Search Results - "Mychaliska, George"

Ethical challenges in first-in-human trials of the artificial placenta and artificial womb: not all technologies are created equally, ethically by Kukora, Stephanie K., Mychaliska, George B., Weiss, Elliott Mark

“…Artificial placenta and artificial womb technologies to support extremely premature neonates are advancing toward clinical testing in humans. Currently, no…”
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The artificial placenta: Is clinical translation next? by Mychaliska, George B.

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Milestones for clinical translation of the artificial placenta by Spencer, Brianna L., Mychaliska, George B.

“…Despite significant advances in the treatment of prematurity, premature birth results in significant mortality and morbidity. In particular, extremely low…”
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Updates in Neonatal Extracorporeal Membrane Oxygenation and the Artificial Placenta by Spencer, Brianna L., Mychaliska, George B.

“…Extracorporeal life support, initially performed in neonates, is now commonly used for both pediatric and adult patients requiring pulmonary and/or cardiac…”
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De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders by Qi, Hongjian, Yu, Lan, Zhou, Xueya, Wynn, Julia, Zhao, Haoquan, Guo, Yicheng, Zhu, Na, Kitaygorodsky, Alexander, Hernan, Rebecca, Aspelund, Gudrun, Lim, Foong-Yen, Crombleholme, Timothy, Cusick, Robert, Azarow, Kenneth, Danko, Melissa E, Chung, Dai, Warner, Brad W, Mychaliska, George B, Potoka, Douglas, Wagner, Amy J, ElFiky, Mahmoud, Wilson, Jay M, Nickerson, Debbie, Bamshad, Michael, High, Frances A, Longoni, Mauro, Donahoe, Patricia K, Chung, Wendy K, Shen, Yufeng

“…Congenital diaphragmatic hernia (CDH) is a severe birth defect that is often accompanied by other congenital anomalies. Previous exome sequencing studies for…”
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The new frontier in ECLS: Artificial placenta and artificial womb for premature infants by Shah, Nikhil R., Mychaliska, George B.

“…Outcomes for extremely low gestational age newborns (ELGANs), defined as <28 weeks estimated gestational age (EGA), remain disproportionately poor. A radical…”
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Extracorporeal life support in neonates and children: Innovations, controversies, and promise by Gray, Brian W., Mychaliska, George B.

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Extracorporeal life support without systemic anticoagulation: a nitric oxide-based non-thrombogenic circuit for the artificial placenta in an ovine model by Fallon, Brian P., Lautner-Csorba, Orsolya, Major, Terry C., Lautner, Gergely, Harvey, Stephen L., Langley, Mark W., Johnson, Matthew D., Saveski, Claudia, Matusko, Niki, Rabah, Raja, Rojas-Pena, Alvaro, Meyerhoff, Mark E., Bartlett, Robert H., Mychaliska, George B.

“…Background Clinical translation of the extracorporeal artificial placenta (AP) is impeded by the high risk for intracranial hemorrhage in extremely premature…”
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Prenatally diagnosed severe CDH: mortality and morbidity remain high by Coughlin, Megan A, Werner, Nicole L, Gajarski, Robert, Gadepalli, Samir, Hirschl, Ronald, Barks, John, Treadwell, Marjorie C, Ladino-Torres, Maria, Kreutzman, Jeannie, Mychaliska, George B

“…Abstract Purpose This study sought to evaluate prenatal markers’ ability to predict severe congenital diaphragmatic hernia(CDH) and assess this subgroup’s…”
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Thoracoscopic Patch Repair of Congenital Diaphragmatic Hernia: Can Smaller Incisions Treat Larger Defects? by Shah, Nikhil R., Criss, Cory N., Burgi, Keerthi, Matusko, Niki, Geiger, James D., Perrone, Erin E., Mychaliska, George B., Ralls, Matthew W.

“…Thoracoscopic CDH repair is increasingly performed for Type A and small Type B defects that are amenable to primary repair. However, the thoracoscopic approach…”
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Surgical approaches to congenital diaphragmatic hernia by King, Sarah, Carr, Benjamin D.E., Mychaliska, George B., Church, Joseph T.

“…Surgical repair of the diaphragm is essential for survival in congenital diaphragmatic hernia (CDH). There are many considerations surrounding the operation –…”
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Patterns and Outcomes of Epoprostenol Use in Infants with Congenital Diaphragmatic Hernia Requiring Extracorporeal Life Support by Shah, Nikhil R., Burgi, Keerthi, Lotakis, Dimitra M., Olive, Mary K., McCormick, Amanda D., Perrone, Erin E., Church, Joseph T., Mychaliska, George B.

“…To describe our experience utilizing epoprostenol for pulmonary hypertension (PH) in infants with congenital diaphragmatic hernia (CDH) requiring…”
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Discordant prenatal ultrasound and fetal MRI in CDH: wherein lies the truth? by Kim, Aimee G., Norwitz, Gabriella, Karmakar, Monita, Ladino-Torres, Maria, Berman, Deborah R., Kreutzman, Jeannie, Treadwell, Marjorie C., Mychaliska, George B., Perrone, Erin E.

“…Prenatal risk assessment of congenital diaphragmatic hernia (CDH) relies on prenatal ultrasound (U/S) and fetal magnetic resonance imaging (MRI). When the…”
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Thoracoscopic vs Open Lobectomy in Infants and Young Children with Congenital Lung Malformations by Kunisaki, Shaun M., MD, MSc, FACS, Powelson, Ian A., BA, Haydar, Bishr, MD, Bowshier, Brian C., MD, Jarboe, Marcus D., MD, FACS, Mychaliska, George B., MD, FACS, Geiger, James D., MD, FACS, Hirschl, Ronald B., MD, FACS

“…Background Although thoracoscopic lobectomy is a widely accepted surgical procedure in adult thoracic surgery, its role in small children remains…”
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Prenatal Measurements of Congenital Lung Malformations: Can They Predict Postnatal Size? by Dougherty, Danielle, Diaconescu, Andrada, Shah, Nikhil R., VanHulle, Rachel, Ladino-Torres, Maria, Treadwell, Marjorie C., Mychaliska, George B., Perrone, Erin E.

“…Prenatally diagnosed congenital lung malformations (CLMs) are monitored via ultrasound and measured by congenital pulmonary airway malformation volume ratios…”
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Is there a best approach for extracorporeal life support cannulation: a review of the extracorporeal life support organization by Johnson, Kevin, Jarboe, Marcus D., Mychaliska, George B., Barbaro, Ryan P., Rycus, Peter, Hirschl, Ronald B., Gadepalli, Samir K.

“…Neurologic complications are common, and amongst the most devastating complications in pediatric patients undergoing extracorporeal life support (ECLS)…”
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Care Levels for Fetal Therapy Centers by Baschat, Ahmet A, Blackwell, Sean B, Chatterjee, Debnath, Cummings, James J, Emery, Stephen P, Hirose, Shinjiro, Hollier, Lisa M, Johnson, Anthony, Kilpatrick, Sarah J, Luks, Francois I, Menard, M Kathryn, McCullough, Lawrence B, Moldenhauer, Julie S, Moon-Grady, Anita J, Mychaliska, George B, Narvey, Michael, Norton, Mary E, Rollins, Mark D, Skarsgard, Eric D, Tsao, KuoJen, Warner, Barbara B, Wilpers, Abigail, Ryan, Greg

“…Fetal therapies undertaken to improve fetal outcome or to optimize transition to neonate life often entail some level of maternal, fetal, or neonatal risk. A…”
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Image-based prenatal predictors correlate with postnatal survival, extracorporeal life support use, and defect size in left congenital diaphragmatic hernia by Perrone, Erin E., Karmakar, Monita, Lally, Pamela A., Chung, Sukyung, Kipfmueller, Florian, Morini, Francesco, Phillips, Ryan, Van Meurs, Krisa P., Harting, Matthew T., Mychaliska, George B., Lally, Kevin P.

“…Objective To evaluate the association between prenatal imaging predictors of patients with left-sided congenital diaphragmatic hernia (LCDH) and postnatal…”
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Acute kidney injury in congenital diaphragmatic hernia requiring extracorporeal life support: an insidious problem by Gadepalli, Samir K, Selewski, David T, Drongowski, Robert A, Mychaliska, George B

“…Abstract Purpose Patients with congenital diaphragmatic hernia (CDH) requiring extracorporeal life support (ECLS) are at increased risk for acute kidney injury…”
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Avalon catheters in pediatric patients requiring ECMO: Placement and migration problems by Jarboe, Marcus D., Gadepalli, Samir K., Church, Joseph T., Arnold, Meghan A., Hirschl, Ronald B., Mychaliska, George B.

“…The Avalon dual-lumen venovenous catheter has several advantages, but placement techniques and management have not been adequately addressed in the pediatric…”
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