Search Results - "Myers, Brenna"

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  1. 1
    Dynamics of Thermodynamically Stable, Kinetically Trapped, and Inhibitor-Bound States of Pepsin

    Dynamics of Thermodynamically Stable, Kinetically Trapped, and Inhibitor-Bound States of Pepsin by Dee, Derek R., Myers, Brenna, Yada, Rickey Y.

    Published in Biophysical journal (05-10-2011)
    “…The pepsin folding mechanism involves a prosegment (PS) domain that catalyzes folding, which is then removed, resulting in a kinetically trapped native state…”
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  2. 2
    Foldase and inhibitor functionalities of the pepsinogen prosegment are encoded within discrete segments of the 44 residue domain

    Foldase and inhibitor functionalities of the pepsinogen prosegment are encoded within discrete segments of the 44 residue domain by Dee, Derek R., Myers, Brenna, Yada, Rickey Y.

    Published in Biochimica et biophysica acta (01-10-2015)
    “…Pepsin is initially produced as the zymogen pepsinogen, containing a 44 residue prosegment (PS) domain. When folded without the PS, pepsin forms a…”
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