induction Using Prostaglandins by Pierce, Stephanie, Bakker, Ronan, Myers, Dean A, Edwards, Rodney K

“…Cervical ripening is often the first component of labor induction and is used to facilitate the softening and thinning of the cervix in preparation for labor…”
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Anatomical Distribution and Cellular Basis for High Levels of Aromatase Activity in the Brain of Teleost Fish: Aromatase Enzyme and mRNA Expression Identify Glia as Source by Forlano, Paul M, Deitcher, David L, Myers, Dean A, Bass, Andrew H

“…Although teleost fish have higher levels of brain aromatase activity than any other vertebrate group, its function remains speculative, and no study has…”
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Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver by Sugino, Kameron Y, Mandala, Ashok, Janssen, Rachel C, Gurung, Sunam, Trammell, MaJoi, Day, Michael W, Brush, Richard S, Papin, James F, Dyer, David W, Agbaga, Martin-Paul, Friedman, Jacob E, Castillo-Castrejon, Marisol, Jonscher, Karen R, Myers, Dean A

“…Maternal consumption of a high-fat, Western-style diet (WD) disrupts the maternal/infant microbiome and contributes to developmental programming of the immune…”
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Long term hypoxia during gestation alters perirenal adipose tissue gene expression in the lamb by Myers, Dean A., Singleton, Krista, Hyatt, Kim, Kaushal, Kanchan M., Ducsay, Charles A.

“…We previously reported that following long-term hypoxia (LTH), the ovine foetus exhibits enhanced expression of brown/beige adipose genes. This study was…”
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Corticosterone delivery to the amygdala increases corticotropin-releasing factor mRNA in the central amygdaloid nucleus and anxiety-like behavior by Shepard, Jack D, Barron, Kirk W, Myers, Dean A

“…The present study examined the effects of stereotaxic delivery of corticosterone to the amygdala on anxiety-like behavior and corticotropin-releasing factor…”
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The Recruitment and Activation of Leukocytes into the Immune Cervix: Further Support That Cervical Remodeling Involves an Immune and Inflammatory Mechanism by Myers, Dean A

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Adrenocortical and Adipose Responses to High-Altitude-Induced, Long-Term Hypoxia in the Ovine Fetus by Myers, Dean A., Ducsay, Charles A.

“…By late gestation, the maturing hypothalamo-pituitary-adrenal (HPA) axis aids the fetus in responding to stress. Hypoxia represents a significant threat to the…”
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Corticosterone implants to the amygdala and type 1 CRH receptor regulation: Effects on behavior and colonic sensitivity by Myers, Dean A., Gibson, Matthew, Schulkin, Jay, Van-Meerveld, Beverley Greenwood

“…Corticosterone (CORT) micropellets were stereotaxically placed bilaterally at the dorsal margin of the central nucleus of the amygala (CeA). Both behavioral…”
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Zika Virus Infection, Reproductive Organ Targeting, and Semen Transmission in the Male Olive Baboon by Peregrine, Jamie, Gurung, Sunam, Lindgren, Mark C, Husain, Sanam, Zavy, Michael T, Myers, Dean A, Papin, James F

“…Zika virus (ZIKV) infection in pregnant women is a serious threat to the development and viability of the fetus. The primary mode of ZIKV transmission to…”
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Maternal Zika Virus (ZIKV) Infection following Vaginal Inoculation with ZIKV-Infected Semen in Timed-Pregnant Olive Baboons by Gurung, Sunam, Nadeau, Hugh, Maxted, Marta, Peregrine, Jamie, Reuter, Darlene, Norris, Abby, Edwards, Rodney, Hyatt, Kimberly, Singleton, Krista, Papin, James F, Myers, Dean A

“…Zika virus (ZIKV) infection is now firmly linked to congenital Zika syndrome (CZS), including fetal microcephaly. While species of mosquito are the primary…”
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Fetal endocrine and metabolic adaptations to hypoxia: the role of the hypothalamic-pituitary-adrenal axis by Newby, Elizabeth A, Myers, Dean A, Ducsay, Charles A

“…In utero, hypoxia is a significant yet common stress that perturbs homeostasis and can occur due to preeclampsia, preterm labor, maternal smoking, heart or…”
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Cognitive differences between Sprague-Dawley rats selectively bred for sensitivity or resistance to diet induced obesity by Gurung, Sunam, Agbaga, Martin-Paul, Myers, Dean A.

“…•Adult male rats bred for sensitivity to diet-induced obesity (DIO) exhibit obesity independent memory impairment.•DIO rats showed increased indices of…”
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Up-Regulation of the Fetal Baboon Hypothalamo-Pituitary-Adrenal Axis in Intrauterine Growth Restriction: Coincidence with Hypothalamic Glucocorticoid Receptor Insensitivity and Leptin Receptor Down-Regulation by Li, Cun, Ramahi, Emma, Nijland, Mark J, Choi, Jaeyhek, Myers, Dean A, Nathanielsz, Peter W, McDonald, Thomas J

“…Intrauterine growth restriction (IUGR) is an important fetal developmental problem resulting from 2 broad causes: maternal undernutrition and/or decreased…”
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