Search Results - "Myers, Allen C."

TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis by Oh, Min-Hee, Oh, Sun Young, Lu, Jingning, Lou, Hongfei, Myers, Allen C, Zhu, Zhou, Zheng, Tao

“…Chronic debilitating pruritus is a cardinal feature of atopic dermatitis (AD). Little is known about the underlying mechanisms. Antihistamines lack efficacy in…”
Get full text

Melanopsin mediates light-dependent relaxation in blood vessels by Sikka, Gautam, Hussmann, G. Patrick, Pandey, Deepesh, Cao, Suyi, Hori, Daijiro, Park, Jong Taek, Steppan, Jochen, Kim, Jae Hyung, Barodka, Viachaslau, Myers, Allen C., Santhanam, Lakshmi, Nyhan, Daniel, Halushka, Marc K., Koehler, Raymond C., Snyder, Solomon H., Shimoda, Larissa A., Berkowitz, Dan E.

“…Melanopsin (opsin4; Opn4), a non-image-forming opsin, has been linked to a number of behavioral responses to light, including circadian photo-entrainment,…”
Get full text

Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4 by DRAGER, Luciano F, QIAOLING YAO, SCHWARTZ, Alan R, HALBERG, Nils, SCHERER, Philipp E, SEMENZA, Gregg L, POWELL, David R, POLOTSKY, Vsevolod Y, HERNANDEZ, Karen L, SHIN, Mi-Kyung, BEVANS-FONTI, Shannon, GAY, Jason, SUSSAN, Thomas E, JUN, Jonathan C, MYERS, Allen C, OLIVECRONA, Gunilla

“…Obstructive sleep apnea is a risk factor for dyslipidemia and atherosclerosis, which have been attributed to chronic intermittent hypoxia (CIH). Intermittent…”
Get full text

IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin by Oh, Min-Hee, Oh, Sun Young, Yu, Jinho, Myers, Allen C, Leonard, Warren J, Liu, Yong Jun, Zhu, Zhou, Zheng, Tao

“…Skin fibrotic remodeling is a major feature in human atopic dermatitis (AD). Inflammation and tissue fibrosis are common consequences of Th2 responses…”
Get full text

Digoxin inhibits development of hypoxic pulmonary hypertension in mice by Abud, Edsel M, Maylor, Julie, Undem, Clark, Punjabi, Arjun, Zaiman, Ari L, Myers, Allen C, Sylvester, J. T, Semenza, Gregg L, Shimoda, Larissa A

“…Chronic hypoxia is an inciting factor for the development of pulmonary arterial hypertension. The mechanisms involved in the development of hypoxic pulmonary…”
Get full text

Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus by Liu, Zhenyu, Hu, Youtian, Yu, Xiaoyun, Xi, Jiefeng, Fan, Xiaoming, Tse, Chung-Ming, Myers, Allen C, Pasricha, Pankaj J, Li, Xingde, Yu, Shaoyong

“…Transient receptor potential A1 (TRPA1) is a newly defined cationic ion channel, which selectively expresses in primary sensory afferent nerve, and is…”
Get more information

Selective Expression of a Sodium Pump Isozyme by Cough Receptors and Evidence for Its Essential Role in Regulating Cough by Mazzone, Stuart B, Reynolds, Sandra M, Mori, Nanako, Kollarik, Marian, Farmer, David G, Myers, Allen C, Canning, Brendan J

“…We have identified a distinct subtype of airway vagal afferent nerve that plays an essential role in regulating the cough reflex. These afferents are…”
Get full text

Hypoxia-induced migration in pulmonary arterial smooth muscle cells requires calcium-dependent upregulation of aquaporin 1 by Leggett, Kyle, Maylor, Julie, Undem, Clark, Lai, Ning, Lu, Wenju, Schweitzer, Kelly, King, Landon S, Myers, Allen C, Sylvester, J T, Sidhaye, Venkataramana, Shimoda, Larissa A

“…Pulmonary arterial smooth muscle cell (PASMC) migration is a key component of the vascular remodeling that occurs during the development of hypoxic pulmonary…”
Get more information

Neurotransmitters in parasympathetic ganglionic neurons and nerves in mouse lower airway smooth muscle by Balentova, Sona, Conwell, Simone, Myers, Allen C

“…Highlights • Mice are routinely used to study airway diseases such as asthma. • Allergen-induced contraction of airway smooth muscle has a well-defined…”
Get full text

Mast cell-cholinergic nerve interaction in mouse airways by Weigand, Letitia A., Myers, Allen C., Meeker, Sonya, Undem, Bradley J.

“…We addressed the mechanism by which antigen contracts trachea isolated from actively sensitized mice. Trachea were isolated from mice (C57BL/6J) that had been…”
Get full text

Epicutaneous exposure to staphylococcal superantigen enterotoxin B enhances allergic lung inflammation via an IL-17A dependent mechanism by Yu, Jinho, Oh, Min Hee, Park, Ju-Un, Myers, Allen C, Dong, Chen, Zhu, Zhou, Zheng, Tao

“…Atopic dermatitis (AD) is the initial step of the atopic march: the progression from AD to allergic rhinitis and asthma. There is a close association between…”
Get full text

Interleukin-17F Induces Pulmonary Neutrophilia and Amplifies Antigen-induced Allergic Response by Oda, Naruhito, Canelos, Paola B, Essayan, David M, Plunkett, Beverly A, Myers, Allen C, Huang, Shau-Ku

“…Interleukin (IL)-17F is a recently described human cytokine belonging to the IL-17 gene family, but its in vivo function remains to be determined. To this end,…”
Get full text

Localization of nerve growth factor and its receptors in the human nasal mucosa by Wu, XinQun, Myers, Allen C., Goldstone, Andrew C., Togias, Alkis, Sanico, Alvin M.

“…Nerve growth factor (NGF) is a pluripotent mediator, the levels of which are elevated in nasal lavage fluids of individuals with allergic rhinitis at baseline…”
Get full text

Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guinea pig airways by Myers, Allen C, Kajekar, Radhika, Undem, Bradley J

“…In the vagal-sensory system, neuropeptides such as substance P and calcitonin gene-related peptide (CGRP) are synthesized nearly exclusively in small-diameter…”
Get more information

Constitutive and Inducible Expression of B7 Family of Ligands by Human Airway Epithelial Cells by Kim, Jean, Myers, Allen C, Chen, Lieping, Pardoll, Drew M, Truong-Tran, Quynh-Ai, Lane, Andrew P, McDyer, John F, Fortuno, Lowella, Schleimer, Robert P

“…Activated T cells have been implicated in chronic rhinosinusitis (CRS) and asthma and physically interact with epithelial cells in the airways. We now report…”
Get full text

Neurotransmitters in airway parasympathetic neurons altered by neurotrophin-3 and repeated allergen challenge by Pan, Jenny, Rhode, Holly K, Undem, Bradley J, Myers, Allen C

“…Changes in airway nerves associated with chronic inflammation may underlie the pathogenesis and symptoms of lower airway diseases, such as asthma. The…”
Get full text

Chronic intermittent hypoxia induces lung growth in adult mice by Reinke, Christian, Bevans-Fonti, Shannon, Grigoryev, Dmitry N, Drager, Luciano F, Myers, Allen C, Wise, Robert A, Schwartz, Alan R, Mitzner, Wayne, Polotsky, Vsevolod Y

“…Obstructive sleep apnea (OSA) increases cardiovascular morbidity and mortality, which have been attributed to intermittent hypoxia (IH). The effects of IH on…”
Get more information

Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs by Guo, Jin P, Brummet, Mary E, Myers, Allen C, Na, Ho Jeong, Rowland, Elizabeth, Schnaar, Ronald L, Zheng, Tao, Zhu, Zhou, Bochner, Bruce S

“…Sialic acid-binding immunoglobulin-like lectin (Siglec)-F, an inhibitory receptor on mouse eosinophils, preferentially recognizes the glycan ligand 6'-sulfated…”
Get full text

Mast cell-mediated long-lasting increases in excitability of vagal C fibers in guinea pig esophagus by Yu, Shaoyong, Kollarik, Marian, Ouyang, Ann, Myers, Allen C, Undem, Bradley J

“…Several esophageal pathologies are associated with an increased number of mast cells in the esophageal wall. We addressed the hypothesis that activation of…”
Get more information

Restoration of cough reflex in lung transplant recipients by Duarte, Alexander G, Terminella, Luigi, Smith, Jason T, Myers, Allen C, Campbell, Gerald, Lick, Scott

“…Lung transplantation involves vagal nerve interruption resulting in sensory airway denervation and impairment of the cough reflex. Following lung…”
Get more information